NUR 676 FINAL EXAM QUESTIONS AND 100% CORRECT
ANSWERS UPDATED FOR 2025/2026.
Peptic ulcer disease (PUD) diagnosis and treatment - most common in lesser curvature of
the stomach and duodenum
- endoscopy
PUD antibiotic regimen - use 2-3 antibiotics
0PPI or H2 blocker
clarithromycin-based triple therapy 1 -clarithromycin
-amoxicillin
-PPI
Bismuth-Based Quadruple Therapy -bismuth subsalicylate
-metronidazole
-tetracycline
-PPI or H-2 blocker
clarithromycin-based triple therapy 2 -Used in patients with allergy to PCN
-clarithromycin + metronidazole + PPI
PUD defensive factors mucus, bicarb, blood flow, prostaglandins
prostaglandins in PUD - Stimulate the secretion of mucus and bicarbonate
,- vasodilation
- suppress secretion of gastric acid
PUD with H. pylori treatment Antibiotics + antisecretory agent
Bismuth kill h. pylori
-cause black tongue and stool
ranitidine H2 receptor antagonist
- lowers gastric uice and its hydrogen ion concentration
sucralfate - creates a protective gel barrier that adheres to ulver crater and protect
against acid and pepsin
- only lasts about 6 hours
metronidazole
ulcer prevention (NSAIDs, aspirin) - cause gastric ulcers in part by inhibiting prostaglandin
biosynthesis
- misoprostol acts as a replacement prostaglandin
proton pump inhibitor -prazole
-irreversible inhibition of H+/K+/ATPase (proton pump)
inhibits basal and stimulated acid release
, PPI adverse effects - pneumonia
- fractures
-rebound acid hypersecretion
- hypomagnesemia
- diarrhea
H2 blockers GERD (-tidine)
suppress secretion of gastric acid
GERD diagnosis and treatment - Endoscopy
- PPI
abdominal pain management
colonoscopy prep 1.sodium phosphate
2. sodium picosulfate, magnesium oxide, and citric acid
3. PEG-ELS
laxative schemes 1. bulk-forming
2. surfactant
3. stimulant
4. osmotic
magnesium citrate osmotic laxative
ANSWERS UPDATED FOR 2025/2026.
Peptic ulcer disease (PUD) diagnosis and treatment - most common in lesser curvature of
the stomach and duodenum
- endoscopy
PUD antibiotic regimen - use 2-3 antibiotics
0PPI or H2 blocker
clarithromycin-based triple therapy 1 -clarithromycin
-amoxicillin
-PPI
Bismuth-Based Quadruple Therapy -bismuth subsalicylate
-metronidazole
-tetracycline
-PPI or H-2 blocker
clarithromycin-based triple therapy 2 -Used in patients with allergy to PCN
-clarithromycin + metronidazole + PPI
PUD defensive factors mucus, bicarb, blood flow, prostaglandins
prostaglandins in PUD - Stimulate the secretion of mucus and bicarbonate
,- vasodilation
- suppress secretion of gastric acid
PUD with H. pylori treatment Antibiotics + antisecretory agent
Bismuth kill h. pylori
-cause black tongue and stool
ranitidine H2 receptor antagonist
- lowers gastric uice and its hydrogen ion concentration
sucralfate - creates a protective gel barrier that adheres to ulver crater and protect
against acid and pepsin
- only lasts about 6 hours
metronidazole
ulcer prevention (NSAIDs, aspirin) - cause gastric ulcers in part by inhibiting prostaglandin
biosynthesis
- misoprostol acts as a replacement prostaglandin
proton pump inhibitor -prazole
-irreversible inhibition of H+/K+/ATPase (proton pump)
inhibits basal and stimulated acid release
, PPI adverse effects - pneumonia
- fractures
-rebound acid hypersecretion
- hypomagnesemia
- diarrhea
H2 blockers GERD (-tidine)
suppress secretion of gastric acid
GERD diagnosis and treatment - Endoscopy
- PPI
abdominal pain management
colonoscopy prep 1.sodium phosphate
2. sodium picosulfate, magnesium oxide, and citric acid
3. PEG-ELS
laxative schemes 1. bulk-forming
2. surfactant
3. stimulant
4. osmotic
magnesium citrate osmotic laxative
