ASCP MLS UPDATED ACTUAL Exam Questions and
CORRECT Answers
1. CA-125 ovarian cancer tumor marker
2. PSA, PAP prostate tumor marker
3. CA-15-3 Breast Cancer Tumor Marker
4. CEA colon cancer tumor marker
5. hsCRP increased in? AMI, inflammation
6. lactate dehydrogenase Monitors tissue damage, widely distributed through-
out the body
7. creatine kinase Found in cardiac, brain, skeletal muscle
8. CK-MB Increased in AMI
9. CK-MM Increased in muscular disease
10. ALT increased in... Hepatitis
11. AST increased in... Hepatitis
12. Alkaline phosphatase increased in... Hepatitis and bone disorders (found in hepatobiliary
and bone)
13. GGT increased in... Recent alcohol use, liver disorders
14. Amylase increased in... Pancreatitis, not very specific
15. Lipase increased in... Pancreatitis, more specific, but rises slower
16. Apolipoproteins Proton component free from lipid
17. Friedewald Calculation is for... Calculating LDL
, ASCP MLS UPDATED ACTUAL Exam Questions and
CORRECT Answers
18. Friedewald calculation (Total chol) - (HDL chol)-(Trig/5)
19. Insulin released when? Increased blood glucose
20. Glucagon released when? Decreased blood glucose
21. Glycogenolysis breakdown of glycogen to glucose
22. Glycolysis Breakdown of glucose
23. Insulin does what in the body? Decrease glycogenolysis and glycolysis, increase glu-
cose uptake by cells
24. Glucagon does what in the body? Increase glycogenolysis, signals liver to breakdown
glucose and fat
25. Glucose produced where? Produced in liver
26. Hemoglobin is broken down into... CO, Globin, Iron, Bilirubin
(4)
27. Unconjugated bilirubin Indirect, insoluble, bound to albumin
28. conjugated bilirubin Direct, bound to water soluble molecule
29. What type of bilirubin is found in Unconjugated bilirubin
urine?
30. Urobilinogen Even more water soluble and easy to excrete than conj.
Bilirubin
31. prehepatic jaundice Increased bilirubin production due to hemolysis or
ineffective erythropoiesis
32. hepatic jaundice
, ASCP MLS UPDATED ACTUAL Exam Questions and
CORRECT Answers
Abnormal bilirubin metabolism (e.g. cell damage, he-
patitis)
33. Post-hepatic jaundice Decreased bilirubin excretion, usually caused by ob-
struction
34. Test results in PRE hepatic jaundice Increased indirect serum bilirubin, stool and urine
urobilinogen. Normal direct serum bilirubin.
35. Proteins, in order of most anodic to Prealbumin, albumin, alpha 1, alpha 2, beta, gamma
least anodic
36. Albumin decreased in... Inflammation and protein loss
37. Ceruloplasmin transports copper
38. Transferrin transports iron
39. IgG, IgM and IgA: increased in pro- In inflammation and in monoclonal spikes in myeloma
tein electrophoresis when...
40. Test results in dehydration Increased total protein, increased albumin, increased
Serum Na, Increased Osmo
41. proteinuria is associated with... Disease of the kidney, such as glomerular nephritis
42. Test results in multiple myeloma Increased total protein in serum, decr. albumin,
decr. albumin:globulin ratio, prescience of monoclon-
al paraproteins
43. Nephropathy Disease of the kidneys caused by damage to the small
blood vessels
44. Non-protein nitrogenous sub- Come from breakdown of protein and nucleic acid
stances
CORRECT Answers
1. CA-125 ovarian cancer tumor marker
2. PSA, PAP prostate tumor marker
3. CA-15-3 Breast Cancer Tumor Marker
4. CEA colon cancer tumor marker
5. hsCRP increased in? AMI, inflammation
6. lactate dehydrogenase Monitors tissue damage, widely distributed through-
out the body
7. creatine kinase Found in cardiac, brain, skeletal muscle
8. CK-MB Increased in AMI
9. CK-MM Increased in muscular disease
10. ALT increased in... Hepatitis
11. AST increased in... Hepatitis
12. Alkaline phosphatase increased in... Hepatitis and bone disorders (found in hepatobiliary
and bone)
13. GGT increased in... Recent alcohol use, liver disorders
14. Amylase increased in... Pancreatitis, not very specific
15. Lipase increased in... Pancreatitis, more specific, but rises slower
16. Apolipoproteins Proton component free from lipid
17. Friedewald Calculation is for... Calculating LDL
, ASCP MLS UPDATED ACTUAL Exam Questions and
CORRECT Answers
18. Friedewald calculation (Total chol) - (HDL chol)-(Trig/5)
19. Insulin released when? Increased blood glucose
20. Glucagon released when? Decreased blood glucose
21. Glycogenolysis breakdown of glycogen to glucose
22. Glycolysis Breakdown of glucose
23. Insulin does what in the body? Decrease glycogenolysis and glycolysis, increase glu-
cose uptake by cells
24. Glucagon does what in the body? Increase glycogenolysis, signals liver to breakdown
glucose and fat
25. Glucose produced where? Produced in liver
26. Hemoglobin is broken down into... CO, Globin, Iron, Bilirubin
(4)
27. Unconjugated bilirubin Indirect, insoluble, bound to albumin
28. conjugated bilirubin Direct, bound to water soluble molecule
29. What type of bilirubin is found in Unconjugated bilirubin
urine?
30. Urobilinogen Even more water soluble and easy to excrete than conj.
Bilirubin
31. prehepatic jaundice Increased bilirubin production due to hemolysis or
ineffective erythropoiesis
32. hepatic jaundice
, ASCP MLS UPDATED ACTUAL Exam Questions and
CORRECT Answers
Abnormal bilirubin metabolism (e.g. cell damage, he-
patitis)
33. Post-hepatic jaundice Decreased bilirubin excretion, usually caused by ob-
struction
34. Test results in PRE hepatic jaundice Increased indirect serum bilirubin, stool and urine
urobilinogen. Normal direct serum bilirubin.
35. Proteins, in order of most anodic to Prealbumin, albumin, alpha 1, alpha 2, beta, gamma
least anodic
36. Albumin decreased in... Inflammation and protein loss
37. Ceruloplasmin transports copper
38. Transferrin transports iron
39. IgG, IgM and IgA: increased in pro- In inflammation and in monoclonal spikes in myeloma
tein electrophoresis when...
40. Test results in dehydration Increased total protein, increased albumin, increased
Serum Na, Increased Osmo
41. proteinuria is associated with... Disease of the kidney, such as glomerular nephritis
42. Test results in multiple myeloma Increased total protein in serum, decr. albumin,
decr. albumin:globulin ratio, prescience of monoclon-
al paraproteins
43. Nephropathy Disease of the kidneys caused by damage to the small
blood vessels
44. Non-protein nitrogenous sub- Come from breakdown of protein and nucleic acid
stances
