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Pathophysiology, Canadian Edition,
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2nd Edition by Kelly Power-Kean,
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Chapter 1 - 42 b b b b
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PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY
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Unit 1: The Cell
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1. Cellular Biology b
2. Genes and Genetic Diseases
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3. Epigeneticsand Disease b b
4. Altered Cellular and Tissue Biology
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5. Fluids and Electrolytes, Acids and Bases
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Unit 2: Mechanisms of Self-Defense
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6. Innate Immunity: Inflammation and Wound Healing
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7. Adaptive Immunity b
8. Infection and Defects in Mechanisms of Defense
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9. Stress and Disease
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Unit 3: Cellular Proliferation: Cancer
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10. Biologyof Cancer b b
11. Cancer Epidemiology b
12. Cancer in Children and Adolescents
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PART TWO: BODY SYSTEMS AND DISEASES
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Unit 4: The Neurologic System
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13. Structureand Function of the Neurologic System b b b b b b
14. Pain, Temperature, Sleep, and Sensory Function
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15. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function b b b b b b b b
16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction
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17. Alterationsof Neurologic Function in Children b b b b b
Unit 5: The EndocrineSystem
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18. Mechanisms of Hormonal Regulation b b b
19. Alterations of Hormonal Regulation b b b
Unit 6: The Hematologic System
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20. Structureand Function of the Hematologic System b b b b b b
21. Alterations in Hematologic Function b b b
22. Alterations of Hematologic Function in Children b b b b b
Unit 7: The Cardiovascular and Lymphatic Systems
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23. Structureand Function of theCardiovascular and Lymphatic Systems
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24. Alterations of Cardiovascular Function b b b
25. Alterations of Cardiovascular Function in Children b b b b b
Unit 8: The Pulmonary System
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26. Structure and Function of the PulmonarySystem b b b b b b
27. Alterations of Pulmonary Function b b b
28. Alterations of PulmonaryFunction in Children b b b b b
Unit 9: The Renal and Urologic Systems
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29. Structure and Function of the Renal and Urologic Systems b b b b b b b b
30. Alterations of Renal and UrinaryTract Function b b b b b b
31. Alterations of Renal and UrinaryTract Function in Children b b b b b b b b
,Unit 10: The Reproductive Systems
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32. Structureand Function of the Reproductive Systems
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33. Alterations of the Female Reproductive System
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34. Alterations of the Male Reproductive System
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Unit 11: The Digestive System
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35. Structure and Function of the Digestive System
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36. Alterations of Digestive Function
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37. Alterations in Digestive Function in Children
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Unit12:The Musculoskeletal and Integumentary Systems
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38. Structure and Function of the Musculoskeletal System
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39. Alterations of Musculoskeletal Function
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40. Alterations of Musculoskeletal Function in Children
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41. Structure, Function, and Disorders of the Integument
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42. Alterations of the Integument in Children
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, Chapter01:CellularBiology
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MULTIPLECHOICE b
1. Astudent is observinga cell underthemicroscope. It is observed to havesupercoiled DNA with
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histones. Which of the following would also be observed by the student?
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a. A single circular chromosome
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b. A nucleus b
c. Free-floatingnuclearmaterial b b
d. Noorganelles b
ANS: B b
Thecell described is a eukaryoticcell, so it has histones and asupercoiled DNA within its nucleus;
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thus, the nucleus should be observed. A single circular chromosome called a prokaryote contains
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free-floating nuclear material but has no organelles.
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REF: p. 2 b b
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
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bdescribingwhen an isolatedcell absorbsoxygen andusesitto transform nutrients toenergy?
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a. Metabolicabsorption b
b. Communication
c. Secretion
d. Respiration
ANS: D b
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Thecell’s abilityto absorb oxygen is referred to as respiration while its communication ability
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involves maintenanceof a steadydynamicstate, metabolicabsorption provides nutrition, and
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secretion allows for the synthesizing of new substances.
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REF: p. 2 b b
3. A eukaryotic cell is undergoingDNA replication. In which region of thecell would most of the
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genetic information be contained?
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm b
ANS: C b
Theregion ofthecell thatcontainsgeneticmaterial, includingalarge amount ofribonucleic acid,
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most of the DNA, and DNA-bindingproteins, is the nucleolus, which is located within the cell’s
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nucleus. Mitochondria is associated with cellular respiration, while ribosomes are involved with
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protein manufacturing. Cytoplasm is a fluid filling that is a component of the cell.
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REF: p. 2 b b
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