TESTBANK
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Immunology and Serology in Laboratory Medicine
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,Test Bank For
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Immunology And Serology In Laboratory Medicine, 8th Edition By Mary Louise Turgeon
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Chapter 1-27 j
Chapter 01: Highlights Of The Innate And Adaptive Immune Systems
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Multiple Choice j
1. The―Father‖ Of Immunology Is GenerallyConsidered To Be
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a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANSWER: B j
Louis Pasteur Is Generally Considered To Be The ―Father Of Immunology.‖
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DIFFICULTY: COGNITIVE LEVEL: I j j j
2. An Early Form Of Immunization Was Practiced By The
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a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. j
ANSWER: C j
Beginning About 1000 Ad, The Chinese Practiced A Form Of Immunization By Inhaling Dried
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Powders Derived From The Crusts Of Smallpox Lesions.
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DIFFICULTY: COGNITIVE LEVEL: I j j j
3. A Specific Function Of The Immune System Is To
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a. Recognize Self From Nonself. j j j
b. Defend The Body Against Nonself. j j j j
c. Amplify Specific Functions. j j
d. Both A And B. j j j
ANSWER: D j
The Function Of The Immune System Is To Recognize Self From Nonself And Defend The
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Body Against Nonself. Such A System Is Necessary For Survival. The Immune System Also
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Has Nonspecific Effector Mechanisms That Usually Amplify The Specific Functions.
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Nonspecific Components Of The Immune System Include Mononuclear Phagocytes,
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Polymorphonuclear Leukocytes, And Soluble Factors (E.G., Complement).
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DIFFICULTY: COGNITIVE LEVEL: I j j j
4. An Undesirable Consequence Of Immunity Is
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a. Natural Resistance. j
b. Acquired Resistance To Infectious Diseases. j j j j
, c. An Autoimmune Disorder.
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d. Recovery From Infectious Disease. j j j
ANSWER: C j
The Desirable Consequences Of Immunity Include Natural Resistance, Recovery, And
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Acquired Resistance To Infectious Diseases. A Deficiency Or Dysfunction Of The Immune
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System Can Cause Many Disorders. Undesirable Consequences Of Immunity Include Allergy,
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Rejection Of A Transplanted Organ, Or An Autoimmune Disorder.
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DIFFICULTY: COGNITIVE LEVEL: I j j j
5. The Immune System Has Various Distinctive Characteristics Except;
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a. Specificity.
b. Memory.
c. Mobility.
d. Noncooperation Among Different Cells. j j j
ANSWER: D j
The Immune System Is Composed Of A Large, Complex Set Of Widely Distributed Elements,
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With The Distinctive Characteristics Of Specificity, Memory, Mobility, Replicability, And
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Cooperation Among Different Cells Or Cellular Products. Specificity And Memory Are
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Characteristics Of Lymphocytes In The Immune System. Nonspecific Elements Of The Immune
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System Demonstrate Mobility. In Addition, Specific And Nonspecific Cellular Components Of
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The Immune System Can Replicate. Cooperation Is Required For Optimal Functioning, And
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Interaction Involves Specific Cellular Elements, Cell Products, And Nonlymphoid Elements.
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DIFFICULTY: COGNITIVE LEVEL: I j j j
6. Hematopoiesis Occurs In The Yolk Sac During The j j j j j j j
a. Immediate Hours After Conception j j j
b. Second Month Of Gestation. j j j
c. Second Trimester Of Gestation. j j j
d. Periods Of Severe Anemia In Children. j j j j j
ANSWER: A j
The Sites Of Blood Cell Development, Or Hematopoiesis, Follow A Definite Sequence In The
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Embryo And Fetus. Hematopoiesis Occurs In The Yolk Sac During The Second Month Of
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Gestation.
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DIFFICULTY: COGNITIVE LEVEL: Ii j j j
7. The Sequence Of Blood Cell Development In The Embryo And Fetus Is
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a. Yolk Sac, Liver-Spleen, Bone Marrow.
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b. Yolk Sac, Bone Marrow, Liver/Spleen.
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c. Liver-Spleen, Yolk Sac, Bone Marrow. j j j j
d. Bone Marrow, Liver-Spleen, Yolk Sac.
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ANSWER: A j
, The First Blood Cells Are Primitive Red Blood Cells (Erythroblasts; Rbcs) Formed In The
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Islets Of The Yolk Sac During The First 2 To 8 Weeks Of Life. Gradually, The Liver And
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Spleen Replace The Yolk Sac As The Sites Of Blood Cell Development. By The Second
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Month Of Gestation, The Liver Becomes The Major Site Of Hematopoiesis, And Granular
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Types Of Leukocytes Have Made Their Initial Appearance. The Liver And Spleen
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Predominate From About 2 To 5 Months Of Fetal Life. In The Fourth Month Of Gestation,
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Bone Marrow Begins To Produce Blood Cells. After The Fifth Fetal Month, Bone Marrow
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Begins To Assume Its Ultimate Role As The Primary Site Of Hematopoiesis.
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DIFFICULTY: COGNITIVE LEVEL: Ii j j j
8. The Primary Function Of Mature Neutrophils Is
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a. To Reduce Inflammation.
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b. To Lyse Parasites In The Circulatory System.
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c. Antigen Recognition. j
d. Phagocytosis.
ANSWER: D j
Various Phagocytic Cells Continually Circulate Throughout The Blood, Lymph,
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Gastrointestinal System, And Respiratory Tract. When Trauma Occurs, The Neutrophils
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Arrive At The Site Of Injury And Can Be Found In The Initial Exudate In Less Than 1 Hour.
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Monocytes Are Slower In Moving To The Inflammatory Site. Macrophages Resident In The
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Tissues Of The Body Are Already In Place To Deal With An Intruding Agent. Additional
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Macrophages From The Bone Marrow And Other Tissues Can Be Released In Severe
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Infections.
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DIFFICULTY: COGNITIVE LEVEL: Ii j j j
9. Primary Granules, Or Azurophilic Granules, In Neutrophils Contain
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a. Lysozyme.
b. Myeloperoxidase.
c. Lactoferrin.
d. Both A And B. j j j
ANSWER: D j
Granules In The Phagocyte Cytosol Contain Degradatory Enzymes Of Three Types
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1. Primary, Or Azurophilic, Granules Containing Enzymes (E.G., j j j j j j
Lysozyme, Myeloperoxidase)
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2. Secondary, Or Specific, Granules Containing Substances Such As Lactoferrin. j j j j j j j j
3. Tertiary Granules Containing Substances Such As Caspases j j j j j j
DIFFICULTY: COGNITIVE LEVEL: I j j j
10. The Origin Of A Condition When Eosinophils Are Increased In The Circulating Blood Is
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Associated With:
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a. Fungus
b. Parasitic Amoeba j
c. Allergic Reactions j
d. Bacteria
ANSWER: C j
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Immunology and Serology in Laboratory Medicine
j j j j j
,Test Bank For
j j
Immunology And Serology In Laboratory Medicine, 8th Edition By Mary Louise Turgeon
j j j j j j j j j j j
Chapter 1-27 j
Chapter 01: Highlights Of The Innate And Adaptive Immune Systems
j j j j j j j j j
Multiple Choice j
1. The―Father‖ Of Immunology Is GenerallyConsidered To Be
j j j j j j j j
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANSWER: B j
Louis Pasteur Is Generally Considered To Be The ―Father Of Immunology.‖
j j j j j j j j j j
DIFFICULTY: COGNITIVE LEVEL: I j j j
2. An Early Form Of Immunization Was Practiced By The
j j j j j j j j
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. j
ANSWER: C j
Beginning About 1000 Ad, The Chinese Practiced A Form Of Immunization By Inhaling Dried
j j j j j j j j j j j j j
Powders Derived From The Crusts Of Smallpox Lesions.
j j j j j j j j
DIFFICULTY: COGNITIVE LEVEL: I j j j
3. A Specific Function Of The Immune System Is To
j j j j j j j j
a. Recognize Self From Nonself. j j j
b. Defend The Body Against Nonself. j j j j
c. Amplify Specific Functions. j j
d. Both A And B. j j j
ANSWER: D j
The Function Of The Immune System Is To Recognize Self From Nonself And Defend The
j j j j j j j j j j j j j j
Body Against Nonself. Such A System Is Necessary For Survival. The Immune System Also
j j j j j j j j j j j j j j
Has Nonspecific Effector Mechanisms That Usually Amplify The Specific Functions.
j j j j j j j j j j
Nonspecific Components Of The Immune System Include Mononuclear Phagocytes,
j j j j j j j j
Polymorphonuclear Leukocytes, And Soluble Factors (E.G., Complement).
j j j j j j j
DIFFICULTY: COGNITIVE LEVEL: I j j j
4. An Undesirable Consequence Of Immunity Is
j j j j j
a. Natural Resistance. j
b. Acquired Resistance To Infectious Diseases. j j j j
, c. An Autoimmune Disorder.
j j
d. Recovery From Infectious Disease. j j j
ANSWER: C j
The Desirable Consequences Of Immunity Include Natural Resistance, Recovery, And
j j j j j j j j j
Acquired Resistance To Infectious Diseases. A Deficiency Or Dysfunction Of The Immune
j j j j j j j j j j j j
System Can Cause Many Disorders. Undesirable Consequences Of Immunity Include Allergy,
j j j j j j j j j j j
Rejection Of A Transplanted Organ, Or An Autoimmune Disorder.
j j j j j j j j j
DIFFICULTY: COGNITIVE LEVEL: I j j j
5. The Immune System Has Various Distinctive Characteristics Except;
j j j j j j j
a. Specificity.
b. Memory.
c. Mobility.
d. Noncooperation Among Different Cells. j j j
ANSWER: D j
The Immune System Is Composed Of A Large, Complex Set Of Widely Distributed Elements,
j j j j j j j j j j j j j
With The Distinctive Characteristics Of Specificity, Memory, Mobility, Replicability, And
j j j j j j j j j j
Cooperation Among Different Cells Or Cellular Products. Specificity And Memory Are
j j j j j j j j j j j
Characteristics Of Lymphocytes In The Immune System. Nonspecific Elements Of The Immune
j j j j j j j j j j j j
System Demonstrate Mobility. In Addition, Specific And Nonspecific Cellular Components Of
j j j j j j j j j j j
The Immune System Can Replicate. Cooperation Is Required For Optimal Functioning, And
j j j j j j j j j j j j
Interaction Involves Specific Cellular Elements, Cell Products, And Nonlymphoid Elements.
j j j j j j j j j j
DIFFICULTY: COGNITIVE LEVEL: I j j j
6. Hematopoiesis Occurs In The Yolk Sac During The j j j j j j j
a. Immediate Hours After Conception j j j
b. Second Month Of Gestation. j j j
c. Second Trimester Of Gestation. j j j
d. Periods Of Severe Anemia In Children. j j j j j
ANSWER: A j
The Sites Of Blood Cell Development, Or Hematopoiesis, Follow A Definite Sequence In The
j j j j j j j j j j j j j
Embryo And Fetus. Hematopoiesis Occurs In The Yolk Sac During The Second Month Of
j j j j j j j j j j j j j j
Gestation.
j
DIFFICULTY: COGNITIVE LEVEL: Ii j j j
7. The Sequence Of Blood Cell Development In The Embryo And Fetus Is
j j j j j j j j j j j
a. Yolk Sac, Liver-Spleen, Bone Marrow.
j j j j
b. Yolk Sac, Bone Marrow, Liver/Spleen.
j j j j
c. Liver-Spleen, Yolk Sac, Bone Marrow. j j j j
d. Bone Marrow, Liver-Spleen, Yolk Sac.
j j j j
ANSWER: A j
, The First Blood Cells Are Primitive Red Blood Cells (Erythroblasts; Rbcs) Formed In The
j j j j j j j j j j j j j
Islets Of The Yolk Sac During The First 2 To 8 Weeks Of Life. Gradually, The Liver And
j j j j j j j j j j j j j j j j j j
Spleen Replace The Yolk Sac As The Sites Of Blood Cell Development. By The Second
j j j j j j j j j j j j j j j
Month Of Gestation, The Liver Becomes The Major Site Of Hematopoiesis, And Granular
j j j j j j j j j j j j j
Types Of Leukocytes Have Made Their Initial Appearance. The Liver And Spleen
j j j j j j j j j j j j
Predominate From About 2 To 5 Months Of Fetal Life. In The Fourth Month Of Gestation,
j j j j j j j j j j j j j j j j
Bone Marrow Begins To Produce Blood Cells. After The Fifth Fetal Month, Bone Marrow
j j j j j j j j j j j j j j
Begins To Assume Its Ultimate Role As The Primary Site Of Hematopoiesis.
j j j j j j j j j j j j
DIFFICULTY: COGNITIVE LEVEL: Ii j j j
8. The Primary Function Of Mature Neutrophils Is
j j j j j j
a. To Reduce Inflammation.
j j
b. To Lyse Parasites In The Circulatory System.
j j j j j j
c. Antigen Recognition. j
d. Phagocytosis.
ANSWER: D j
Various Phagocytic Cells Continually Circulate Throughout The Blood, Lymph,
j j j j j j j j
Gastrointestinal System, And Respiratory Tract. When Trauma Occurs, The Neutrophils
j j j j j j j j j j
Arrive At The Site Of Injury And Can Be Found In The Initial Exudate In Less Than 1 Hour.
j j j j j j j j j j j j j j j j j j j
Monocytes Are Slower In Moving To The Inflammatory Site. Macrophages Resident In The
j j j j j j j j j j j j j
Tissues Of The Body Are Already In Place To Deal With An Intruding Agent. Additional
j j j j j j j j j j j j j j j
Macrophages From The Bone Marrow And Other Tissues Can Be Released In Severe
j j j j j j j j j j j j j
Infections.
j
DIFFICULTY: COGNITIVE LEVEL: Ii j j j
9. Primary Granules, Or Azurophilic Granules, In Neutrophils Contain
j j j j j j j
a. Lysozyme.
b. Myeloperoxidase.
c. Lactoferrin.
d. Both A And B. j j j
ANSWER: D j
Granules In The Phagocyte Cytosol Contain Degradatory Enzymes Of Three Types
j j j j j j j j j j
1. Primary, Or Azurophilic, Granules Containing Enzymes (E.G., j j j j j j
Lysozyme, Myeloperoxidase)
j j
2. Secondary, Or Specific, Granules Containing Substances Such As Lactoferrin. j j j j j j j j
3. Tertiary Granules Containing Substances Such As Caspases j j j j j j
DIFFICULTY: COGNITIVE LEVEL: I j j j
10. The Origin Of A Condition When Eosinophils Are Increased In The Circulating Blood Is
j j j j j j j j j j j j j
Associated With:
j j
a. Fungus
b. Parasitic Amoeba j
c. Allergic Reactions j
d. Bacteria
ANSWER: C j
