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Oncology Nurse Certification Practice Exam – Real Questions & Correct Answers PDF | OCN Test Prep & Study Guide

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Prepare for the Oncology Nurse Certification (OCN®) Exam with this PDF practice test. Includes real exam-style questions with correct answers, covering cancer care, treatments, pharmacology, and patient education. Perfect for nurses and students who want guaranteed success.

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Oncology Nursing Certification Practice
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Oncology Nursing Certification Practice










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Institution
Oncology Nursing Certification Practice
Course
Oncology Nursing Certification Practice

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Uploaded on
September 27, 2025
Number of pages
20
Written in
2025/2026
Type
Exam (elaborations)
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Questions & answers

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  • ocn practice exam

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Oncology Nursing Certification Practice Exam
With Real Questions And Correct
Answer/Guaranteed Pass/Instant Download
Pdf
1. Which of the following is the most common type of breast cancer?
A. Ductal carcinoma in situ
B. Lobular carcinoma in situ
C. Invasive ductal carcinoma
D. Inflammatory breast cancer
Answer: C
Rationale: Invasive ductal carcinoma accounts for the majority of breast cancer cases and originates in
the milk ducts.

2. A patient receiving chemotherapy reports severe nausea and vomiting. Which intervention is most
appropriate first-line management?
A. Encourage oral hydration only
B. Administer prescribed antiemetic prior to chemotherapy
C. Suggest herbal remedies
D. Restrict food intake completely
Answer: B
Rationale: Prophylactic antiemetics administered before chemotherapy are most effective in preventing
nausea and vomiting.

3. Which lab value indicates a patient is at highest risk for infection during chemotherapy?
A. Hemoglobin 12 g/dL
B. Platelets 150,000/mm³
C. Absolute neutrophil count (ANC) 400/mm³
D. Sodium 140 mmol/L
Answer: C
Rationale: Neutropenia, defined as ANC <500/mm³, significantly increases infection risk.

4. A patient with cancer is experiencing fatigue. Which nursing intervention is most effective?
A. Encourage complete bed rest
B. Encourage short periods of light activity
C. Restrict fluids
D. Limit social interactions
Answer: B

,Rationale: Light activity helps maintain strength and reduce fatigue without causing excessive energy
depletion.

5. Which is a common side effect of radiation therapy to the head and neck region?
A. Alopecia on the lower extremities
B. Xerostomia (dry mouth)
C. Peripheral neuropathy
D. Constipation
Answer: B
Rationale: Radiation to the head and neck often damages salivary glands, causing dry mouth.

6. Tumor lysis syndrome is most likely to occur in patients with:
A. Slow-growing solid tumors
B. High tumor burden hematologic malignancies
C. Early-stage skin cancer
D. Benign tumors
Answer: B
Rationale: Rapid cell lysis in hematologic cancers releases intracellular contents, leading to metabolic
disturbances.

7. A patient is scheduled for a bone marrow biopsy. Which statement indicates understanding of post-
procedure care?
A. “I can resume heavy lifting immediately.”
B. “I should avoid the biopsy site for a week.”
C. “I may have mild soreness and should keep the area clean and dry.”
D. “I will need daily dressing changes for a month.”
Answer: C
Rationale: Mild soreness is common, and proper hygiene prevents infection; heavy activity should be
avoided briefly.

8. Which is the priority nursing assessment for a patient receiving IV chemotherapy?
A. Bowel sounds
B. IV site for infiltration or extravasation
C. Lung sounds
D. Pupillary response
Answer: B
Rationale: Chemotherapy drugs are vesicants; early detection of infiltration prevents tissue damage.

9. What is the primary purpose of staging in cancer?
A. Determine patient’s diet
B. Assess extent of disease and guide treatment
C. Evaluate psychological needs
D. Predict nursing workload

, Answer: B
Rationale: Staging identifies tumor size, nodal involvement, and metastasis to guide therapy and
prognosis.

10. Which patient teaching is essential for a woman receiving tamoxifen?
A. Avoid all fruits
B. Report any signs of blood clots immediately
C. Limit sleep to 4 hours/night
D. Skip mammograms during therapy
Answer: B
Rationale: Tamoxifen increases the risk of thromboembolic events; early detection of symptoms is
critical.



11. Which sign is most indicative of superior vena cava (SVC) syndrome in a cancer patient?
A. Lower extremity edema
B. Abdominal distension
C. Facial swelling and venous distention in the neck
D. Leg pain
Answer: C
Rationale: SVC syndrome results from obstruction of venous return, leading to facial edema and
distended neck veins.

12. A patient with cancer reports numbness and tingling in hands and feet. Which chemotherapy side
effect is likely?
A. Alopecia
B. Nausea
C. Peripheral neuropathy
D. Constipation
Answer: C
Rationale: Certain chemotherapeutic agents, such as platinum compounds and taxanes, can cause
peripheral neuropathy.

13. Which nursing action is most appropriate for a patient with thrombocytopenia?
A. Encourage strenuous exercise
B. Use soft toothbrushes and monitor for bleeding
C. Administer aspirin
D. Limit fluid intake
Answer: B
Rationale: Thrombocytopenic patients are at increased risk of bleeding; gentle care and monitoring are
essential.
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