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MLT ASCP PRACTICE EXAM | COMPREHENSIVE
EXAM QUESTIONS WITH SOLUTIONS
Which of the following helps maintain RBC shape?
a. Membrane phospholipids
b. Cytoskeletal proteins
c. GPI anchor
d. Glycocalyx -correct-answer-b. Cytoskeletal proteins
The glycolipids of the RBC membrane:
a. Provide flexibility
b. Carry RBC antigens
c. Constitute ion channels
d. Attach the cytoskeleton to the lipid layer -correct-answer-b. Carry RBC antigens
Which of the following is an example of a transmembrane or integral membrane
protein?
a. Glycophorin A
b. Ankyrin
c. Spectrin
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d. Actin -correct-answer-
RBC phospholipids are arranged:
a. In a hexagonal lattice
b. In chains beneath a protein exoskeleton
c. In two layers whose composition is asymmetric
d. So that hydrophobic portions are facing the plasma -correct-answer-c. In two
layers whose composition is asymmetric
A hemoglobin molecule is composed of:
a. One heme molecule and four globin chains
b. Ferrous iron, protoporphyrin IX, and a globin chain
c. Protoporphyrin IX and four globin chains
d. Four heme molecules and four globin chains -correct-answer-d. Four heme
molecules and four globin chains
Which of the following forms of hemoglobin molecule has the lowest affinity for
oxygen?
a. Tense
b. Relaxed -correct-answer-a. Tense
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The predominant hemoglobin found in a healthy newborn is:
a. Gower-1
b. Gower-2
c. A
d. F -correct-answer-d. F
Which of the following is a description of the structure of oxidized hemoglobin?
a. Hemoglobin carrying oxygen on heme; synonymous with oxygenated
hemoglobin
b. Hemoglobin with iron in the ferric state (methemoglobin) and not able to carry
oxygen
c. Hemoglobin with iron in the ferric state so that carbon dioxide replaces oxygen
in the heme structure
d. Hemoglobin carrying carbon monoxide; hence "oxidized" refers to the single
oxygen -correct-answer-b. Hemoglobin with iron in the ferric state
(methemoglobin) and not able to carry oxygen
In the quaternary structure of hemoglobin, the globin chains associate into:
a. a tetramers in some cells and B tetramers in others
b. A mixture of a tetramers and B tetramers
c. a dimers and B dimers
d. Two aB dimers -correct-answer-d. Two aB dimers
MLT ASCP PRACTICE EXAM | COMPREHENSIVE
EXAM QUESTIONS WITH SOLUTIONS
Which of the following helps maintain RBC shape?
a. Membrane phospholipids
b. Cytoskeletal proteins
c. GPI anchor
d. Glycocalyx -correct-answer-b. Cytoskeletal proteins
The glycolipids of the RBC membrane:
a. Provide flexibility
b. Carry RBC antigens
c. Constitute ion channels
d. Attach the cytoskeleton to the lipid layer -correct-answer-b. Carry RBC antigens
Which of the following is an example of a transmembrane or integral membrane
protein?
a. Glycophorin A
b. Ankyrin
c. Spectrin
,2|Page
d. Actin -correct-answer-
RBC phospholipids are arranged:
a. In a hexagonal lattice
b. In chains beneath a protein exoskeleton
c. In two layers whose composition is asymmetric
d. So that hydrophobic portions are facing the plasma -correct-answer-c. In two
layers whose composition is asymmetric
A hemoglobin molecule is composed of:
a. One heme molecule and four globin chains
b. Ferrous iron, protoporphyrin IX, and a globin chain
c. Protoporphyrin IX and four globin chains
d. Four heme molecules and four globin chains -correct-answer-d. Four heme
molecules and four globin chains
Which of the following forms of hemoglobin molecule has the lowest affinity for
oxygen?
a. Tense
b. Relaxed -correct-answer-a. Tense
, 3|Page
The predominant hemoglobin found in a healthy newborn is:
a. Gower-1
b. Gower-2
c. A
d. F -correct-answer-d. F
Which of the following is a description of the structure of oxidized hemoglobin?
a. Hemoglobin carrying oxygen on heme; synonymous with oxygenated
hemoglobin
b. Hemoglobin with iron in the ferric state (methemoglobin) and not able to carry
oxygen
c. Hemoglobin with iron in the ferric state so that carbon dioxide replaces oxygen
in the heme structure
d. Hemoglobin carrying carbon monoxide; hence "oxidized" refers to the single
oxygen -correct-answer-b. Hemoglobin with iron in the ferric state
(methemoglobin) and not able to carry oxygen
In the quaternary structure of hemoglobin, the globin chains associate into:
a. a tetramers in some cells and B tetramers in others
b. A mixture of a tetramers and B tetramers
c. a dimers and B dimers
d. Two aB dimers -correct-answer-d. Two aB dimers
