solution–Expert Verified | Latest Questions 2025
A disease where abnormal cells divide uncontrollably and destroy body tissue
2nd leading cause of death in the US - What is cancer?
~2 million - How many new cases of cancer are there projected to be in 2024?
600,000 - How many deaths are projected to occur from cancer in 2024?
Every 1 in 2 men
Every 1 in 3 women - How many men and women will get cancer at some point?
Declining since 1991
-Reduction in smoking
-Early detection for some cancers
-Improved treatment options - What is the trend for cancer mortality and why is this the
case?
HPV-associated oral cancers
Increased 2015-2019 by 2-3% annually - While cancer is declining overall, what type of
cancers are increasing?
Accounts for >90% of oral malignancies
45,000 new cases/year
11,000 deaths/year - What is the incidence and mortality of oral SCC?
Men
Caucasians
Deaths in both non-Hispanic white and black men - What groups are at risk for oral
SCC?
Chronic tobacco/nicotine use
Alcohol abuse (increases risk 15 times)
Radiation
High risk HPV infection
Nutritional deficiencies
Immune deficiencies
Hereditary conditions
Possibly chronic trauma - What is the etiology of oral cancer?
Posterior lateral border of tongue (50% of cases)
Then, ventral surface of tongue
Floor of the mouth
Soft palate