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NR 507 – Week 5 Edapt: Peptic Ulcer Disease (2025–2026) | Study Guide PDF – Chamberlain

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This NR 507 – Week 5 Edapt: Peptic Ulcer Disease (2025–2026, Chamberlain University, Advanced Pathophysiology) study guide provides a comprehensive, exam-focused review of peptic ulcer disease (PUD), covering pathophysiology, risk factors, clinical features, diagnostics, and management. Key sections include: Pathophysiology – breakdown of gastric mucosal defenses, H. pylori infection, and NSAID-induced ulcers. Risk Factors – H. pylori, NSAIDs, smoking, alcohol, obesity, family history, age >65, and Zollinger-Ellison syndrome. Clinical Manifestations – duodenal vs gastric ulcer pain, nocturnal pain, anorexia, vomiting, GI bleeding, perforation, and peritonitis. Diagnosis – endoscopy, biopsy, urea breath test, IgG/IgA, and stool antigen testing. Treatment – PPIs, H2 blockers, antacids, antibiotics for H. pylori, sucralfate, bismuth, and surgical management for complications. Perfect for 2025–2026 nursing students, NP learners, and advanced pathophysiology courses, this guide supports exam prep, assignments, and clinical discussions with concise and reliable content. NR 507 2025 study guide, NR 507 peptic ulcer 2026, Chamberlain NR 507 Edapt, NR 507 week 5 study PDF, NR 507 advanced pathophysiology 2025, NR 507 PUD risk factors, NR 507 gastric ulcer review, NR 507 duodenal ulcer notes, NR 507 nursing exam prep 2026, NR 507 gastrointestinal disorders, NR 507 nursing test prep PDF, NR 507 chamberlain 2025 resources, NR 507 assignments solved, NR 507 Edapt PUD 2026, NR 507 clinical manifestations, NR 507 exam prep guide, NR 507 nursing school 2025, NR 507 practice

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Uploaded on
September 24, 2025
Number of pages
13
Written in
2025/2026
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WEEK 5 Edapt:
Peptic Ulcer Disease
Key Concepts

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NR 507: Week 5 Edapt: Peptic Ulcer Disease




PUD is commonly associated with Helicobacter pylori (H. pylori) bacterial infection. H. pylori can colonize the gastric
mucosa, leading to chronic inflammation and disruption of the mucosal barrier. This can result in increased acid
secretion, impaired mucus production, and the development of ulcers.




Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are well-known risk factors for PUD. Regular and
prolonged use of NSAIDs can interfere with the protective mechanisms of the gastrointestinal mucosa, leading to the
development of ulcers.

Excessive alcohol consumption is a recognized risk factor for PUD. Alcohol can irritate the gastric mucosa and
increase the production of gastric acid, contributing to the development of ulcers.

Advancing age is associated with an increased risk of PUD. Older individuals may experience changes in the
mucosal lining of the stomach that make them more susceptible to ulcers.

A family history of PUD suggests a potential genetic predisposition. Genetic factors may influence an individual's
susceptibility to developing ulcers.




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