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HESI Pharmacology V1 exam with correct answers.

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HESI Pharmacology V1 exam with correct answers.

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September 16, 2025
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2025/2026
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2023-2026 HESI Pharmacology V1 \|/\\// \|/\\// \|/\\// \|/\\//




exam with correct answers \|/\\// \|/\\// \|/\\//




A nurse is caring for a client with hyperparathyroidism and notes that the client's serum
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




calcium level is 13 mg/dL. Which medication should the nurse prepare to administer as
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




prescribed to the client?1. Calcium chloride \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




2. Calcium gluconate
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3. Calcitonin (Miacalcin)
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4. Large doses of vitamin D - correct answer✔✔3. Calcitonin (Miacalcin)
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




Rationale: \|/\\//




The normal serum calcium level is 8.6 to 10.0 mg/dL. This client is experiencing
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




hypercalcemia. Calcium gluconate and calcium chloride are medications used for the \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




treatment of tetany, which occurs as a result of acute hypocalcemia. In hypercalcemia, large
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doses of vitamin D need to be avoided. Calcitonin, a thyroid hormone, decreases the plasma
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




calcium level by inhibiting bone resorption and lowering the serum calcium concentration.
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Oral iron supplements are prescribed for a 6-year-old child with iron deficiency anemia. The
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nurse instructs the mother to administer the iron with which best food item?
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




1. Milk
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2. Water
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3. Apple juice
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4. Orange juice - correct answer✔✔4. Orange juice
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Rationale: \|/\\//




Vitamin C increases the absorption of iron by the body. The mother should be instructed to
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




administer the medication with a citrus fruit or a juice that is high in vitamin C. Milk may
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//

,affect absorption of the iron. Water will not assist in absorption. Orange juice contains a
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




greater amount of vitamin C than apple juice. \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




Salicylic acid is prescribed for a client with a diagnosis of psoriasis. The nurse monitors the
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




client, knowing that which of the following would indicate the presence of systemic toxicity
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




from this medication? \|/\\// \|/\\//




1. Tinnitus
\|/\\//




2. Diarrhea
\|/\\// \|/\\//




3. Constipation
\|/\\// \|/\\//




4. Decreased Respirations - correct answer✔✔1. Tinnitus
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




Rationale: \|/\\//




Salicylic acid is absorbed readily through the skin, and systemic toxicity (salicylism) can result.
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




Symptoms include tinnitus, dizziness, hyperpnea, and psychological disturbances. Constipation \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




and diarrhea are not associated with salicylism.
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




The camp nurse asks the children preparing to swim in the lake if they have applied
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




sunscreen. The nurse reminds the children that chemical sunscreens are most effective when \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




applied:

1. Immediately before swimming
\|/\\// \|/\\// \|/\\//




2. 15 minutes before exposure to the sun
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




3. Immediately before exposure to the sun
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




4. At least 30 minutes before exposure to the sun - correct answer✔✔4. At least 30 minutes
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




before exposure to the sun \|/\\// \|/\\// \|/\\// \|/\\//




Rationale: \|/\\//




Sunscreens are most effective when applied at least 30 minutes before exposure to the sun so \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




that they can penetrate the skin. All sunscreens should be reapplied after swimming or
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




sweating

,Mafenide acetate (Sulfamylon) is prescribed for the client with a burn injury. When applying \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




the medication, the client complains of local discomfort and burning. Which of the following
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




is the most appropriate nursing action?
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




1. Notifying the registered nurse
\|/\\// \|/\\// \|/\\// \|/\\//




2. Discontinuing the medication
\|/\\// \|/\\// \|/\\//




3. Informing the client that this is normal
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




4. Applying a thinner film than prescribed to the burn site - correct answer✔✔3. Informing
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




the client that this is normal
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




Rationale: \|/\\//




Mafenide acetate is bacteriostatic for gram-negative and gram-positive organisms and is used \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




to treat burns to reduce bacteria present in avascular tissues. The client should be informed
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




that the medication will cause local discomfort and burning and that this is a normal reaction;
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




therefore options 1, 2, and 4 are incorrect \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




The burn client is receiving treatments of topical mafenide acetate (Sulfamylon) to the site of
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




injury. The nurse monitors the client, knowing that which of the following indicates that a
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




systemic effect has occurred?1.Hyperventilation \|/\\// \|/\\// \|/\\//




2.Elevated blood pressure \|/\\// \|/\\// \|/\\//




3.Local pain at the burn site \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




4.Local rash at the burn site - correct answer✔✔1.Hyperventilation \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




Rationale: \|/\\//




Mafenide acetate is a carbonic anhydrase inhibitor and can suppress renal excretion of acid, \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




thereby causing acidosis. Clients receiving this treatment should be monitored for signs of an
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




acid-base imbalance (hyperventilation). If this occurs, the medication should be discontinued \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




for 1 to 2 days. Options 3 and 4 describe local rather than syeffects. An elevated blood
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




pressure may be expected from the pain that occurs with a burn injury. \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//

, Isotretinoin is prescribed for a client with severe acne. Before the administration of this \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




medication, the nurse anticipates that which laboratory test will be prescribed? \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




1. Platelet count
\|/\\// \|/\\//




2. Triglyceride level
\|/\\// \|/\\//




3. Complete blood count
\|/\\// \|/\\// \|/\\// \|/\\//




4. White blood cell count - correct answer✔✔2. Triglyceride level
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




Rationale: \|/\\//




Isotretinoin can elevate triglyceride levels. Blood triglyceride levels should be measured \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




before treatment and periodically thereafter until the effect on the triglycerides has been
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




evaluated. Options 1, 3, and 4 do not need to be monitored specifically during this treatment.
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




A client with severe acne is seen in the clinic and the health care provider (HCP) prescribes
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




isotretinoin. The nurse reviews the client's medication record and would contact the (HCP) if \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




the client is taking which medication?
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




1. Vitamin A
\|/\\// \|/\\//




2. Digoxin (Lanoxin)
\|/\\// \|/\\// \|/\\//




3. Furosemide (Lasix)
\|/\\// \|/\\// \|/\\//




4. Phenytoin (Dilantin) - correct answer✔✔1. Vitamin A
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




Rationale: \|/\\//




Isotretinoin is a metabolite of vitamin A and can produce generalized intensification of \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




isotretinoin toxicity. Because of the potential for increased toxicity, vitamin A supplements
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




should be discontinued before isotretinoin therapy. Options 2, 3, and 4 are not
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




contraindicated with the use of isotretinoin \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




The nurse is applying a topical corticosteroid to a client with eczema. The nurse would
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




monitor for the potential for increased systemic absorption of the medication if the
\|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//




medication were being applied to which of the following body areas? \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\// \|/\\//
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