Pharmacotherapeutics for Advanced Practice: A Practical Approach, 5th Edition (Arcangelo et al.) | 2025 Exam Test Bank & Study Revision Guide | Complete Verified Questions & Answers

TestBankforPharmacotherapeuticsforAdvancedPracticeA
sPracticalApproach5thEditionByVirginiaPooleArcangelo,
AndrewMPeterson,VeronicaWilbur,TepM.Kang/All
s s s s s s s s s




ChaptersCovered–LatestUpdate2024. s




Nursepractitionerprescriptiveauthorityisregulatedby:

1. TheNationalCouncilofStateBoardsofNursing

2. TheU.S.DrugEnforcement Administration v




3. TheStateBoardofNursingforeachstate

4. TheStateBoardofPharmacy - Correct Answer - 3. The State Board of Nursing for each state s v v v v v v v v v v v v




ThebenefitstothepatientofhavinganAdvancedPracticeRegisteredNurse(APRN)prescriberinclude: s s s




1. NursesknowmoreaboutPharmacologythanotherprescribersbecausetheytakeitbothintheirbasic
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nursing program and in their APRN program.
s s s s s s s




2. Nursescareforthepatientfromaholisticapproachandincludethepatient indecisionmaking s s v s




regardingtheircare.
s s s




3. APRNsarelesslikelyto prescribenarcoticsandothercontrolledsubstances. s




4. APRNsareabletoprescribeindependentlyinallstates,whereasaphysician'sassistantneeds tohavea v s




physiciansupervising their practice. - Correct Answer - 2. Nurses care for the patient from a holistic
s s s s s
v v v v v v v v v v v



approach and include the patient in decision making regarding their care.
v v v v v v v v v v v




Clinicaljudgmentinprescribingincludes:

1. Factoringinthecosttothepatientofthemedicationprescribed
s s s s




2. Alwaysprescribingthenewestmedicationavailable for thediseaseprocess s s s




3. Handingout drugsamplestopoorpatients v s s




4. Prescribingallgenericmedicationstocutcosts - Correct Answer - 1. Factoring in the cost to the s s v v v v v v v v v v vv


patient of the medication prescribed
v v v v




pg. 1
s

,Criteriaforchoosing aneffectivedrugforadisorderinclude: v




1. Askingthepatientwhatdrugthey thinkwouldworkbestforthem
s s s s s




2. Consultingnationallyrecognizedguidelinesfordiseasemanagement

3. Prescribingmedicationsthat areavailableas samples beforewritingaprescription s s s




4. FollowingU.S.DrugEnforcementAdministration guidelinesforprescribing - Correct Answer - 2. s s s v v v vv


Consulting nationally recognized guidelines for disease management
v v v v v v




Nursepractitionerpracticemay thriveunderhealth-carereformbecauseof: s




1. Thedemonstratedabilityofnursepractitionerstocontrolcostsandimprovepatientoutcomes s s




2. Thefactthatnursepractitionerswillbeabletopracticeindependently

3. The fact thatnursepractitionerswillhave fullreimbursementunderhealth-carereform
s s s s




4. Theabilityto shiftaccountabilityforMedicaidtothestatelevel - Correct Answer - 1. The
s v s s s
v v v v v



demonstrated ability of nurse practitioners to control costs and improve patient outcomes
s v v v v v v v v v v v




Apatient'snutritionalintake andlaboratoryresultsreflecthypoalbuminemia.This is v s s s




critical toprescribingbecause:
s s s s




1. Distributionofdrugstotarget tissuemaybeaffected. s s s s




2. Thesolubilityofthedrugwill notmatchthe siteof absorption. s s s




3. Therewillbeless freedrugavailableto generateaneffect. v v




4. Drugs boundtoalbuminarereadilyexcretedbythekidneys.-Correct Answer - 1. Distribution of drugs to
v s s s s v v v v v v v



target tissue may be affected.
v v v v v




Drugsthathaveasignificantfirst-pass effect:
s s s v




1. Mustbegivenbytheenteral(oral)routeonly

2. Bypassthehepaticcirculation s




3. Arerapidlymetabolizedby theliverandmayhavelittleifanydesiredaction s




pg. 2 s

,4. Areconvertedbythelivertomoreactiveandfat-solubleforms - Correct Answer - 3. Are rapidly v s v v v v v vv


metabolized by the liver and may have little if any desired action
v v v v v v v v v v v




Therouteofexcretionofavolatiledrugwilllikelybethe:
s s s s s s




1. Kidneys

2. Lungs

3. Bileandfeces s




4. Skin - Correct Answer - 2. Lungs
v v v v v v




Medroxyprogesterone(DepoProvera)isprescribedintramuscularly(IM)tocreateastoragereservoirofthe s




drug. Storage reservoirs:
s s s




1. Assurethatthedrugwillreach itsintendedtarget tissue s s s




2. Arethereasonforgivingloadingdoses s s




3. Increasethelengthoftime adrugis availableandactive s v




4. Aremostcommonincollagentissues- Correct Answer - 3. Increase the length of time a drug is s s s v v v v v v v v v v v v vv


available and active v v




TheNPchoosestogivecephalexinevery8hours basedonknowledgeofthedrug's: s s v




1. Propensitytogotothetargetreceptor s s




2. Biological half-life s




3. Pharmacodynamics

4. Safetyandsideeffects-Correct Answer - 2. Biological half-life v v v v v




Azithromycindosingrequiresthatthefirstday'sdosagebetwicethoseoftheother 4days ofthe prescription. s s s s s s s s v s s




This isconsidered a loadingdose. A loadingdose:
s s s s s s s s s




1. Rapidlyachievesdruglevels inthetherapeuticrange
s s




2. Requiresfour-to five-half-livestoattain v




3. Isinfluencedbyrenalfunction

4. Isdirectly relatedtothedrugcirculatingtothetargettissues - Correct Answer - 1. Rapidly achieves
s s s v v v v v vv


drug levels in the therapeutic range
v v v v v




pg. 3
s

, Thepointintimeonthedrugconcentrationcurvethatindicatesthefirstsignofatherapeuticeffectisthe:
s s s s s s s s s s s s




1. Minimumadverseeffectlevel s s s




2. Peak ofaction v




3. Onsetofaction s




4. Therapeuticrange-Correct Answer - 3. Onset of action s v v v v v v




Phenytoinrequiresthatatroughlevelbe drawn.Peakandtroughlevelsare done: s s s s s




1. Whenthedrughasawidetherapeuticrange
s s s s




2. Whenthe drugwillbeadministeredforashorttimeonly
v s s s s




3. Whenthereisahighcorrelationbetweenthedoseandsaturationofreceptorsites
s s s s s s s




4. Todetermineifadrug isinthetherapeuticrange - Correct Answer - 4. To determine if a drug is in the
v s s v v v v v v v v v v v vv


therapeutic range v




Alaboratoryresultindicatesthatthepeaklevelforadrug isabovetheminimum toxicconcentration. Thismeans
s s s v s s s




thatthe:
s s




1. Concentrationwillproduce therapeuticeffects s s s




2. Concentrationwillproduceanadverseresponse

3. Timebetweendosesmustbeshortened

4. Durationofactionofthedrugistoolong-Correct Answer - 2. Concentration will produce an adverse s s s v v v v v v v v



response
s




Drugsthatarereceptoragonistsmaydemonstratewhatproperty?

1. Irreversiblebindingto thedrugreceptorsite s s




2. Upregulationwithchronicuse

3. Desensitizationordownregulationwithcontinuoususe s s s s s




4. Inverserelationshipbetweendrugconcentrationanddrugaction- Correct Answer - 3. Desensitization or s s v v v v v v



downregulation with continuous use
v v v v




pg.4 s