Paroxetine dosing:
20-50mg daily
SSRI that is NOT recommended during pregnancy:
Possible heart defects.
paroxetine
Caution with SSRI's in young adults:
Suicidal ideation at start of treatment
SSRI that works well in the treatment of anxiety with OCD
features:
- Important to note that this medication is very sedating.
fluvoxamine (Luvox)
Dosing for sertraline (zoloft):
50-200mg
Common side effects of SSRI's
GI distress for the first 2 weeks (generally resolves), sexual
dysfunction, sweating, bruising
SSRI's may activate ____
Undiagnosed Bipolar
In patient's experiencing decreased libido on an SSRI you may
add low dose _____ to combat this effect.
,Wellbutrin
Citalopram common side effect:
Sedating
Antidepressant therapeutic effect around ___ weeks. Side effects
seen much sooner.
4-6 weeks
Dose titration/increase if no effective on antidepressant at ___
weeks.
4
Venlafaxine (SNRI) increases:
Half-life: ____
Serotonin, Norepinephrine, Dopamine
9-13 hours
Common side effects with SNRI:
Sedation, increased BP, insomnia, sweating, sexual dysfunction
Venlafaxine (SNRI) should not be given to patients with:
Angle closure glaucoma
Duloxetine increases:
Half-life:
Serotonin
12 hours
duloxetine standard dosing
60mg daily
, _____ is a serotonin stabilizer
Buspirone (Buspar)
_______ has a very SHORT life and therefore requires multiple
doses per day.
Buspirone (Buspar)
Major side effects of buspirone:
Dizziness, headache, sedation
(Multiple doses required and therefore heavier doses should be
given at PM)
______ drug class inhibits GABA.
Benzodiazepimes
GABA (gamma-aminobutyric acid)
A major inhibitory neurotransmitter.
Lorazepam (Ativan) wean:
10-25%
Diazepam (Valium) half life:
20-50 hours
Benzodiazepam side effects
Drowsiness, sedation, dizziness, slurred speech, weakness,
forgetfulness, confusion, HIGHLY addictive and contribute to
OD's and hospitalizations