,Chapter 01: Drug Regulation, Actions, and Responses
u u u u u u
Workman & LaCharity: Understanding Pharmacology: Essentials for Medication Safety,
u u u u u u u u
u2nd Edition
u
MULTIPLE CHOICE u
uBASIC
uCONCEPTS
1. Which health care professional has the major responsibility for dispensing
u u u u u u u u u
uprescribed drugs under the direction of a pharmacist?
u u u u u u u
a. Physician
b Nurse practitioner u
.
c. Licensed nurse u
d Pharmacy technician mm
.
ANS: D
The physician and nurse practitioner have the major responsibility for prescribing
u u u u u u u u u u
udrugs, not dispensing them. The licensed nurse has the primary responsibility for
u u u u u u u u u u u
uadministering drugs, although under some circumstances a licensed nurse may dispense
u u u u u u u u u u
uprescribed drugs but this is not his or her major responsibility in drug therapy. The
u u u u u u u u u u u u u u
upharmacy technician has the major responsibility of dispensing prescribed drugs
u u u u u u u u u
uunder the direction of a licensed pharmacist.
u u u u u u
DIF: Cognitive Level: Remembering u u REF: p. 3 u
2. Which term describes the effect of a drug that improves body function?
u u u u u u u u u u u
a. Side effect u
b Intended action mm
.
c. Adverse reaction u
d Idiosyncratic response u
.
ANS: B
The purpose of drug therapy is to take a drug to prevent, reduce, or correct a
u u u u u u u u u u u u u u u
uhealth problem. This response is any drug’s intended action also known as a
u u u u u u u u u u u u
utherapeutic response. u
DIF: Cognitive Level: Remembering u u REF: p. 3 u
3. Which type of drug name is ―owned‖ by the company that manufactures it?
u u u u u u u u u u u u
a. Generic name u
b Chemical name u
, .
c. Category name u
d Trade name mm
.
ANS: D
The chemical name is a drug’s exact chemical composition. The generic name is the
u u u u u u u u u u u u u
uname assigned to the drug by the U.S. Adopted Names Council and is not owned
u u u u u u u u u u u u u u
by anyone. The category name refers to the type of drug (what it does or what it
u u u u u u u u u u u u u u u u u
is used for) and is not an actual drug name. The trade name (brand name) is the
u u u u u u u u u u u u u u u u u
name provided and owned by a specific drug’s manufacturer.
u u u u u u u u u
DIF: Cognitive Level: Remembering u u REF: p. 4 u
4.
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: B
A high alert drug is one in which harm is likely to result if given at the wrong
u u u u u u u u u u u u u u u u u
udose, to the wrong patient, or not given to the correct patient. Drugs classified as
u u u u u u u u u u u u u u
uhigh alert drugs include potassium, narcotics (opioids), insulin, cancer chemotherapy
u u u u u u u u u
udrugs, and heparin (or any drug that strongly affects blood clotting). Penicillin,
u u u u u u u u u u u
uNSAIDs, and calcium are not considered high alert drugs.
u u u u u u u u
DIF: Cognitive Level: Remembering u u REF: p. 4 u
5. What is the term for a drug that has the same action as a
u u u u u u u u u u u u u
u naturally occurring body hormone or enzyme?
u u u u u
a. Agonist
b Blocking
. agent u
c. Chemical
d Duplicator
.
ANS: A
A drug agonist is an extrinsic drug that activates the receptor sites of a cell and
u u u u u u u u u u u u u u u
umimics the actions of naturally occurring body substances (intrinsic drugs). A blocking
u u u u u u u u u u u
uagent is a drug u u u
, antagonist. A chemical would not necessarily be a drug at all. A duplicator is not a
u u u u u u u u u u u u u u u
upharmacologic term. u
DIF: Cognitive Level: Remembering u u REF: pp. 6-7 u
6. Which term describes how the body affects drug activity?
u u u u u u u u
a. Drug potency u
b Pharmacodynamics
.
c. Therapeutic effect u
d Pharmacokinetics
.
ANS: D
The term pharmacokinetics refers to drug metabolism and how the body changes a
u u u u u u u u u u u u
udrug. Pharmacodynamics refers to how a drug works to change body function.
u u u u u u u u u u u
uDrug potency refers to how strongly or to what degree a drug exerts its effects.
u u u u u u u u u u u u u u
uThe therapeutic effect is closer to pharmacodynamics, meaning how a drug works
u u u u u u u u u u u
uto change body function.
u u u
DIF: Cognitive Level: Remembering u u REF: p. 10 u
7. In the United States, which group is responsible for enforcing established
u u u u u u u u u u
ustandards for drug manufacturing?u u u
a. U.S. Pharmacopeia u
b National Institutes of Health u u u
.
c. Food and Drug Administration
mm mm mm
d Association of Pharmaceutical u u
. Manufacturers
ANS: C
The standards for drug manufacture are established by the U.S. Pharmacopeia. These
u u u u u u u u u u u
ustandards are enforced by the Food and Drug Administration. Neither the National
u u u u u u u u u u u
uInstitutes of Health nor the Association of Pharmaceutical Manufacturers has any
u u u u u u u u u u
u authority to enforce drug standards.
u u u u
DIF: Cognitive Level: Remembering u u REF: u u u p. 5 u
8. Which factor is a major disadvantage of the transdermal drug delivery route?
mm mm mm mm mm mm mm mm mm mm mm
a. Only a prescriber can administer drugs by the transdermal
u u u u u u u u
route. u
b Transdermal drugs must be sterile rather than clean. u u u u u u u
.
c. First pass drug loss by this route is the most extensive.
u u u u u u u u u u
d Drug absorption is dependent on adequate circulation.
mm mm mm mm mm mm
u u u u u u
Workman & LaCharity: Understanding Pharmacology: Essentials for Medication Safety,
u u u u u u u u
u2nd Edition
u
MULTIPLE CHOICE u
uBASIC
uCONCEPTS
1. Which health care professional has the major responsibility for dispensing
u u u u u u u u u
uprescribed drugs under the direction of a pharmacist?
u u u u u u u
a. Physician
b Nurse practitioner u
.
c. Licensed nurse u
d Pharmacy technician mm
.
ANS: D
The physician and nurse practitioner have the major responsibility for prescribing
u u u u u u u u u u
udrugs, not dispensing them. The licensed nurse has the primary responsibility for
u u u u u u u u u u u
uadministering drugs, although under some circumstances a licensed nurse may dispense
u u u u u u u u u u
uprescribed drugs but this is not his or her major responsibility in drug therapy. The
u u u u u u u u u u u u u u
upharmacy technician has the major responsibility of dispensing prescribed drugs
u u u u u u u u u
uunder the direction of a licensed pharmacist.
u u u u u u
DIF: Cognitive Level: Remembering u u REF: p. 3 u
2. Which term describes the effect of a drug that improves body function?
u u u u u u u u u u u
a. Side effect u
b Intended action mm
.
c. Adverse reaction u
d Idiosyncratic response u
.
ANS: B
The purpose of drug therapy is to take a drug to prevent, reduce, or correct a
u u u u u u u u u u u u u u u
uhealth problem. This response is any drug’s intended action also known as a
u u u u u u u u u u u u
utherapeutic response. u
DIF: Cognitive Level: Remembering u u REF: p. 3 u
3. Which type of drug name is ―owned‖ by the company that manufactures it?
u u u u u u u u u u u u
a. Generic name u
b Chemical name u
, .
c. Category name u
d Trade name mm
.
ANS: D
The chemical name is a drug’s exact chemical composition. The generic name is the
u u u u u u u u u u u u u
uname assigned to the drug by the U.S. Adopted Names Council and is not owned
u u u u u u u u u u u u u u
by anyone. The category name refers to the type of drug (what it does or what it
u u u u u u u u u u u u u u u u u
is used for) and is not an actual drug name. The trade name (brand name) is the
u u u u u u u u u u u u u u u u u
name provided and owned by a specific drug’s manufacturer.
u u u u u u u u u
DIF: Cognitive Level: Remembering u u REF: p. 4 u
4.
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: B
A high alert drug is one in which harm is likely to result if given at the wrong
u u u u u u u u u u u u u u u u u
udose, to the wrong patient, or not given to the correct patient. Drugs classified as
u u u u u u u u u u u u u u
uhigh alert drugs include potassium, narcotics (opioids), insulin, cancer chemotherapy
u u u u u u u u u
udrugs, and heparin (or any drug that strongly affects blood clotting). Penicillin,
u u u u u u u u u u u
uNSAIDs, and calcium are not considered high alert drugs.
u u u u u u u u
DIF: Cognitive Level: Remembering u u REF: p. 4 u
5. What is the term for a drug that has the same action as a
u u u u u u u u u u u u u
u naturally occurring body hormone or enzyme?
u u u u u
a. Agonist
b Blocking
. agent u
c. Chemical
d Duplicator
.
ANS: A
A drug agonist is an extrinsic drug that activates the receptor sites of a cell and
u u u u u u u u u u u u u u u
umimics the actions of naturally occurring body substances (intrinsic drugs). A blocking
u u u u u u u u u u u
uagent is a drug u u u
, antagonist. A chemical would not necessarily be a drug at all. A duplicator is not a
u u u u u u u u u u u u u u u
upharmacologic term. u
DIF: Cognitive Level: Remembering u u REF: pp. 6-7 u
6. Which term describes how the body affects drug activity?
u u u u u u u u
a. Drug potency u
b Pharmacodynamics
.
c. Therapeutic effect u
d Pharmacokinetics
.
ANS: D
The term pharmacokinetics refers to drug metabolism and how the body changes a
u u u u u u u u u u u u
udrug. Pharmacodynamics refers to how a drug works to change body function.
u u u u u u u u u u u
uDrug potency refers to how strongly or to what degree a drug exerts its effects.
u u u u u u u u u u u u u u
uThe therapeutic effect is closer to pharmacodynamics, meaning how a drug works
u u u u u u u u u u u
uto change body function.
u u u
DIF: Cognitive Level: Remembering u u REF: p. 10 u
7. In the United States, which group is responsible for enforcing established
u u u u u u u u u u
ustandards for drug manufacturing?u u u
a. U.S. Pharmacopeia u
b National Institutes of Health u u u
.
c. Food and Drug Administration
mm mm mm
d Association of Pharmaceutical u u
. Manufacturers
ANS: C
The standards for drug manufacture are established by the U.S. Pharmacopeia. These
u u u u u u u u u u u
ustandards are enforced by the Food and Drug Administration. Neither the National
u u u u u u u u u u u
uInstitutes of Health nor the Association of Pharmaceutical Manufacturers has any
u u u u u u u u u u
u authority to enforce drug standards.
u u u u
DIF: Cognitive Level: Remembering u u REF: u u u p. 5 u
8. Which factor is a major disadvantage of the transdermal drug delivery route?
mm mm mm mm mm mm mm mm mm mm mm
a. Only a prescriber can administer drugs by the transdermal
u u u u u u u u
route. u
b Transdermal drugs must be sterile rather than clean. u u u u u u u
.
c. First pass drug loss by this route is the most extensive.
u u u u u u u u u u
d Drug absorption is dependent on adequate circulation.
mm mm mm mm mm mm