CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS
LATEST ALREADY GRADED A+ 2025 – 2026
What laboratory abnormalities are common in chronic
alcohol use? - ANSWERS-Elevated liver enzymes (AST > ALT)
Macrocytosis (MCV >100 fL) - Due to folate deficiency
Thiamine (Vitamin B1) deficiency - Risk of Wernicke-
Korsakoff syndrome
Hypoglycemia - Due to impaired gluconeogenesis
What laboratory findings are associated with opioid use
disorder? - ANSWERS-Hypoxia - Due to respiratory
depression
Elevated creatine kinase (CK) - Due to rhabdomyolysis in
overdose cases
,Low testosterone levels - Common in chronic opioid use
DSM-5-TR Criteria for Substance Use Disorders (SUD)
What are the DSM-5-TR criteria for diagnosing a substance
use disorder? - ANSWERS-The 11 criteria are grouped into 4
categories:
Impaired control: Larger amounts/longer use, cravings,
unsuccessful attempts to cut down
Social impairment: Neglecting responsibilities,
social/occupational problems
Risky use: Continued use despite dangers
Pharmacologic criteria: Tolerance and withdrawal
What are the symptoms of alcohol withdrawal? - ANSWERS-
Tremors (6-12 hours after last drink)
Anxiety, agitation
Tachycardia, hypertension
Insomnia
Seizures (12-48 hours after last drink)
Delirium tremens (DTs) - Hallucinations, confusion,
autonomic instability (48-72 hours after last drink)
, What is delirium tremens (DTs), and when does it occur? -
ANSWERS-A severe alcohol withdrawal syndrome with
confusion, hallucinations, and autonomic hyperactivity
(tachycardia, hypertension). Occurs 48-72 hours after last
drink.
What is the first-line treatment for acute alcohol
withdrawal? - ANSWERS-Benzodiazepines (e.g., lorazepam,
diazepam, chlordiazepoxide) to prevent seizures and DTs.
What medications are FDA-approved for alcohol use
disorder? - ANSWERS-Naltrexone - Blocks opioid receptors,
reduces cravings
Acamprosate - Modulates glutamate, reduces cravings
Disulfiram - Inhibits aldehyde dehydrogenase, causing an
aversive reaction if alcohol is consumed
Which medication should be avoided in patients with liver
disease? - ANSWERS-Naltrexone (can cause hepatotoxicity)
What are common screening tools for alcohol use disorder?
- ANSWERS-AUDIT (Alcohol Use Disorders Identification
Test) - Identifies hazardous drinking