NR565 final
NR 565 / Final Exam: Question Bank (Latest ):
Advanced Pharmacology Fundamentals Chamberlain
What is significant about the proximal convoluted tubule (PCT)? - ANS It is
where the least blood flow occurs, rhe most damage occurs in the PCT
when ischemia happens
What enzyme is obtained from the kidney? - ANS Erythropoieten
angiotensin converting enzyme (ACE) is made where? What does it do? -
ANS It is made in the lungs; to activate angiotensin 1 in the kidneys.
What is most important for the filtration process? - ANS Blood hydrostatic
pressure
What are the functions of the kidney? - ANS Sodium/water removal, waste
removal, hormone production
NR565 final
, 2
NR565 final
What is acute renal failure? - ANS sudden loss of kidney function due to an
illness, Injury, drug, Or toxin that stresses the kidneys. ARF can be
reversible
What is chronic Renal failure? - ANS A long slow process where the kidney
looses its ability to function, it occurs in different stages
What is end stage renal disease? - ANS Irreversible loss of kidney function
What are the types of ARF? - ANS Prerenal, intravenal, post renal
What is the most common cause of ARF? - ANS Pre renal
What happens when pre Renal is not treated? - ANS It can turn into intrinsic/
intrarenal and damage inside
NR565 final
, 3
NR565 final
What is pre-renal failure? - ANS When the damage is before the kidneys due
to decreased blood flow from volume depletion or hypoperfusion
Give examples of volume depletion and hypoperfusion - ANS Too many
diuretics, vomiting and diarrhea, hemorrhage;
Decreased cardiac output due to hf and artheroschlerosis
Explain pathophysiology of pre renal failure - ANS Decreased blood flow
means decreased GFR, decreased GFR means decreased renal blood flow,
then decreased GFR activates RAAS. Angiotensin secretes aldosterone
which increases BP volume
If creatinine is elevated.... - ANS GFR is decreased
What is intra Renal failure? - ANS Its the damage that has occurred inside the
kidney due to:
->Glomerulonephritis
->Rhabdomylosis
NR565 final