ASCP Hematology Review Exam 2026
Questions and Answers 100% Pass
Guaranteed
Name the locations of active marrow in adults: - Correct answer-sternum, skull,
ribs, pelvis, vertebrae
Where does hematopoiesis take place during the first 2 months of gestation? -
Correct answer-yolk sac
Where does the majority of hematopoiesis take place during the 2nd through 7th
month of gestation? - Correct answer-spleen
When does the bone marrow take over hematopoiesis? - Correct answer-after birth
What are the stages in order of the erythrocyte lineage? - Correct answer-
(1)rubriblast, (2)prorubricyte, (3)rubricyte, (4)metarubricyte, (5)reticulocyte,
(6)erytrocyte
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,What are the stages in order of the granulocyte (neutrophil, eosinophil, basophil)
lineage? - Correct answer-(1)myeloblast, (2)promyelocyte, (3)myelocyte,
(4)metamyelocyte, (5)band, (6)segmented (7)eos/baso
What are the stages in order of the macrophage lineage? - Correct answer-
(1)monoblast, (2)promonocyte, (3)monocyte, (4)macrophage
What are the stages in order of the platelet lineage? - Correct answer-
(1)megakaryoblast, (2)promegakaryocyte, (3)megakaryocyte, (4)platelet
What are the stages in order of the lymphocyte lineage? - Correct answer-
(1)lymphoblast, (2)prolymphocyte, (3)lymphocyte
Which growth factors stimulate the erythrocyte lineage? - Correct answer-GM-
CSF, EPO, IL-3
Which growth factors stimulate the granulocyte lineages? - Correct answer-GM-
CSF, IL-3
Which growth factors stimulate the platelet lineage? - Correct answer-GM-CSF,
IL-3, TPO
Which growth factors stimulate the lymphocyte lineage? - Correct answer-IL-2,
IL-4, IL-6, IL-7
Which protein functions in the transport of Fe? - Correct answer-transferrin
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, What is the major storage form of Fe? - Correct answer-ferritin
What is the long-term (H20) insoluble Fe storage form called? - Correct answer-
hemosiderin
Excess Iron is stored where? What does this cause? - Correct answer-tissues and
body organs, hemosiderosis, hemochromatosis
Porphyrias are attributed to? - Correct answer-excessive formation of porphrins
due to blockages in any enzymatic step in the heme synthesis pathway.
Red or port wine colored urine can be seen in which condition related to the build
up of heme precursors? - Correct answer-porphyria
Neuropsychiatirc symptoms are seen when a build up of which precursors occurs?
- Correct answer-early precursors (Delta-aminolevulinic acid/Porphobilinogen)
Cutaneous symptoms such as photo-sensitivity and facial hair are seen when a
build up of which precursors occurs? - Correct answer-later precursors
(uroporphyrinogen/coproporphyrinogen, protoporphyrin/heme)
Synthesis of heme requires what two components? - Correct answer-iron,
protoporphyrin
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Questions and Answers 100% Pass
Guaranteed
Name the locations of active marrow in adults: - Correct answer-sternum, skull,
ribs, pelvis, vertebrae
Where does hematopoiesis take place during the first 2 months of gestation? -
Correct answer-yolk sac
Where does the majority of hematopoiesis take place during the 2nd through 7th
month of gestation? - Correct answer-spleen
When does the bone marrow take over hematopoiesis? - Correct answer-after birth
What are the stages in order of the erythrocyte lineage? - Correct answer-
(1)rubriblast, (2)prorubricyte, (3)rubricyte, (4)metarubricyte, (5)reticulocyte,
(6)erytrocyte
©COPYRIGHT 2025, ALL RIGHTS RESERVE 1
,What are the stages in order of the granulocyte (neutrophil, eosinophil, basophil)
lineage? - Correct answer-(1)myeloblast, (2)promyelocyte, (3)myelocyte,
(4)metamyelocyte, (5)band, (6)segmented (7)eos/baso
What are the stages in order of the macrophage lineage? - Correct answer-
(1)monoblast, (2)promonocyte, (3)monocyte, (4)macrophage
What are the stages in order of the platelet lineage? - Correct answer-
(1)megakaryoblast, (2)promegakaryocyte, (3)megakaryocyte, (4)platelet
What are the stages in order of the lymphocyte lineage? - Correct answer-
(1)lymphoblast, (2)prolymphocyte, (3)lymphocyte
Which growth factors stimulate the erythrocyte lineage? - Correct answer-GM-
CSF, EPO, IL-3
Which growth factors stimulate the granulocyte lineages? - Correct answer-GM-
CSF, IL-3
Which growth factors stimulate the platelet lineage? - Correct answer-GM-CSF,
IL-3, TPO
Which growth factors stimulate the lymphocyte lineage? - Correct answer-IL-2,
IL-4, IL-6, IL-7
Which protein functions in the transport of Fe? - Correct answer-transferrin
©COPYRIGHT 2025, ALL RIGHTS RESERVE 2
, What is the major storage form of Fe? - Correct answer-ferritin
What is the long-term (H20) insoluble Fe storage form called? - Correct answer-
hemosiderin
Excess Iron is stored where? What does this cause? - Correct answer-tissues and
body organs, hemosiderosis, hemochromatosis
Porphyrias are attributed to? - Correct answer-excessive formation of porphrins
due to blockages in any enzymatic step in the heme synthesis pathway.
Red or port wine colored urine can be seen in which condition related to the build
up of heme precursors? - Correct answer-porphyria
Neuropsychiatirc symptoms are seen when a build up of which precursors occurs?
- Correct answer-early precursors (Delta-aminolevulinic acid/Porphobilinogen)
Cutaneous symptoms such as photo-sensitivity and facial hair are seen when a
build up of which precursors occurs? - Correct answer-later precursors
(uroporphyrinogen/coproporphyrinogen, protoporphyrin/heme)
Synthesis of heme requires what two components? - Correct answer-iron,
protoporphyrin
©COPYRIGHT 2025, ALL RIGHTS RESERVE 3
