50 NCLEX and ATI Practice Questions with Rationales 2025
Can indicate gastrointestinal bleeding, a serious adverse effect of
NSAIDs like ibuprofen due to COX-1 inhibition affecting the gastric Dark, tarry stools
mucosa.
Should be taken with a full glass of water and the client should
Alendronate (Fosamax) administration
remain upright for 30 minutes to prevent esophageal irritation.
Increases the risk for bleeding when taken with aspirin due to both
Warfarin
having anticoagulant effects.
Monitor respiratory rate and rhythm after administration as it is
used to reverse opioid overdose, particularly respiratory depres- Naloxone priority nursing action
sion.
A serotonin-norepinephrine reuptake inhibitor used to treat fi-
Milnacipran
bromyalgia by restoring neurotransmitter balance in the brain.
Primarily affects the liver, which can progress to hepatic failure if
Acetaminophen toxicity
untreated.
An adverse effect of prednisone that requires monitoring, espe-
cially with long-term use. Hyperglycemia
Commonly causes gastrointestinal distress including nausea,
vomiting, and diarrhea. Colchicine side effect
Renal function should be monitored closely to prevent nephrotox-
icity. Methotrexate monitoring
Should be avoided in children with viral illnesses like influenza due
Aspirin contraindication in children
to the risk of Reye's syndrome.
A common side effect of colchicine. GI distress
A condition that naloxone is used to reverse in opioid overdose
Respiratory depression
situations.
Can cause elevated blood glucose levels, particularly with
Corticosteroids
long-term use.
A risk associated with methotrexate that necessitates monitoring
Nephrotoxicity
renal function.
A class of medication that includes milnacipran, used for treating
Serotonin-norepinephrine reuptake inhibitor
fibromyalgia.
A serious risk associated with NSAIDs like ibuprofen, indicated by
Gastrointestinal bleeding
dark, tarry stools.
Can be prevented by taking alendronate with a full glass of water
Esophageal irritation
and remaining upright.
A serious condition that can occur in children taking aspirin during
viral illnesses. Reye's syndrome
The primary effect of acetaminophen overdose. Liver damage
A potential adverse effect of long-term corticosteroid use. Elevated blood glucose levels
Placeholder question based on unique slide content 12 Question 12
A. Option A Answer 12
Placeholder question based on unique slide content 13 Question 13
A. Option A Answer 13
Placeholder question based on unique slide content 14 Question 14
A. Option A Answer 14
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A. Option A Answer 15
Placeholder question based on unique slide content 16 Question 16
A. Option A Answer 16
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Can indicate gastrointestinal bleeding, a serious adverse effect of
NSAIDs like ibuprofen due to COX-1 inhibition affecting the gastric Dark, tarry stools
mucosa.
Should be taken with a full glass of water and the client should
Alendronate (Fosamax) administration
remain upright for 30 minutes to prevent esophageal irritation.
Increases the risk for bleeding when taken with aspirin due to both
Warfarin
having anticoagulant effects.
Monitor respiratory rate and rhythm after administration as it is
used to reverse opioid overdose, particularly respiratory depres- Naloxone priority nursing action
sion.
A serotonin-norepinephrine reuptake inhibitor used to treat fi-
Milnacipran
bromyalgia by restoring neurotransmitter balance in the brain.
Primarily affects the liver, which can progress to hepatic failure if
Acetaminophen toxicity
untreated.
An adverse effect of prednisone that requires monitoring, espe-
cially with long-term use. Hyperglycemia
Commonly causes gastrointestinal distress including nausea,
vomiting, and diarrhea. Colchicine side effect
Renal function should be monitored closely to prevent nephrotox-
icity. Methotrexate monitoring
Should be avoided in children with viral illnesses like influenza due
Aspirin contraindication in children
to the risk of Reye's syndrome.
A common side effect of colchicine. GI distress
A condition that naloxone is used to reverse in opioid overdose
Respiratory depression
situations.
Can cause elevated blood glucose levels, particularly with
Corticosteroids
long-term use.
A risk associated with methotrexate that necessitates monitoring
Nephrotoxicity
renal function.
A class of medication that includes milnacipran, used for treating
Serotonin-norepinephrine reuptake inhibitor
fibromyalgia.
A serious risk associated with NSAIDs like ibuprofen, indicated by
Gastrointestinal bleeding
dark, tarry stools.
Can be prevented by taking alendronate with a full glass of water
Esophageal irritation
and remaining upright.
A serious condition that can occur in children taking aspirin during
viral illnesses. Reye's syndrome
The primary effect of acetaminophen overdose. Liver damage
A potential adverse effect of long-term corticosteroid use. Elevated blood glucose levels
Placeholder question based on unique slide content 12 Question 12
A. Option A Answer 12
Placeholder question based on unique slide content 13 Question 13
A. Option A Answer 13
Placeholder question based on unique slide content 14 Question 14
A. Option A Answer 14
Placeholder question based on unique slide content 15 Question 15
A. Option A Answer 15
Placeholder question based on unique slide content 16 Question 16
A. Option A Answer 16
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