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APMLE Biochemistry Rapid Review Exam (2024) || Questions & Answers (Graded A+)

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APMLE Biochemistry Rapid Review Exam (2024) || Questions & Answers (Graded A+)

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APMLE Biochemistry Rapid Review Exam (2024) ||
Questions & Answers (Graded A+)

Rate determining Step of glycolysis - (ANSWERS)Phosphofructokinase-1 (PFK-1)

Rate determining Step of gluconeogenesis - (ANSWERS)Fructose-1,6-bisphosphatase

Rate determining Step of TCA (Krebs) - (ANSWERS)Isocitrate Dehydrogenase

Rate determining Step of glycogenesis - (ANSWERS)glycogen synthase

Rate determining Step of of glycogenolysis - (ANSWERS)glycogen phosphorylase

Rate determining Step of HMP Shunt - (ANSWERS)G6PD (glucose-6-phosphate
dehydrogenase)

Rate determining Step of De Novo Pyrimidine Synthesis - (ANSWERS)Carbamoyl Phosphate
Synthase II

Rate determining Step of De Novo PURINE Synthesis - (ANSWERS)Glutamine-
phosphoribosylpyrophosphate (PRPP) amidotransferase

Rate determining Step of Urea Cycle - (ANSWERS)Carbamoyl phosphate synthetase I

Rate determining Step of Fatty Acid Synthesis - (ANSWERS)Acetyl coa carboxylase

Rate determining Step of fatty acid oxidation - (ANSWERS)Carnitine acyltransferase I

Rate determining Step of ketogenesis - (ANSWERS)HMG-coa synthase

Rate determining Step of cholesterol synthesis - (ANSWERS)HMG-coa reductase

Irreversible Steps of the Krebs cycle - (ANSWERS)Citrate Synthase
Isocitrate Dehydrogenase
Alpha-KG dehydrogenase

Name the essential amino acids - (ANSWERS)PVT TIM hall
Phenylalanine
Valine
Threonine
Tryptophan
Isoleucine
Methionine

, APMLE Biochemistry Rapid Review Exam (2024) ||
Questions & Answers (Graded A+)

Histidine
Leucine
Lysine

Name the acidic amino acids - (ANSWERS)aspartate, glutamate
AKA Aspartic ACID and Glutamic ACID

Name the basic amino acids - (ANSWERS)histidine, lysine, arginine
(HIS Lies Are Basic)

Non-essential amino acids - (ANSWERS)alanine, arginine, asparagine, aspartic acid, cysteine,
glutamic acid, glutamine, glycine, proline, serine, tyrosine

Regulators of glycolysis - (ANSWERS)activated by= AMP, Fructose-2,6-Bisphosphate
Inhibited by = ATP, Citrate

Acts on phosphofructose kinase

Regulators of Gluconeogenesis - (ANSWERS)Activated by:
ATP

Inhibited by:
AMP
Fructose-2,6,-diphosphatase

Regulators of TCA cycle - (ANSWERS)Activated by ADP
Inhibited By ATP and NADH

Regulators of glycogenesis - (ANSWERS)activated by = Glucose-6-phosphate, insulin, cortisol
Inhibited by = Epi, glucagon

Regulators of HMP shunt - (ANSWERS)Activated by: NADP+
Inhibited by: NADH

Regulators of de novo pyrmidine synthesis - (ANSWERS)Activated by: ATP and PRPP
UTP inhibits

Regulators of de novo purine synthesis - (ANSWERS)Activated by: none

Inhibited by:
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