Inhaled NO - correct answer Pulmonary vasodilator of capillaries surrounding well
ventilated alveoli
Deactivates once it enters the bloodstream
Starting dose: 20ppm
iNO indications - correct answer Increased PVR
Pulmonary HTN
Refractory hypoxemia,
ARDS
Acute pulmonary embolism
COPD
Spontaneous breathing trials & intolerance - correct answer PSV 5/PEEP 5 for 30
minutes and max of 2 hours.
intolerance: RR >35, Sao2 < 90, HR > 140, SBP <90 or > 180, f/VT > 105.
critical opening pressure (Is this the Upper or Lower Inflection Point) - correct answer
the point at which MOST alveoli are open
Lower Inflection Point
Complications of iNO - correct answer Toxic in high concentrations
Toxic byproducts:
MetHb (keep below 2.5%)
NO2 (keep below <2ppm)
Metahemoglobin - correct answer Ability to carry oxygen throughout the body, but
unable to release it. Therefore toxic.
Premature cycling - correct answer Pt continues to have inspiratory effort after ventilator
has cycled off inspiration.
To fix this:
VCV: Increase Vt, decrease Flow rate.
PCV: Increase Ti
Delayed Cyling - correct answer Pt initiates expiratory effort while ventilator still in
inspiratory phase.
To fix:
VCV: Decrease Vt, Increase flow
PCV: Decrease Ti
Diagnosis of brain death - correct answer Increase in PaCo2 by 20 mmhg
PaCo2 > 60
, pH < 7.28
upper inflection point - correct answer the point at which no more alveoli open and no
more tidal volume enters the lungs. This is where you can see beaking occur
PV Loop during mechanical Ventilation
Inspiratory/Expiratory are on which sides - correct answer The loop goes in a
counterclockwise direction. Inspiration is seen on the right side of the loop, while
expiration is seen on the left side. This is inverted for Spontaneous PV Loops.
What muscles are used during Active Spontaneous Breathing - correct answer
Inspiration: scalenus, trapezius, serratus anterior sternocleidomastoid, pectoralis,
diaphragm and external/internal intercostals
Expiration: rectus abdominus, external & internal oblique, transverse abdominal,
serratus, latissimus dorsi
Authorized Acts - correct answer 1.Performing a prescribed procedure below the
dermis.*
2.Intubation beyond the point in the nasal passages where they normally narrow or
beyond the larynx.*
3.Suctioning beyond the point in the nasal passages where they normally narrow or
beyond the larynx.
4.Administering a substance by injection or inhalation.*
5.Administering a prescribed substance by inhalation.
* Needs an order
complications of mechanical ventilation - correct answer Barotrauma, Volutrauma,
Alectotrauma, Biotrauma
Oxygen toxicity
Absorption Atelectasis
VAP
Ventilator-associated pneumonia (VAP) - correct answer Infectious bacteria colonizing
the upper airway, potentially transferring to the LRT via micro aspirations, biofilm in
ETT, pooling of secretions around cuff, impairment of mucocilliary clearance.
VAP diagnosis - correct answer One of:
1.WBC >12K or < 4K
2. Temp: >38 or < 36
AND