Advanced Pathophysiology Practice Questions /
Immunity / Hematology Questions and Answers
2025
Which cells are known as granular lymphocytes?
1. Kupffer cells
2. Microglial cells
3. T cells
4. Natural killer cells - Correct Answer 4. Natural killer cells
1. Kupffer cells found in the liver are examples of macrophages. They are not
known as granular lymphocytes.
2. Microglial cells in the brain are examples of macrophages. They are not
referred to as granular lymphocytes.
3. T cells or T lymphocytes play a vital role in cell-mediated immunity. They
are not known as granular lymphocytes.
4. Natural killer cells act as a first-line of defense in the body and are a part
of the innate immune system. They contain cytoplasmic granules and are
referred to as granular lymphocytes.
pg 202
Where does maturation of T lymphocytes occur?
1. Spleen
2. Bone marrow
3. Thymus gland
4. Lymph nodes - Correct Answer 3. Thymus gland
1. The maturation of B lymphocytes occurs in the spleen.
,Advanced Pathophysiology Practice Questions /
Immunity / Hematology Questions and Answers
2025
2. B lymphocytes mature in the bone marrow.
3. T lymphocytes mature in the thymus glands.
4. B cells, which are also known as B lymphocytes, mature in lymph nodes.
pg 203
Which is the predominant immunoglobulin produced after a host's re-
exposure to an antigen?
1. Immunoglobulin G (IgG)
2. Immunoglobulin A (IgA)
3. Immunoglobulin E (IgE)
4. Immunoglobulin D (IgD) - Correct Answer 1. Immunoglobulin G (IgG)
1. Immunoglobulin G is the predominant immunoglobulin produced after a
host's re-exposure to an antigen. IgG comprises 75% to 80% of the total
serum immunoglobulins.
2. Immunoglobulin A comprises 7% to 15% of the total serum
immunoglobulins. IgA is mainly found in saliva and nasal secretions.
3. Immunoglobulin E is generally present in a low concentration in the blood,
but it increases during allergic reactions.
4. Immunoglobulin D comprises only 1% of total serum immunoglobulins.
pg 204
,Advanced Pathophysiology Practice Questions /
Immunity / Hematology Questions and Answers
2025
A 27-year-old client is pregnant. The blood group of the client and the fetus
are incompatible. Which antibodies produced by the mother against the
fetus's blood cells do not affect the fetus?
1. IgM
2. IgG
3. IgD
4. none of the above - Correct Answer 1. IgM
1. During pregnancy, if the mother and fetus have incompatible blood types,
IgM antibodies will be developed by the mother against the fetus's blood
cells. However, because of the large size of IgM antibodies, they cannot cross
the placenta, and the fetus is protected.
2. During pregnancy, if the mother and fetus have incompatible blood types,
IgM antibodies will be developed by the mother against the fetus's blood
cells. The mother will not produce IgG antibodies in the given situation.
3. During pregnancy, if the mother and fetus have incompatible blood types,
IgM antibodies will be developed by the mother against the fetus's blood
cells. The mother will not produce IgD antibodies in the given situation.
4. The option "none of the above" is incorrect because IgM antibodies are
developed by the mother against the fetus's blood cells in the given
condition.
pg 204
Which immunity is developed by an individual after experiencing illness?
1. Innate immunity
2. Active acquired adaptive immunity
, Advanced Pathophysiology Practice Questions /
Immunity / Hematology Questions and Answers
2025
3. Passive acquired adaptive immunity
4. None of the above - Correct Answer 2. Active acquired adaptive
immunity
1. Innate immunity is the natural mechanism of the body that wards off
foreign bodies as a first line of defense. Mucous producing cells are part of
the body's innate immunity mechanism.
2. Active acquired adaptive immunity is obtained through exposure to an
antigen. It is developed after an individual experiences an illness.
3. Passive acquired adaptive immunity is obtained by an individual after he
or she is given pre-made, fully formed antibodies, such as vaccines, against
an antigen.
4. The option 'none of the above" is incorrect because the immunity
developed by an individual after he or she experiences an illness is active
acquired adaptive immunity.
pg 204
Which is an example of passive acquired adaptive immunity?
1. Newborns receiving immunity through breast milk
2. Individuals becoming immune to chickenpox after infection
3. Individuals becoming immune to measles after infection
4. None of the above - Correct Answer 1. Newborns receiving immunity
through breast milk
1. When a breastfed infant receives fully formed, maternally produced
antibodies through breast milk, the infant acquires passive acquired adaptive
immunity.
Immunity / Hematology Questions and Answers
2025
Which cells are known as granular lymphocytes?
1. Kupffer cells
2. Microglial cells
3. T cells
4. Natural killer cells - Correct Answer 4. Natural killer cells
1. Kupffer cells found in the liver are examples of macrophages. They are not
known as granular lymphocytes.
2. Microglial cells in the brain are examples of macrophages. They are not
referred to as granular lymphocytes.
3. T cells or T lymphocytes play a vital role in cell-mediated immunity. They
are not known as granular lymphocytes.
4. Natural killer cells act as a first-line of defense in the body and are a part
of the innate immune system. They contain cytoplasmic granules and are
referred to as granular lymphocytes.
pg 202
Where does maturation of T lymphocytes occur?
1. Spleen
2. Bone marrow
3. Thymus gland
4. Lymph nodes - Correct Answer 3. Thymus gland
1. The maturation of B lymphocytes occurs in the spleen.
,Advanced Pathophysiology Practice Questions /
Immunity / Hematology Questions and Answers
2025
2. B lymphocytes mature in the bone marrow.
3. T lymphocytes mature in the thymus glands.
4. B cells, which are also known as B lymphocytes, mature in lymph nodes.
pg 203
Which is the predominant immunoglobulin produced after a host's re-
exposure to an antigen?
1. Immunoglobulin G (IgG)
2. Immunoglobulin A (IgA)
3. Immunoglobulin E (IgE)
4. Immunoglobulin D (IgD) - Correct Answer 1. Immunoglobulin G (IgG)
1. Immunoglobulin G is the predominant immunoglobulin produced after a
host's re-exposure to an antigen. IgG comprises 75% to 80% of the total
serum immunoglobulins.
2. Immunoglobulin A comprises 7% to 15% of the total serum
immunoglobulins. IgA is mainly found in saliva and nasal secretions.
3. Immunoglobulin E is generally present in a low concentration in the blood,
but it increases during allergic reactions.
4. Immunoglobulin D comprises only 1% of total serum immunoglobulins.
pg 204
,Advanced Pathophysiology Practice Questions /
Immunity / Hematology Questions and Answers
2025
A 27-year-old client is pregnant. The blood group of the client and the fetus
are incompatible. Which antibodies produced by the mother against the
fetus's blood cells do not affect the fetus?
1. IgM
2. IgG
3. IgD
4. none of the above - Correct Answer 1. IgM
1. During pregnancy, if the mother and fetus have incompatible blood types,
IgM antibodies will be developed by the mother against the fetus's blood
cells. However, because of the large size of IgM antibodies, they cannot cross
the placenta, and the fetus is protected.
2. During pregnancy, if the mother and fetus have incompatible blood types,
IgM antibodies will be developed by the mother against the fetus's blood
cells. The mother will not produce IgG antibodies in the given situation.
3. During pregnancy, if the mother and fetus have incompatible blood types,
IgM antibodies will be developed by the mother against the fetus's blood
cells. The mother will not produce IgD antibodies in the given situation.
4. The option "none of the above" is incorrect because IgM antibodies are
developed by the mother against the fetus's blood cells in the given
condition.
pg 204
Which immunity is developed by an individual after experiencing illness?
1. Innate immunity
2. Active acquired adaptive immunity
, Advanced Pathophysiology Practice Questions /
Immunity / Hematology Questions and Answers
2025
3. Passive acquired adaptive immunity
4. None of the above - Correct Answer 2. Active acquired adaptive
immunity
1. Innate immunity is the natural mechanism of the body that wards off
foreign bodies as a first line of defense. Mucous producing cells are part of
the body's innate immunity mechanism.
2. Active acquired adaptive immunity is obtained through exposure to an
antigen. It is developed after an individual experiences an illness.
3. Passive acquired adaptive immunity is obtained by an individual after he
or she is given pre-made, fully formed antibodies, such as vaccines, against
an antigen.
4. The option 'none of the above" is incorrect because the immunity
developed by an individual after he or she experiences an illness is active
acquired adaptive immunity.
pg 204
Which is an example of passive acquired adaptive immunity?
1. Newborns receiving immunity through breast milk
2. Individuals becoming immune to chickenpox after infection
3. Individuals becoming immune to measles after infection
4. None of the above - Correct Answer 1. Newborns receiving immunity
through breast milk
1. When a breastfed infant receives fully formed, maternally produced
antibodies through breast milk, the infant acquires passive acquired adaptive
immunity.
