1 | Page
PC707 MODULE 1 QUESTIONS AND
ANSWERS
What is prescriptive authority? - correct answer- Legal right to
prescribe drugs
Is the Physicians Desk Reference a reliable source to use
when prescribing drugs? - correct answer- No--it is not
evidence-based and it is not updated
What is the sunshine act? - correct answer- -part of the
affordable care act
-limits providers on accepting gifts from pharmaceutical
companies
-reduces bias
What is pharmacology? - correct answer- -study of the drugs
and their actions and effects on living things
-legal drugs, illegal drugs, prescription drugs, OTC drugs
How does the FDA define drugs that they approve? - correct
answer- -chemicals that have been proved for safety and
efficacy
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What must providers consider when prescribing? - correct
answer- -the dose
-the route of administration
-indications
-side effects of consequence
-adverse effects
-contraindications
-significant drug-drug interactions
-appropriate monitoring
-treatment of side effects if necessary
What is pharmacokinetics? - correct answer- -how drugs move
in the body and what the body does with it
How does pharmacokinetics influence prescribing? - correct
answer- -the route
-the dosage needed
-dosing intervals
What are the 4 aspects of pharmacokinetics? - correct answer-
-absorption
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-distribution
-metabolism
-excretion
What affects bioavailability the most? - correct answer- PO
administration
What is a pro-drug? - correct answer- -a drug that needs to be
metabolized to become "activated"
What is the major organ of metabolism? - correct answer- -
Liver
-Uses enzymes called "CYPs"
-these enzymes can induce or inhibit metabolism
What is protein-binding? - correct answer- -drugs that have a
high affinity for proteins will bind with them and therefore
become unable to bind to receptor sites
-in order to activate receptors they must be free circulating
molecules
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What is the half-life of a drug? - correct answer- -how long it
takes for a drug at its original amount to be reduced by 50%
Why is it important to know the half-life of a drug? - correct
answer- -to help determine dosing intervals to maintain
therapeutic levels
What is the first-pass effect? - correct answer- -alteration of the
drug dose by metabolism before it reaches systemic circulation
-only happens with PO medications
What are the genetic variances of metabolism? - correct
answer- -poor metabolizers (certain enzymes are little to none)
-intermediate metabolizers
-extensive metabolizers (NORMAL)
-ultra-rapid metabolizers (duplicate genes to make extra
enzymes)
What is the primary organ of excretion? - correct answer-
kidneys
What are other methods of excretion? - correct answer- -saliva
PC707 MODULE 1 QUESTIONS AND
ANSWERS
What is prescriptive authority? - correct answer- Legal right to
prescribe drugs
Is the Physicians Desk Reference a reliable source to use
when prescribing drugs? - correct answer- No--it is not
evidence-based and it is not updated
What is the sunshine act? - correct answer- -part of the
affordable care act
-limits providers on accepting gifts from pharmaceutical
companies
-reduces bias
What is pharmacology? - correct answer- -study of the drugs
and their actions and effects on living things
-legal drugs, illegal drugs, prescription drugs, OTC drugs
How does the FDA define drugs that they approve? - correct
answer- -chemicals that have been proved for safety and
efficacy
,2 | Page
What must providers consider when prescribing? - correct
answer- -the dose
-the route of administration
-indications
-side effects of consequence
-adverse effects
-contraindications
-significant drug-drug interactions
-appropriate monitoring
-treatment of side effects if necessary
What is pharmacokinetics? - correct answer- -how drugs move
in the body and what the body does with it
How does pharmacokinetics influence prescribing? - correct
answer- -the route
-the dosage needed
-dosing intervals
What are the 4 aspects of pharmacokinetics? - correct answer-
-absorption
,3 | Page
-distribution
-metabolism
-excretion
What affects bioavailability the most? - correct answer- PO
administration
What is a pro-drug? - correct answer- -a drug that needs to be
metabolized to become "activated"
What is the major organ of metabolism? - correct answer- -
Liver
-Uses enzymes called "CYPs"
-these enzymes can induce or inhibit metabolism
What is protein-binding? - correct answer- -drugs that have a
high affinity for proteins will bind with them and therefore
become unable to bind to receptor sites
-in order to activate receptors they must be free circulating
molecules
, 4 | Page
What is the half-life of a drug? - correct answer- -how long it
takes for a drug at its original amount to be reduced by 50%
Why is it important to know the half-life of a drug? - correct
answer- -to help determine dosing intervals to maintain
therapeutic levels
What is the first-pass effect? - correct answer- -alteration of the
drug dose by metabolism before it reaches systemic circulation
-only happens with PO medications
What are the genetic variances of metabolism? - correct
answer- -poor metabolizers (certain enzymes are little to none)
-intermediate metabolizers
-extensive metabolizers (NORMAL)
-ultra-rapid metabolizers (duplicate genes to make extra
enzymes)
What is the primary organ of excretion? - correct answer-
kidneys
What are other methods of excretion? - correct answer- -saliva
