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Summary Endocrine System – Anatomy, Physiology, Hormones & Pathologies | Complete Study Notes for Medical Students

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These comprehensive notes cover the entire human endocrine system, including the anatomy and function of major endocrine glands, hormone types, mechanisms of hormone action, and regulatory feedback loops. The document also explains hormone interactions, the hypothalamic-pituitary axis, and common endocrine disorders like diabetes and thyroid dysfunction. Ideal for medical, nursing, or physiology students, this is a complete guide for mastering endocrine system concepts with clear explanations and integrated clinical insights.

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Uploaded on
September 18, 2025
Number of pages
38
Written in
2025/2026
Type
Summary

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,1-Endocrine System


The endocrine system: a scattered collection of ductless glands and individual cells

that secrete chemical messengers called hormones.


1.1-What is the difference between endocrine and exocrine glands?


• Endocrine glands secrete hormones directly into the bloodstream. These

hormones travel through the blood to target organs or cells. Examples

include the adrenal glands, pituitary gland, and thyroid gland.

• Exocrine glands secrete their products through ducts to an external or

internal surface (not directly into the blood). Examples include sweat

glands, salivary glands, and glands that produce digestive enzymes.


2-What is the function of the endocrine system?

Along with the nervous system, the endocrine system works to help regulate the

body and maintain homeostasis.

3-Comparion table of the nervous and the endocrine system


Nervous System Endocrine System
Initiates responses_____rapidly_______ Initiates responses_____slowly____


__short___-term duration responses __long___-term duration responses


Chemical messengers: Chemical messengers: Hormones
Neurotransmitters

, Act at ______specific______ locations Act at ____diffuse____ locations
determined by axon pathways determined by target cells that can be
anywhere blood reaches


Act over __very short______ distances Act over _long___ distances



4- What are the different types of endocrine glands?


Pure Endocrine Glands


• These glands primarily produce and secrete hormones as their main function.

• They are dedicated endocrine organs with no other major physiological roles.

• Examples discussed in your class include:

o Pituitary gland: Master gland controlling many other endocrine glands.

o Pineal gland: Produces melatonin, regulating sleep-wake cycles.

o Parathyroid glands: Regulate calcium levels in the blood.

o Thyroid gland: Produces thyroid hormones that regulate metabolism.

o Adrenal glands: Produce hormones like cortisol from the adrenal cortex.


Secondary Endocrine Glands


• These glands produce hormones but also have other major functions beyond

hormone secretion.

, • They are not solely endocrine organs; their endocrine role is part of a broader

physiological function.

• Examples from your class include:

o Pancreas: Primarily involved in digestion (exocrine function) but also secretes

insulin and glucagon (endocrine function).

o Gonads (ovaries and testes): Produce sex hormones but also have reproductive

functions.

o Hypothalamus: A neuroendocrine gland that links the nervous system to the

endocrine system by producing releasing hormones (like CRH) that regulate the

pituitary gland.




5-Which are the different types of possible stimuli for endocrine glands?


• Humoral Stimuli:

-Changing levels of ions/nutrients in the blood stimulate the endocrine gland

to release its hormone. The example below shows the parathyroid glands

(the 4 yellow circles) which release their hormone in response to changing

calcium levels in the blood and body.

• Neural Stimuli

-Hormone release is triggered by nerve signals from the nervous system.
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