Test Bank For Modern Blood Banking & Transfusion Practices 7th Edition By Denise M Harmening [UPDATED 2025!!]

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TESTBANKFORMODERNBLOODBANKING&
vTRANSFUSIONPRACTICES7THEDITIONBY
vDENISEMHARMENING
9780803668881CHAPTER1-29COMPLETE
vGUIDE

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Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple Choicev


Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
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a. Pentose phosphate shunt c. Glycolysis v v


b. Luebering-Rapoport shunt d. Methemoglobin reductase v v v




2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed.
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The unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most a
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ccurate? v


a. The unit of blood should be discarded immediately.
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b. The unit of blood can be returned to inventory.
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c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
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d. The unit of blood must be transfused with 24 hours.
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3. What is the average diameter of a platelet?
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a. 5 to 10 µm v v v c. 1 to 2 µm v v v


b. 2 to 4 µm v v v d. 4 to 6 µm v v v




4. In the normal hemoglobin-
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oxygen dissociation curve, what percentage of oxygen is releasedKto the tissuesKwhen PO2 averages
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4 0 mm Hg?
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a. 75% c. 100%
b. 25% d. 50% v v




5. What factors are known to influence platelet metabolism and function?
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a. Storage temperature c. Platelet count
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b. Initial pH d. All of theKabove
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6. Which of the following red blood cellKmorphologies mayKbeKpresent on the peripheral blood smear as a re
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sult of loss of RBC membrane?
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a. Spherocytes c. Burr cells v


b. Target cells d. Schistocytes
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7. What does the term autologous transfusionKrefer to?
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a. A parent donating blood for his orKher child
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b. An individualKdonating bloodKfor a friend
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c. An individualKdonating blood forKa relative
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d. AnKindividual donating bloodKfor his or her own transfusion v v v v v v v




8. What is theKprimary functionKof hemoglobin?
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a. Iron metabolism c. Oxygen transport
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b. Porphyrin synthesis d. Signal transduction v v v




9. All of the followingKareas of red blood cell biology are crucial for normal erythrocyte survival except:
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a. Cellular metabolism. c. Site of the ABO antigen attachment.
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b. RBC membrane. d. Hemoglobin structure.
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v 10. What is the correct biochemical composition of the RBC membrane?
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a. 52% protein, 40% lipid, 8% carbohydrate v v v v v


b. 40% protein, 8% lipid, 52% carbohydrate v v v v v


c. 8% protein, 52% lipid, 40% carbohydrate
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d. 8% lipid, 40% carbohydrate, 52% protein
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v 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage
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except:
a. Decreased pH. c. Increased ATP level. v v v


b. Loss of red blood cell function. d. Decreased glucose consumption.
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v 12. Which red blood cell preservative has a storage time of 35 days?
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a. ACD c. AS-1
b. CPDA-1 d. CPD

v 13. The RBC membrane is relatively permeable to all of the following except:
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a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. v




14. What percentage of platelets is sequestered in the spleen as functional reserve after being released fromK
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the bone marrow?
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a. 30% c. 10%
b. 50% d. 25%

v 15. What is the major biochemical consideration in plateletKstorage?
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a. Glucose metabolism c. Production of carbon dioxide
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b. Oxygen supply d.K Regulation ofKpHv v v




16. What would the hemoglobin-
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oxygen dissociation curve depict in aKpatient exhibitingKclinical signs of alkalosis?
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a. Normal c. Shift toKthe right v v


b. Shift to the left d.K None of the above
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v 17. Name the main lipid components of a red blood cell membrane.
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a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A v v




v 18. The ABO bloodKgroups were discovered in 1901 by whom?
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a. CharlesKDrew c. Loutit and Mollison v v


b. KarlKLandsteiner d. Edward Lindeman v v




v 19. A standing order of plateletsKwas shipped to your facility by your supplier. It was inadvertently left
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in th e corner of the departmentKuntil discovered 36 hours later. What would the appropriate action be
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for the blood banker?
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a. If the temperature in the box was 22 +/-
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2°C and the platelet swirl seemed OK, it would be OK to accept the unit into
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inventor y. v v


b. The platelets have fallen outside the supplier’s quality assurance. The unit should be
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discarded because the pH has probably dropped too low and platelet activation has be
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en compromised.
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c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
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accept the unit into inventory. v v v v


d. If the platelets appeared OK and passed the platelet swirl test after being placed on
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the agitator, they could be accepted into the inventory.
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20. Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate (2,3-DPG)?
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a. Glycolysis c. Pentose phosphate shunt v v


b. Luebering-Rapoport shunt d. Methemoglobin reductase v v v




21. All of the following are consistent with a "shift to the right" of the hemoglobin-oxygen dissociation
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v curve
except:
a. Increased 2,3-DPG. v

b. 50% O2 saturation to tissues. v v v v


c. Decreased 2,3-DPG. v


d. Decreased hemoglobin affinity for O2. v v v v




v 22. What is the normal platelet count range per cubic millimeter?
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a. 100 to 350 v c. 50,000 to 200,000
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b. 150,000 to 350,000 d. 350,000 to 500,000
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v 23. What cryoprotective agent is added to red blood cells upon freezing?
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a. Dextrose c. Glycerol
b. Adsol d. All of the above v v v v




24. If platelets are to be stored for 5 days on a rotator, what isKtheKoptimal storageKtemperature?
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a. 1°C to 6°C v c. 35°CKto 37°C
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b. 20°C to 24°C v d. 1°C toK10°C
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v 25. What role do platelets play in hemostasis?
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a. Maintenance of vascular integrity v v v


b. Initial arrest of bleeding by platelet plugKformation
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c. Stabilization of the hemostatic plug v v v v


d. All of the above v v v




v 26. Which of the following best describes "integral"Kmembrane proteins?
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a. Reside at the cytoplasmicKsurface of membranev v v v v


b. Span the entire membrane surface v v v v


c. Form the red bloodKcellKcytoskeleton v v v


d. None of the above v v v




v 27. How is stroma-freeKhemoglobin solution prepared?
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a. OutdatedKred blood cells are concentrated, and stroma is removed. v v v v v v v v


b. Outdated red blood cellsKare diluted with saline, and stroma is removed.
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c. OutdatedKred blood cellsKare lysed, and stroma is removed. v v v v v v v


d. None of the above v v v




v 28. What is the normal lifeKspan of an RBC?
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a. 100 days v c. 120 hours v


b. 120 days v d. 2 days v v v




29. Regarding loss of RBC membrane deformability, all of the following are true except:
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a. Increase in ATP level. v v v


b. Decrease in ATP level. v v v




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