ADVANCED PHARMACOLOGY - CNS DRUGS
LATEST EXAM QUESTIONS AND CORRECT
ANSWERS GRADED A+/
What is a seizure?
Ans: Seizures are initiated by synchronous, high-frequency discharge
from a group of hyper-excitable neurons, called a focus. Seizures are
seen when discharge from a focus spreads to other brain areas, thereby
recruiting normal neurons to discharge abnormally along with the
focus.
Quiz What are the two classifications of seizures?
Ans: 1. Partial - seizure activity invades a very limited part of the brain.
2. Generalized - activity spreads to a large portion of brain
,Quiz What are the 3 categories of Partial Seizures?
Ans: Simple
Complex
Secondarily Generalized
Quiz What are the categories of generalized seizures?
Ans: Tonic-Clonic (Grand Mal)
Absence (Petit Mal)
Atonic
Myoclonic
Status Epiletpticus
Febrile
Quiz How do AED's act?
Ans: 1. Block Na Channels
2. Block Ca Channels
, 3. Block receptors for glutamate (excitatory neurotransmitter)
4. Potentiation of GABA (inhibitory neurotransmitter)
Quiz What is the goal in treating epilepsy?
Ans: Reduce seizures to an extent that enables pt to live a normal or
near normal life. Complete elimination of sz's may not be possible w/o
intolerable side effects.
Quiz AED's can be divided into what 2 groups?
Ans: Traditional AED's
Newer AED's (1999 or later)
Quiz How is monitoring drug levels with epilepsy useful?
Ans: 1. Adjusting dosage
2. Monitoring adherence
3. Determining cause of lost seizure control
4. Identifying cause of toxicity
LATEST EXAM QUESTIONS AND CORRECT
ANSWERS GRADED A+/
What is a seizure?
Ans: Seizures are initiated by synchronous, high-frequency discharge
from a group of hyper-excitable neurons, called a focus. Seizures are
seen when discharge from a focus spreads to other brain areas, thereby
recruiting normal neurons to discharge abnormally along with the
focus.
Quiz What are the two classifications of seizures?
Ans: 1. Partial - seizure activity invades a very limited part of the brain.
2. Generalized - activity spreads to a large portion of brain
,Quiz What are the 3 categories of Partial Seizures?
Ans: Simple
Complex
Secondarily Generalized
Quiz What are the categories of generalized seizures?
Ans: Tonic-Clonic (Grand Mal)
Absence (Petit Mal)
Atonic
Myoclonic
Status Epiletpticus
Febrile
Quiz How do AED's act?
Ans: 1. Block Na Channels
2. Block Ca Channels
, 3. Block receptors for glutamate (excitatory neurotransmitter)
4. Potentiation of GABA (inhibitory neurotransmitter)
Quiz What is the goal in treating epilepsy?
Ans: Reduce seizures to an extent that enables pt to live a normal or
near normal life. Complete elimination of sz's may not be possible w/o
intolerable side effects.
Quiz AED's can be divided into what 2 groups?
Ans: Traditional AED's
Newer AED's (1999 or later)
Quiz How is monitoring drug levels with epilepsy useful?
Ans: 1. Adjusting dosage
2. Monitoring adherence
3. Determining cause of lost seizure control
4. Identifying cause of toxicity
