INTRODUCTION TO GENETIC
ANALYSIS, 12TH EDITION BY
GRIFFITHS VERIFIED QUESTIONS
AND DETAILED ANSWERS
COVERING CHAPTERS 1-20
Comprehensive Questions and Answers Covering All 20 Chapters
,Contents
1 Chapter 1: The Genetics Revolution in the Life Sciences . . . . . . . . . . . . 3
2 Chapter 2: Single-Gene Inheritance . . . . . . . . . . . . . . . . . . . . . . . . 5
3 Chapter 3: Independent Assortment of Genes . . . . . . . . . . . . . . . . . . 6
4 Chapter 4: Mapping Eukaryote Chromosomes by Recombination . . . . . . 7
5 Chapter 5: The Genetics of Bacteria and Their Viruses . . . . . . . . . . . . . 8
6 Chapter 6: Gene Interaction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
7 Chapter 7: DNA: Structure and Replication . . . . . . . . . . . . . . . . . . . 10
8 Chapter 8: RNA: Transcription, Processing, and Decay . . . . . . . . . . . . . 10
9 Chapter 9: Proteins and Their Synthesis . . . . . . . . . . . . . . . . . . . . . 11
10 Chapter 10: Gene Isolation and Manipulation . . . . . . . . . . . . . . . . . . 12
11 Chapter 11: Regulation of Gene Expression in Bacteria . . . . . . . . . . . . . 14
12 Chapter 12: Regulation of Transcription in Eukaryotes . . . . . . . . . . . . . 15
13 Chapter 13: Regulation of Gene Expression by RNA . . . . . . . . . . . . . . 15
14 Chapter 14: Genome and Genomics . . . . . . . . . . . . . . . . . . . . . . . . 16
15 Chapter 15: The Dynamic Genome: Transposable Elements . . . . . . . . . . 17
16 Chapter 16: Mutation, Repair, and Recombination . . . . . . . . . . . . . . . 18
17 Chapter 17: Inheritance of Complex Traits . . . . . . . . . . . . . . . . . . . . 19
18 Chapter 18: Evolution of Genes, Traits, and Species . . . . . . . . . . . . . . . 19
19 Chapter 19: Analyzing Human Pedigrees and the Molecular Basis of Disease 20
20 Chapter 20: Neurogenetics and the Genetics of Behavior . . . . . . . . . . . 21
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, Test Bank: Introduction to Genetic Analysis, 12th Edition
1 Chapter 1: The Genetics Revolution in the Life Sci-
ences
1. What must cellular structures that carry genetic information be capable of to
cover all aspects of an organism’s body?
Answer: They must be capable of having many different forms.
Explanation: This allows the structures to support various body parts and func-
tions, such as forming eyes or muscles.
2. What ability must cellular information have to pass from parent to offspring?
Answer: It must be able to copy itself.
Explanation: Copying ensures offspring receive the same genetic instructions as
the parent.
3. Why must the structures carrying genetic information be able to change?
Answer: To allow evolution to create new and different organisms.
Explanation: Changes help species adapt over time, leading to diversity.
4. What must cells have to read the inherited information at specific times dur-
ing development?
Answer: Machinery to read the blueprints of the organism.
Explanation: This process follows instructions at key moments, like during growth.
5. What are genes, and who coined the term in 1909?
Answer: Genes are the basic parts of inherited information; the term was coined
by Wilhelm Johannsen.
Explanation: Genes act as instructions for building and operating the body.
6. What is a genome?
Answer: It is all the genes in an organism, including DNA inside and outside
the nucleus.
Explanation: It’s the full set of genetic instructions, like a complete recipe book.
7. What is genetics, and who started this field of study in 1865?
Answer: Genetics is the study of how genetic information varies, copies, changes,
and is read; it was started by Gregor Mendel.
Explanation: It explains inheritance, like family resemblances, through experi-
ments with plants.
8. What do proteins do in organisms?
Answer: They build the body’s structure and support active processes, like di-
gestion or movement.
Explanation: Proteins work like builders and operators in the body.
9. What is DNA, and what does it do?
Answer: DNA is a large molecule that holds all the genetic information needed
to make proteins.
Explanation: It’s a master plan that guides cells in creating essential components
for life.
10. What are nucleotide bases, and how many kinds make up DNA?
Answer: Nucleotide bases are parts that stick out from DNA’s backbone; there
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