Comprehensive Test Bank for Marieb Human Anatomy &
Physiology, 12th Edition (Hoehn, Haynes, Abbott) – Verified
NCLEX/HESI-Style Questions with Rationales
Chapter/Section: Chapter 1, Section 1.1
An Overview of Anatomy & Physiology
Subtopic: Complementarity of structure and function
Cognitive Level: Recall
Difficulty: Easy
Stem: Which statement best describes the complementarity of
structure and function?
A. Function limits structure in all tissues.
B. Structure and function are unrelated.
C. Structure determines possible function; function influences
structure.
D. Function is always more important than structure.
Correct answer: C
Rationale (correct): Marieb emphasizes that structure
determines function and that function can, over time, influence
structure (e.g., muscle hypertrophy). This bidirectional
complementarity underlies how anatomical form enables
physiological roles. See Chapter 1 discussion of
complementarity of structure and function. Pearson
Why A is wrong: It's too absolute — function does not
universally limit structure; instead structure enables and
constrains functions.
,Why B is wrong: Anatomy and physiology are directly related;
they are not unrelated.
Why D is wrong: The textbook treats structure and function as
interdependent rather than ranking one as inherently more
important.
Teaching point: Anatomy and physiology are inseparable: form
enables function and function shapes form.
A&P002
Chapter / Section / Page–Fig: Chapter 1 — 1.2 The body’s
organization ranges from atoms to the entire organism — Fig.
1.2 / p.8. Pearson
Subtopic: Levels of structural organization
Cognitive Level: Recall
Difficulty: Easy
Stem: Which sequence correctly orders levels of structural
organization from smallest to largest?
A. Cell → Tissue → Organ → Organ system → Molecule
B. Atom → Molecule → Cell → Tissue → Organ → Organ system
→ Organism
C. Organism → Organ system → Organ → Tissue → Cell →
Molecule
D. Molecule → Atom → Cell → Tissue → Organ → Organism
Correct answer: B
Rationale (correct): Marieb outlines the hierarchical
organization from the chemical level (atoms, molecules) to cells,
,tissues, organs, organ systems, and the organism as the correct
progression. This sequence is foundational and is shown in the
chapter’s organization figure. Pearson
Why A is wrong: Molecules come before cells, so the order is
incorrect.
Why C is wrong: It’s simply reversed (largest to smallest).
Why D is wrong: Atoms precede molecules; thus
molecule→atom is incorrect.
Teaching point: Understand the hierarchy: atoms → molecules
→ cells → tissues → organs → organ systems → organism.
A&P003
Chapter / Section / Page–Fig: Chapter 1 — 1.3 What are the
requirements for life? — p.9; Fig. 1.3 (interrelationships).
Pearson Canada School
Subtopic: Necessary life functions
Cognitive Level: Application
Difficulty: Medium
Stem: A patient immobile after surgery shows decreased
muscle mass over two weeks. Which life function best describes
this change?
A. Responsiveness
B. Growth
C. Reproduction
D. Movement (and its role in growth/maintenance)
Correct answer: D
, Rationale (correct): Marieb lists movement and
growth/maintenance among necessary life functions. Loss of
muscle mass from immobility reflects diminished use-related
movement leading to decreased tissue maintenance —
illustrating how movement contributes to growth/maintenance.
Pearson+1
Why A is wrong: Responsiveness refers to reacting to stimuli;
immobility-related atrophy is primarily about movement/use.
Why B is wrong: Growth is increase in size/number of cells;
here the clinical issue is loss (atrophy), not growth.
Why C is wrong: Reproduction concerns making new individuals
and is unrelated to muscle atrophy.
Teaching point: Use and movement support tissue
maintenance; disuse causes atrophy.
A&P004
Chapter / Section / Page–Fig: Chapter 1 — 1.3 Survival Needs
— p.10 (summary). Pearson
Subtopic: Survival needs (oxygen, nutrients, temperature,
water, atmospheric pressure)
Cognitive Level: Recall
Difficulty: Easy
Stem: Which survival need is most directly responsible for
enabling cellular oxidative metabolism?
A. Atmospheric pressure
B. Temperature
Physiology, 12th Edition (Hoehn, Haynes, Abbott) – Verified
NCLEX/HESI-Style Questions with Rationales
Chapter/Section: Chapter 1, Section 1.1
An Overview of Anatomy & Physiology
Subtopic: Complementarity of structure and function
Cognitive Level: Recall
Difficulty: Easy
Stem: Which statement best describes the complementarity of
structure and function?
A. Function limits structure in all tissues.
B. Structure and function are unrelated.
C. Structure determines possible function; function influences
structure.
D. Function is always more important than structure.
Correct answer: C
Rationale (correct): Marieb emphasizes that structure
determines function and that function can, over time, influence
structure (e.g., muscle hypertrophy). This bidirectional
complementarity underlies how anatomical form enables
physiological roles. See Chapter 1 discussion of
complementarity of structure and function. Pearson
Why A is wrong: It's too absolute — function does not
universally limit structure; instead structure enables and
constrains functions.
,Why B is wrong: Anatomy and physiology are directly related;
they are not unrelated.
Why D is wrong: The textbook treats structure and function as
interdependent rather than ranking one as inherently more
important.
Teaching point: Anatomy and physiology are inseparable: form
enables function and function shapes form.
A&P002
Chapter / Section / Page–Fig: Chapter 1 — 1.2 The body’s
organization ranges from atoms to the entire organism — Fig.
1.2 / p.8. Pearson
Subtopic: Levels of structural organization
Cognitive Level: Recall
Difficulty: Easy
Stem: Which sequence correctly orders levels of structural
organization from smallest to largest?
A. Cell → Tissue → Organ → Organ system → Molecule
B. Atom → Molecule → Cell → Tissue → Organ → Organ system
→ Organism
C. Organism → Organ system → Organ → Tissue → Cell →
Molecule
D. Molecule → Atom → Cell → Tissue → Organ → Organism
Correct answer: B
Rationale (correct): Marieb outlines the hierarchical
organization from the chemical level (atoms, molecules) to cells,
,tissues, organs, organ systems, and the organism as the correct
progression. This sequence is foundational and is shown in the
chapter’s organization figure. Pearson
Why A is wrong: Molecules come before cells, so the order is
incorrect.
Why C is wrong: It’s simply reversed (largest to smallest).
Why D is wrong: Atoms precede molecules; thus
molecule→atom is incorrect.
Teaching point: Understand the hierarchy: atoms → molecules
→ cells → tissues → organs → organ systems → organism.
A&P003
Chapter / Section / Page–Fig: Chapter 1 — 1.3 What are the
requirements for life? — p.9; Fig. 1.3 (interrelationships).
Pearson Canada School
Subtopic: Necessary life functions
Cognitive Level: Application
Difficulty: Medium
Stem: A patient immobile after surgery shows decreased
muscle mass over two weeks. Which life function best describes
this change?
A. Responsiveness
B. Growth
C. Reproduction
D. Movement (and its role in growth/maintenance)
Correct answer: D
, Rationale (correct): Marieb lists movement and
growth/maintenance among necessary life functions. Loss of
muscle mass from immobility reflects diminished use-related
movement leading to decreased tissue maintenance —
illustrating how movement contributes to growth/maintenance.
Pearson+1
Why A is wrong: Responsiveness refers to reacting to stimuli;
immobility-related atrophy is primarily about movement/use.
Why B is wrong: Growth is increase in size/number of cells;
here the clinical issue is loss (atrophy), not growth.
Why C is wrong: Reproduction concerns making new individuals
and is unrelated to muscle atrophy.
Teaching point: Use and movement support tissue
maintenance; disuse causes atrophy.
A&P004
Chapter / Section / Page–Fig: Chapter 1 — 1.3 Survival Needs
— p.10 (summary). Pearson
Subtopic: Survival needs (oxygen, nutrients, temperature,
water, atmospheric pressure)
Cognitive Level: Recall
Difficulty: Easy
Stem: Which survival need is most directly responsible for
enabling cellular oxidative metabolism?
A. Atmospheric pressure
B. Temperature
