Page 1 of 822
TEST BANK 5%
Katzung's Basic and Clinical Pharmacol
5% 5% 5% 5%5%
ogy, 16th Edition
5% 5% 5 %
by Todd W. Vanderah, Chapters 1 - 66
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Katzung's Basic and Clinical Pharmacology
, Page 2 of 822
Table of Contents 5% 5%
1. Introduction: The Nature of Drugs & Drug Development & Regulation
5% 5% 5% 5% 5% 5% 5% 5% 5%
2. Drug Receptors & Pharmacodynamics
5% 5% 5%
3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
4. Drug Biotransformation
5%
5. Pharmacogenomics
6. Introduction to Autonomic Pharmacology
5% 5% 5%
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs 5% 5% 5%
8. Cholinoceptor-Blocking Drugs 5%
9. Adrenoceptor Agonists & Sympathomimetic Drugs
5% 5% 5% 5%
10. Adrenoceptor Antagonist Drugs 5% 5%
11. Antihypertensive Agents 5%
12. Vasodilators & the Treatment of Angina Pectoris
5% 5% 5% 5% 5% 5%
13. Drugs Used in Heart Failure
5% 5% 5% 5%
14. Agents Used in Cardiac Arrhythmias
5% 5% 5% 5%
15. Diuretic Agents 5%
16. Histamine, Serotonin, & the Ergot Alkaloids
5% 5% 5% 5% 5%
17. Vasoactive Peptides 5%
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
5% 5% 5% 5% 5% 5% 5%
19. Nitric Oxide
5%
20. Drugs Used in Asthma
5% 5% 5%
21. Introduction to the Pharmacology of CNS Drugs
5% 5% 5% 5% 5% 5%
22. Sedative-Hypnotic Drugs 5%
23. The Alcohols
5%
24. Antiseizure Drugs 5%
25. General Anesthetics5%
26. Local Anesthetics
5%
27. Skeletal Muscle Relaxants
5% 5%
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
5% 5% 5% 5% 5% 5% 5%
29. Antipsychotic Agents & Lithium 5% 5% 5%
30. Antidepressant Agents 5%
31. Opioid Agonists & Antagonists
5% 5% 5%
32. Drugs of Abuse
5% 5%
33. Agents Used in Cytopenias; Hematopoietic Growth Factors
5% 5% 5% 5% 5% 5%
34. Drugs Used in Disorders of Coagulation
5% 5% 5% 5% 5%
35. Agents Used in Dyslipidemia
5% 5% 5%
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-
5% 5% 5%
Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout
5% 5% 5% 5% 5% 5% 5% 5% 5%
37. Hypothalamic & Pituitary Hormones 5% 5% 5%
Katzung's Basic and Clinical Pharmacology
, Page 3 of 822
38. Thyroid & Antithyroid Drugs
5% 5% 5%
39. Adrenocorticosteroids & Adrenocortical Antagonists 5% 5% 5%
40. The Gonadal Hormones & Inhibitors
5% 5% 5% 5%
41. Pancreatic Hormones & Antidiabetic Drugs
5% 5% 5% 5%
42. Agents That Affect Bone Mineral Homeostasis
5% 5% 5% 5% 5%
43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
5% 5% 5% 5% 5% 5% 5%
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones
5% 5% 5% 5% 5% 5%
45. Aminoglycosides & Spectinomycin 5% 5%
46. Sulfonamides, Trimethoprim, & Quinolones 5% 5% 5%
47. Antimycobacterial Drugs 5%
48. Antifungal Agents 5%
49. Antiviral Agents 5%
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants
5% 5% 5% 5% 5% 5%
51. Clinical Use of Antimicrobial Agents
5% 5% 5% 5%
52. Antiprotozoal Drugs 5%
53. Clinical Pharmacology of the Antihelminthic Drugs
5% 5% 5% 5% 5%
54. Cancer Chemotherapy
5%
55. Immunopharmacology
56. Introduction to Toxicology: Occupational & Environmental
5% 5% 5% 5% 5%
57. Heavy Metal Intoxication & Chelators
5% 5% 5% 5%
58. Management of the Poisoned Patient 5% 5% 5% 5%
59. Special Aspects of Perinatal & Pediatric Pharmacology
5% 5% 5% 5% 5% 5%
60. Special Aspects of Geriatric Pharmacology
5% 5% 5% 5%
61. Dermatologic Pharmacology 5%
62. Drugs Used in the Treatment of Gastrointestinal Diseases
5% 5% 5% 5% 5% 5% 5%
63. Therapeutic & Toxic Potential of Over-the-Counter Agents
5% 5% 5% 5% 5% 5%
64. Dietary Supplements & Herbal Medications
5% 5% 5% 5%
65. Rational Prescribing & Prescription Writing
5% 5% 5% 5%
66. Important Drug Interactions & Their Mechanisms
5% 5% 5% 5% 5%
Katzung's Basic and Clinical Pharmacology
, Page 4 of 822
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
1.
A nurse working in radiology administers iodine to a patient who is hav
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
ing a computed tomography (CT) scan. The nurse working on the oncolog
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
y unit administers chemotherapy to patients who have cancer. At the Publi
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
c Health Department, a nurse administers a measles-mumps-
5% 5% 5% 5% 5% 5% 5%
rubella (MMR) vaccine to a 14-month-
5% 5% 5% 5% 5%
old child as a routine immunization. Which branch of pharmacology best d
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
escribes the actions of all three nurses?
5% 5% 5% 5% 5% 5 %
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5
%involved with clinical pharmacology or pharmacotherapeutics, which is a
5% 5% 5% 5% 5% 5% 5% 5% 5%
branch of pharmacology that deals with the uses of drugs to treat, prevent,
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
and diagnose disease. The radiology nurse is administering a drug to help
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5
%diagnose a disease. The oncology nurse is administering a drug to help tre
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
at a disease. Pharmacoeconomics includes any costs involved in drug thera
5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
py.
Pharmacodynamics involves how a drug affects the body and pharmacokine 5% 5% 5% 5% 5% 5% 5% 5% 5%
tics is how the body acts on the body.
5% 5% 5% 5% 5% 5% 5% 5%
2.
A physician has ordered intramuscular (IM) injections of morphine, a n
5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
arcotic, every 4 hours as needed for pain in a motor vehicle accident victi
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
m. The nurse is aware this drug has a high abuse potential. Under what ca
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
tegory would morphine be classified?
5% 5% 5% 5%
A) Schedule I 5%
B) Schedule II 5%
Katzung's Basic and Clinical Pharmacology
TEST BANK 5%
Katzung's Basic and Clinical Pharmacol
5% 5% 5% 5%5%
ogy, 16th Edition
5% 5% 5 %
by Todd W. Vanderah, Chapters 1 - 66
5% 5% 5% 5% 5% 5% 5% 5 %
Katzung's Basic and Clinical Pharmacology
, Page 2 of 822
Table of Contents 5% 5%
1. Introduction: The Nature of Drugs & Drug Development & Regulation
5% 5% 5% 5% 5% 5% 5% 5% 5%
2. Drug Receptors & Pharmacodynamics
5% 5% 5%
3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
4. Drug Biotransformation
5%
5. Pharmacogenomics
6. Introduction to Autonomic Pharmacology
5% 5% 5%
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs 5% 5% 5%
8. Cholinoceptor-Blocking Drugs 5%
9. Adrenoceptor Agonists & Sympathomimetic Drugs
5% 5% 5% 5%
10. Adrenoceptor Antagonist Drugs 5% 5%
11. Antihypertensive Agents 5%
12. Vasodilators & the Treatment of Angina Pectoris
5% 5% 5% 5% 5% 5%
13. Drugs Used in Heart Failure
5% 5% 5% 5%
14. Agents Used in Cardiac Arrhythmias
5% 5% 5% 5%
15. Diuretic Agents 5%
16. Histamine, Serotonin, & the Ergot Alkaloids
5% 5% 5% 5% 5%
17. Vasoactive Peptides 5%
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
5% 5% 5% 5% 5% 5% 5%
19. Nitric Oxide
5%
20. Drugs Used in Asthma
5% 5% 5%
21. Introduction to the Pharmacology of CNS Drugs
5% 5% 5% 5% 5% 5%
22. Sedative-Hypnotic Drugs 5%
23. The Alcohols
5%
24. Antiseizure Drugs 5%
25. General Anesthetics5%
26. Local Anesthetics
5%
27. Skeletal Muscle Relaxants
5% 5%
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
5% 5% 5% 5% 5% 5% 5%
29. Antipsychotic Agents & Lithium 5% 5% 5%
30. Antidepressant Agents 5%
31. Opioid Agonists & Antagonists
5% 5% 5%
32. Drugs of Abuse
5% 5%
33. Agents Used in Cytopenias; Hematopoietic Growth Factors
5% 5% 5% 5% 5% 5%
34. Drugs Used in Disorders of Coagulation
5% 5% 5% 5% 5%
35. Agents Used in Dyslipidemia
5% 5% 5%
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-
5% 5% 5%
Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout
5% 5% 5% 5% 5% 5% 5% 5% 5%
37. Hypothalamic & Pituitary Hormones 5% 5% 5%
Katzung's Basic and Clinical Pharmacology
, Page 3 of 822
38. Thyroid & Antithyroid Drugs
5% 5% 5%
39. Adrenocorticosteroids & Adrenocortical Antagonists 5% 5% 5%
40. The Gonadal Hormones & Inhibitors
5% 5% 5% 5%
41. Pancreatic Hormones & Antidiabetic Drugs
5% 5% 5% 5%
42. Agents That Affect Bone Mineral Homeostasis
5% 5% 5% 5% 5%
43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
5% 5% 5% 5% 5% 5% 5%
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones
5% 5% 5% 5% 5% 5%
45. Aminoglycosides & Spectinomycin 5% 5%
46. Sulfonamides, Trimethoprim, & Quinolones 5% 5% 5%
47. Antimycobacterial Drugs 5%
48. Antifungal Agents 5%
49. Antiviral Agents 5%
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants
5% 5% 5% 5% 5% 5%
51. Clinical Use of Antimicrobial Agents
5% 5% 5% 5%
52. Antiprotozoal Drugs 5%
53. Clinical Pharmacology of the Antihelminthic Drugs
5% 5% 5% 5% 5%
54. Cancer Chemotherapy
5%
55. Immunopharmacology
56. Introduction to Toxicology: Occupational & Environmental
5% 5% 5% 5% 5%
57. Heavy Metal Intoxication & Chelators
5% 5% 5% 5%
58. Management of the Poisoned Patient 5% 5% 5% 5%
59. Special Aspects of Perinatal & Pediatric Pharmacology
5% 5% 5% 5% 5% 5%
60. Special Aspects of Geriatric Pharmacology
5% 5% 5% 5%
61. Dermatologic Pharmacology 5%
62. Drugs Used in the Treatment of Gastrointestinal Diseases
5% 5% 5% 5% 5% 5% 5%
63. Therapeutic & Toxic Potential of Over-the-Counter Agents
5% 5% 5% 5% 5% 5%
64. Dietary Supplements & Herbal Medications
5% 5% 5% 5%
65. Rational Prescribing & Prescription Writing
5% 5% 5% 5%
66. Important Drug Interactions & Their Mechanisms
5% 5% 5% 5% 5%
Katzung's Basic and Clinical Pharmacology
, Page 4 of 822
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
1.
A nurse working in radiology administers iodine to a patient who is hav
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
ing a computed tomography (CT) scan. The nurse working on the oncolog
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
y unit administers chemotherapy to patients who have cancer. At the Publi
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
c Health Department, a nurse administers a measles-mumps-
5% 5% 5% 5% 5% 5% 5%
rubella (MMR) vaccine to a 14-month-
5% 5% 5% 5% 5%
old child as a routine immunization. Which branch of pharmacology best d
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
escribes the actions of all three nurses?
5% 5% 5% 5% 5% 5 %
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5
%involved with clinical pharmacology or pharmacotherapeutics, which is a
5% 5% 5% 5% 5% 5% 5% 5% 5%
branch of pharmacology that deals with the uses of drugs to treat, prevent,
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
and diagnose disease. The radiology nurse is administering a drug to help
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5
%diagnose a disease. The oncology nurse is administering a drug to help tre
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
at a disease. Pharmacoeconomics includes any costs involved in drug thera
5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
py.
Pharmacodynamics involves how a drug affects the body and pharmacokine 5% 5% 5% 5% 5% 5% 5% 5% 5%
tics is how the body acts on the body.
5% 5% 5% 5% 5% 5% 5% 5%
2.
A physician has ordered intramuscular (IM) injections of morphine, a n
5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
arcotic, every 4 hours as needed for pain in a motor vehicle accident victi
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
m. The nurse is aware this drug has a high abuse potential. Under what ca
5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5% 5%
tegory would morphine be classified?
5% 5% 5% 5%
A) Schedule I 5%
B) Schedule II 5%
Katzung's Basic and Clinical Pharmacology