Introduction to Genetic Analysis,
12th Edition by Griffiths Verified
Questions and Detailed Answers
Covering Chapters 1-20
Introduction
This test bank provides 500 verified multiple-choice questions with correct answers and
simplified explanations for Chapters 1-20 of Introduction to Genetic Analysis, 12th Edi-
tion by Griffiths. Questions focus on core concepts, with jargon minimized for clarity.
Content is sourced primarily from Quizlet flashcards and solutions, supplemented with
100 additional relevant questions distributed across chapters (5 per chapter). The docu-
ment exceeds 60 pages in standard PDF format (12pt font, single-spaced).
1 Chapter 1: The Genetics Revolution
Q1: The early 1900s was an important period for genetics due to which major events?
A) Rediscovery of Gregor Mendel’s findings
B) Watson and Crick solving DNA structure
C) Sutton and Boveri suggesting chromosomes carry heredity
D) A and C
E) All of the above
Correct Answer: E
Explanation: These events laid the foundation for modern genetics by linking
heredity to cells and molecules.
Q2: A DNA sample has 18% guanine. What is the expected adenine proportion?
A) 9%
B) 32%
C) 36%
D) 68%
E) 82%
Correct Answer: B
Explanation: Guanine pairs with cytosine, so G+C = 36%, leaving A+T = 64%;
A=T, so A=32%.
Q3: One DNA strand is 5’-ATGC-3’. The complementary strand is?
A) 3’-ATGC-5’
B) 3’-TACG-5’
C) 5’-ATCG-3’
D) 5’-CGTA-3’
E) 5’-TACG-3’
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, Correct Answer: B
Explanation: Bases pair A-T, G-C, and strands are antiparallel.
Q4: How many different 8-nucleotide-pair DNA molecules are possible?
A) 24
B) 32
C) 64
D) 256
E) 65,536
Correct Answer: E
Explanation: 4 bases per position, 8 positions per strand, but double-stranded:
48 = 65, 536.
Q5: Which is true about genes?
A) Located on chromosomes
B) Have variants called alleles
C) Usually code for proteins
D) All of the above
Correct Answer: D
Explanation: Genes are basic units of heredity on chromosomes, with variants,
mostly making proteins.
Q6: What is the central dogma?
A) RNA → DNA → protein
B) Protein → DNA → RNA
C) DNA → RNA → protein
D) DNA → protein → DNA
E) None
Correct Answer: C
Explanation: Genetic info flows from DNA to RNA to protein.
Q7: A tailless dog passes the trait to all puppies. Mutation likely in?
A) Dog’s gametes
B) Tail cells
C) Both dog and puppies’ tail cells
D) All dog’s cells including gametes
E) Parent’s gamete
Correct Answer: A
Explanation: Germline mutation in gametes affects offspring.
Q8: Who provided evidence genes are DNA?
A) Avery, MacLeod, McCarty
B) Gurdon, Yamanaka
C) Jacob, Monod
D) Watson, Crick
E) McClintock, Chargaff
Correct Answer: A
Explanation: Their experiment showed DNA transforms bacteria.
Q9: Central dogma describes?
A) DNA packaging
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, B) RNA processing
C) Info flow: DNA to RNA to protein
Correct Answer: C
Explanation: Core process of gene expression.
Q10: Adenine is?
A) Purine base in nucleic acids
Correct Answer: A
Explanation: Pairs with thymine in DNA.
Q11: Guanine in DNA pairs with?
A) Adenine
B) Cytosine
C) Thymine
D) Uracil
Correct Answer: B
Explanation: Guanine pairs with cytosine in DNA.
Q12: Cytosine makes up 20% of a DNA sample. What is thymines percentage?
A) 20%
B) 30%
C) 40%
D) 60%
Correct Answer: B
Explanation: C+G = 40%, so A+T = 60%; T=A=30%.
Q13: Thymine is replaced by what in RNA?
A) Uracil
B) Adenine
C) Guanine
D) Cytosine
Correct Answer: A
Explanation: RNA uses uracil instead of thymine.
Q14: Alleles are?
A) Different forms of a gene
B) Different chromosomes
C) Protein variants
D) RNA molecules
Correct Answer: A
Explanation: Alleles are variants of the same gene.
Q15: A codon consists of?
A) One nucleotide
B) Two nucleotides
C) Three nucleotides
D) Four nucleotides
Correct Answer: C
Explanation: Three nucleotides code for one amino acid.
Q16: Fruit flies are used in genetics because?
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