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USA NU578 Exam 3 – 2025/2026 | 100+ Verified Questions & Correct Answers on Diuretics, Antihypertensives, Renal Function, Cardiovascular Drugs, and Asthma Meds | Nurse Practitioner Pharmacology | USA College of Nursing

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This exam review document provides 100+ fully verified questions and answers for Exam 3 of the NU578 Nurse Practitioner Pharmacology course at USA College of Nursing, designed for the 2025/2026 academic year. It is an essential prep tool for advanced practice nursing students preparing for midterm or final pharmacology exams focused on renal pharmacology, cardiovascular regulation, and respiratory treatments. Key topics covered in this study guide include: Diuretic pharmacology: Mechanism of action and site of action for osmotic, thiazide, loop, and potassium-sparing diuretics (e.g., Mannitol, Furosemide, HCTZ, Spironolactone, Amiloride) Electrolyte imbalances and drug interactions, such as hypokalemia-induced digoxin toxicity and lithium toxicity with hyponatremia Hypertension management: Drug classes including thiazides, loop diuretics, ACE inhibitors, ARBs, beta-blockers, and calcium channel blockers (CCBs) First-line treatments for hypertensive patients by population (e.g., Black, diabetic, stage I/II HTN) Cardiovascular pharmacology: Reflex tachycardia, aldosterone activity, vasodilator effects, renin-angiotensin-aldosterone system (RAAS), and natriuretic peptides Respiratory drugs for asthma and COPD: LABAs, SABAs, inhaled corticosteroids, magnesium sulfate, Heliox, ipratropium, and appropriate rescue therapy Beta-blocker contraindications, CCB precautions, and drug selection in comorbid conditions (e.g., asthma, HF) Pulmonary function testing (e.g., FEV1) and respiratory crisis interventions This document is ideal for: Nurse Practitioner (NP) students enrolled in NU578 or similar pharmacology courses Advanced practice nursing programs (FNP, ACNP, PMHNP) Pharmacology tutors and test-prep facilitators Students preparing for board certification exams (AANP, ANCC) Written in a direct Q&A format with clinical clarity, this resource supports high-level pharmacologic understanding and test readiness in the most challenging therapeutic areas. Keywords: NU578 exam, nurse practitioner pharmacology, diuretics, loop diuretics, thiazides, potassium sparing diuretics, ACE inhibitors, ARBs, beta blockers, calcium channel blockers, digoxin toxicity, HTN management, asthma medications, SABA, LABA, aldosterone, angiotensin II, renal pharmacology, FEV1, respiratory drugs, pharmacology NP exam, USA College of Nursing

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USA NU578 Exam 3 2025/2026 Exam
Questions and Answers | 100% Pass



What is the moa for diuretics? - 🧠 ANSWER ✔✔Affects Maintenance of ecf

volume and composition

What is the Path that urine takes through the nephron - 🧠 ANSWER

✔✔Glomerulus▶️Prox convol tube▶️Loop of Henle: Descrnding

limb▶️Ascending limb▶️DCT▶️Collecting duct

What is the site of action for osmotic diuretics like


Mannitol? - 🧠 ANSWER ✔✔Proximal convoluted tubule


What is the Site of action for Thiazide diuretics like


HCTZ? - 🧠 ANSWER ✔✔Early distal convoluted tubule


What is the (site of action for Potassium sparing diuretics like

, Spironolactone? - 🧠 ANSWER ✔✔Late distal convoluted tubule and

collecting duct (distal nephron)

What is the sote of action for Loop diuretics like


Furosemide? - 🧠 ANSWER ✔✔Loop of Henle


Loop diuretics cause drug toxicity due to increased Na+ excretion. - 🧠

ANSWER ✔✔Lithium excretion is decreased with hyponatremia and

causes lithium toxicity.


Nephron order of diuretic action - 🧠 ANSWER ✔✔Osmotics▶️Loops


▶️Thiazides▶️K+ sparing


PCT (proximal convoluted tubule) - 🧠 ANSWER ✔✔High resorptive

capacity. About 65% of filtered Na+ and Cl resorbed here. Urine is isotonic


Freely permeable to water - 🧠 ANSWER ✔✔Descending limb loop of Henle


Na/K exchange: Na+ reabsorbed, K+ excreted stimulated by - 🧠 ANSWER

✔✔Distal nephron: late DCT/CD


Causes transient deafness - 🧠 ANSWER ✔✔Furosemide


Only diuretic class that is ototoxic - 🧠 ANSWER ✔✔Loop diuretics (pg451)

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