ASCP MLS Hematology 2025/2026 Exam
Questions and Answers | A+ Score
Assured
Insufficient centrifugation will result in:
A. A false increase in hematocrit (Hct) value
B. A false decrease in Hct value
C. No effect on Hct value
D. All of these options, depending on the patient - 🧠ANSWER ✔✔A.
Insufficient centrifugation does not pack down the
red blood cells; therefore, the Hct, which is the
volume of packed cells, will increase.
Variation in red cell size observed on the peripheral smear is described as:
,A. Anisocytosis
B. Hypochromia
C. Poikilocytosis
D. Pleocytosis - 🧠ANSWER ✔✔A. A mature erythrocyte is approximately 7-
8 μm in
diameter. Variation in normal size is denoted by the
term anisocytosis. Hypochromia is a term that indicates increased central
pallor in erythrocytes, and poikilocytosis denotes variation in red cell shape.
Which of the following is the preferable site for bone marrow aspiration and
biopsy in an adult?
A. Iliac crest
B. Sternum
C. Tibia
D. Spinous processes of a vertebra - 🧠ANSWER ✔✔A. The iliac crest is the
most frequently used site for
,bone marrow aspiration and biopsy. This site is the
safest and most easily accessible, with the bone just
beneath the skin, and neither blood vessels nor
nerves are in the vicinity.
Mean cell volume (MCV) is calculated using the following formula:
A. (Hgb / RBC) × 10
B. (Hct / RBC) × 10
C. (Hct / Hgb) × 100
D. (Hgb / RBC) × 100 - 🧠ANSWER ✔✔B. MCV is the average "volume" of
the red cells. This is
obtained by dividing the Hct or packed cell volume
(PCV) by the red blood cell (RBC) count in millions per
microliter of blood and multiplying by 10. The MCV is
expressed in cubic microns (μm3) or femtoliters (fL).
3
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
, What term describes the change in shape of erythrocytes seen on a
Wright's-stained peripheral blood smear?
A. Poikilocytosis
B. Anisocytosis
C. Hypochromia
D. Polychromasia - 🧠ANSWER ✔✔A. Variation in shape of the erythrocytes
on a peripheral
blood smear is poikilocytosis. Anisocytosis refers to a
change in size. Hypochromia is an increase in central
pallor in erythrocytes. Polychromasia describes the bluish tinge of the
immature erythrocytes (reticulocytes) circulating in the peripheral blood.
Calculate the mean cell hemoglobin concentration (MCHC) using the
following values:
Hgb: 15 g/dL (150 g/L)
Hct: 47 mL/dL (0.47)
Questions and Answers | A+ Score
Assured
Insufficient centrifugation will result in:
A. A false increase in hematocrit (Hct) value
B. A false decrease in Hct value
C. No effect on Hct value
D. All of these options, depending on the patient - 🧠ANSWER ✔✔A.
Insufficient centrifugation does not pack down the
red blood cells; therefore, the Hct, which is the
volume of packed cells, will increase.
Variation in red cell size observed on the peripheral smear is described as:
,A. Anisocytosis
B. Hypochromia
C. Poikilocytosis
D. Pleocytosis - 🧠ANSWER ✔✔A. A mature erythrocyte is approximately 7-
8 μm in
diameter. Variation in normal size is denoted by the
term anisocytosis. Hypochromia is a term that indicates increased central
pallor in erythrocytes, and poikilocytosis denotes variation in red cell shape.
Which of the following is the preferable site for bone marrow aspiration and
biopsy in an adult?
A. Iliac crest
B. Sternum
C. Tibia
D. Spinous processes of a vertebra - 🧠ANSWER ✔✔A. The iliac crest is the
most frequently used site for
,bone marrow aspiration and biopsy. This site is the
safest and most easily accessible, with the bone just
beneath the skin, and neither blood vessels nor
nerves are in the vicinity.
Mean cell volume (MCV) is calculated using the following formula:
A. (Hgb / RBC) × 10
B. (Hct / RBC) × 10
C. (Hct / Hgb) × 100
D. (Hgb / RBC) × 100 - 🧠ANSWER ✔✔B. MCV is the average "volume" of
the red cells. This is
obtained by dividing the Hct or packed cell volume
(PCV) by the red blood cell (RBC) count in millions per
microliter of blood and multiplying by 10. The MCV is
expressed in cubic microns (μm3) or femtoliters (fL).
3
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
, What term describes the change in shape of erythrocytes seen on a
Wright's-stained peripheral blood smear?
A. Poikilocytosis
B. Anisocytosis
C. Hypochromia
D. Polychromasia - 🧠ANSWER ✔✔A. Variation in shape of the erythrocytes
on a peripheral
blood smear is poikilocytosis. Anisocytosis refers to a
change in size. Hypochromia is an increase in central
pallor in erythrocytes. Polychromasia describes the bluish tinge of the
immature erythrocytes (reticulocytes) circulating in the peripheral blood.
Calculate the mean cell hemoglobin concentration (MCHC) using the
following values:
Hgb: 15 g/dL (150 g/L)
Hct: 47 mL/dL (0.47)
