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HESI RN 2025/2026 – Complete Practice Questions & Answers | Medical-Surgical Nursing | Pharmacology | Patient Care

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This document offers a comprehensive HESI RN exam review for the 2025/2026 academic year, featuring over 50 clinically relevant, multiple-choice questions with accurate and detailed answers. It is specifically designed for nursing students preparing for the HESI RN Exit Exam or subject-specific HESI practice in areas such as medical-surgical nursing, pharmacology, pathophysiology, and patient-centered care. Key topics covered include: Pharmacological management of conditions such as diabetes, cardiovascular disorders, and infections Assessment and nursing interventions for post-op care, respiratory conditions, and neurological symptoms NCLEX-style clinical judgment scenarios for prioritizing care, identifying adverse effects, and patient teaching Terminology and medication interactions critical for safe practice Rationales provided for each answer to strengthen concept retention and boost test-taking confidence This document is highly relevant for: Nursing students in ADN, BSN, and accelerated programs NCLEX-RN candidates seeking focused HESI-style practice Instructors or tutors creating mock exams and review sessions Remediation students looking to identify knowledge gaps before final testing Formatted for clarity and aligned with current NCLEX-RN standards, this guide supports mastery of core nursing competencies and promotes success in both HESI and licensure testing environments. Keywords: HESI RN exam, nursing pharmacology, NCLEX practice, patient safety, clinical judgment, medical-surgical nursing, diabetes management, respiratory care, nursing interventions, pharmacological therapy, adverse effects, prioritization, nursing exit exam, US nursing school

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HESI RN Med-Surge Practice Exam
2025/2026 Exam Questions with 100%
Correct Answers | Latest Update



An adult client who is hospitalized after surgery reports sudden onset of

chest pain and dyspnea. the client appears anxious, restless, and mildly

cyanotic. the nurse should further assess the client for which condition?




Pulmonary embolism.

Heart failure.

Tuberculosis.


Bronchitis. - 🧠ANSWER ✔✔Pulmonary embolism

,which information should the nurse obtain when performing an initial

assessment of a client who presents to the emergency department with a

painful ankle injury? (select all that apply)




Quality of the pain.

Signs of inflammation.

Ankle range of motion.

Muscle strength testing.


Visible deformities of the joint - 🧠ANSWER ✔✔Quality of the pain


Signs of inflammation

Ankle range of motion

Visible deformities of the joint

Which description of pain is consistent with a diagnosis of rheumatoid

arthritis?




Joint pain is worse in the morning and involves symmetric joints.

,Joint pain is better in the morning and worsens throughout the day.




Joint pain is consistent throughout the day and is relieved by pain

medication.




Joint pain is worse during the day and involves unilateral joints. -

🧠ANSWER ✔✔Joint pain is worse in the morning and involves symmetric

joints

Which physical assessment finding should the nurse anticipate in a client

with long-term gastroesophagealreflux disease (GERD)?




Hoarseness.

Dry mouth.

Mouth ulcers.


Weight loss. - 🧠ANSWER ✔✔Hoarseness


A client presents with chronic venous insufficiency. Which assessment

finding should the nurse anticipate?


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, Bilateral lower leg stasis dermatitis.

Clubbing of fingers and toes.

Intermittent claudication. Incorrect


Peripheral cyanosis. - 🧠ANSWER ✔✔Bilateral lower leg stasis dermatitis


A client has been hospitalized with a femur fracture and is being treated

with traction. which action by the nurse is the priority when caring for this

client?




Assess neurovascular status.

Change the client's position.

Inspect the traction equipment.


Review pain medication orders. - 🧠ANSWER ✔✔Assess neurovascular

status

Which statement made by a client with chronic pancreatitis indicates that

further education is needed?

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