NURS 5334 PHARM FINAL EXAM LATEST 2024 ACTUAL EXAM 100 QUESTIONS AND CORRECT DETAILED
ANSWERS
Paroxetine - (answer) An SSRI that may cause erectile dysfunction.
Ethosuximide Monitoring - (answer) Patients should be monitored for blood dyscrasias which are
uncommon but possible.
Lamotrigine and OCPs Interaction - (answer) OCPs can reduce lamotrigine levels, requiring an increase
in the dose of lamotrigine.
Tricyclic Antidepressants Caution - (answer) Should be prescribed cautiously in patients with CAD.
Onset of Action Symptoms for SSRIs - (answer) Patients may feel a bit of nausea, which resolves in
about 1 week.
Pediatric Dosing Information - (answer) There is a lack of evidence-based literature on the safe and
effective use of medications in children.
Neonates and Protein-Bound Drugs - (answer) Protein binding is decreased in neonates, increasing the
amount of free drug available.
Adult Renal Function Age - (answer) Adult levels of renal function are achieved at 12 months.
Beers List - (answer) A list that identifies drugs with a high likelihood of causing adverse effects in the
elderly.
Gastric Acidity in Pediatric Patients - (answer) Gastric acidity does not reach adult values for 2 years.
Complications to Drug Therapy in the Elderly - (answer) Include altered pharmacokinetics, multiple
and severe illnesses, multiple-drug therapy, and poor adherence.
Altered Absorption in the Elderly - (answer) May result in a delay in drug response.
,NURS 5334 PHARM FINAL EXAM LATEST 2024 ACTUAL EXAM 100 QUESTIONS AND CORRECT DETAILED
ANSWERS
Factors Altering Drug Distribution in the Elderly - (answer) Include increased body fat, decreased
percentage of lean body mass, decreased total body water, and reduced concentration of serum
albumin.
Adverse Drug Reactions in the Elderly - (answer) The most important cause of adverse drug reactions
in the elderly is polypharmacy.
Bupropion - (answer) An alternative medication that can be added to help with erectile dysfunction
caused by SSRIs.
Increased Seizure Activity with Ethosuximide - (answer) Ethosuximide can induce seizures, so
increased seizure activity should be monitored.
Renal Dysfunction Monitoring - (answer) Patients on ethosuximide should be monitored for renal
dysfunction.
Weight Gain with OCPs - (answer) OCPs can cause weight gain, which may be a concern for patients
taking lamotrigine.
Hepatotoxicity with Ethosuximide - (answer) Hepatotoxicity is a potential risk, but uncommon.
Contraceptive Failure with OCPs - (answer) OCPs may lead to contraceptive failure when interacting
with lamotrigine.
Insomnia with SSRIs - (answer) Patients may experience insomnia for a week after starting SSRIs.
FDA and Pediatric Dosing - (answer) The FDA does not require pediatric dosing information for all
medications.
,NURS 5334 PHARM FINAL EXAM LATEST 2024 ACTUAL EXAM 100 QUESTIONS AND CORRECT DETAILED
ANSWERS
Free Drug Availability in Neonates - (answer) Decreased protein binding in neonates increases the
amount of free drug available.
Proper index of renal function in the elderly - (answer) Creatinine clearance or GFR.
Factors underlying increase in adverse reactions in geriatric population - (answer) Polypharmacy,
severe illness, multiple pathologies, greater use of drugs that have a low therapeutic index, inadequate
supervision, poor patient adherence.
Maximum amount of Sumatriptan that can be taken in 1 day - (answer) 200 mg.
Properties determining anesthetic penetration of axon membrane - (answer) Molecular size, lipid
solubility, degree of ionization at tissue pH.
Medication that will not cause rebound headaches from overuse - (answer) Propranolol.
Best option for menstrual migraine - (answer) Low dose estrogen about 3 days prior to menses.
Food that can trigger migraines - (answer) Hot dog.
Medication that is a Serotonin 1B1D receptor agonist - (answer) Sumatriptan.
Side effect of Butterbur in migraine therapy - (answer) Liver damage.
Three main classes of opioid receptors - (answer) Mu, Kappa, Delta.
Reversal of effects caused by opioid agonists - (answer) Naloxone.
Medications used to treat OIC - (answer) Naloxegol, Methylinaltrexone, Lubiprostone.
, NURS 5334 PHARM FINAL EXAM LATEST 2024 ACTUAL EXAM 100 QUESTIONS AND CORRECT DETAILED
ANSWERS
Definition of tolerance - (answer) Increased doses of a med needed to obtain the same response.
Medication used for opioid abuse - (answer) Naltrexone.
Euphoria induced by morphine - (answer) An exaggerated sense of well-being caused by the activation
of mu receptors.
Medication given nasally for migraines - (answer) Butorphanol.
Mechanism of NSAIDs - (answer) Inhibition of the cyclo-oxygenase enzyme.
Second generation Cox 2 inhibitors - (answer) Suppress inflammation and cause less risk for gastric
ulceration than Cox 1.
Glucocorticoids - (answer) Medications that should not be given with ASA include Glucocorticoids.
Acetaminophen overdose treatment - (answer) The medication given for acetaminophen overdose is
Acetylcysteine.
Nonendocrine therapeutic uses for glucocorticoids - (answer) Uses include RA, SLE, IBS, Bursitis, OA,
Gout, and Disorders of the eye.
Prolonged use of glucocorticoids - (answer) The danger of prolonged use is adrenal insufficiency.
Methotrexate toxicities - (answer) Methotrexate can cause fatal toxicities of bone marrow, liver,
kidneys, lungs, hemorrhagic enteritis, and GI perforation.
Etanercept monitoring - (answer) Jane should be checked for TB yearly.
ANSWERS
Paroxetine - (answer) An SSRI that may cause erectile dysfunction.
Ethosuximide Monitoring - (answer) Patients should be monitored for blood dyscrasias which are
uncommon but possible.
Lamotrigine and OCPs Interaction - (answer) OCPs can reduce lamotrigine levels, requiring an increase
in the dose of lamotrigine.
Tricyclic Antidepressants Caution - (answer) Should be prescribed cautiously in patients with CAD.
Onset of Action Symptoms for SSRIs - (answer) Patients may feel a bit of nausea, which resolves in
about 1 week.
Pediatric Dosing Information - (answer) There is a lack of evidence-based literature on the safe and
effective use of medications in children.
Neonates and Protein-Bound Drugs - (answer) Protein binding is decreased in neonates, increasing the
amount of free drug available.
Adult Renal Function Age - (answer) Adult levels of renal function are achieved at 12 months.
Beers List - (answer) A list that identifies drugs with a high likelihood of causing adverse effects in the
elderly.
Gastric Acidity in Pediatric Patients - (answer) Gastric acidity does not reach adult values for 2 years.
Complications to Drug Therapy in the Elderly - (answer) Include altered pharmacokinetics, multiple
and severe illnesses, multiple-drug therapy, and poor adherence.
Altered Absorption in the Elderly - (answer) May result in a delay in drug response.
,NURS 5334 PHARM FINAL EXAM LATEST 2024 ACTUAL EXAM 100 QUESTIONS AND CORRECT DETAILED
ANSWERS
Factors Altering Drug Distribution in the Elderly - (answer) Include increased body fat, decreased
percentage of lean body mass, decreased total body water, and reduced concentration of serum
albumin.
Adverse Drug Reactions in the Elderly - (answer) The most important cause of adverse drug reactions
in the elderly is polypharmacy.
Bupropion - (answer) An alternative medication that can be added to help with erectile dysfunction
caused by SSRIs.
Increased Seizure Activity with Ethosuximide - (answer) Ethosuximide can induce seizures, so
increased seizure activity should be monitored.
Renal Dysfunction Monitoring - (answer) Patients on ethosuximide should be monitored for renal
dysfunction.
Weight Gain with OCPs - (answer) OCPs can cause weight gain, which may be a concern for patients
taking lamotrigine.
Hepatotoxicity with Ethosuximide - (answer) Hepatotoxicity is a potential risk, but uncommon.
Contraceptive Failure with OCPs - (answer) OCPs may lead to contraceptive failure when interacting
with lamotrigine.
Insomnia with SSRIs - (answer) Patients may experience insomnia for a week after starting SSRIs.
FDA and Pediatric Dosing - (answer) The FDA does not require pediatric dosing information for all
medications.
,NURS 5334 PHARM FINAL EXAM LATEST 2024 ACTUAL EXAM 100 QUESTIONS AND CORRECT DETAILED
ANSWERS
Free Drug Availability in Neonates - (answer) Decreased protein binding in neonates increases the
amount of free drug available.
Proper index of renal function in the elderly - (answer) Creatinine clearance or GFR.
Factors underlying increase in adverse reactions in geriatric population - (answer) Polypharmacy,
severe illness, multiple pathologies, greater use of drugs that have a low therapeutic index, inadequate
supervision, poor patient adherence.
Maximum amount of Sumatriptan that can be taken in 1 day - (answer) 200 mg.
Properties determining anesthetic penetration of axon membrane - (answer) Molecular size, lipid
solubility, degree of ionization at tissue pH.
Medication that will not cause rebound headaches from overuse - (answer) Propranolol.
Best option for menstrual migraine - (answer) Low dose estrogen about 3 days prior to menses.
Food that can trigger migraines - (answer) Hot dog.
Medication that is a Serotonin 1B1D receptor agonist - (answer) Sumatriptan.
Side effect of Butterbur in migraine therapy - (answer) Liver damage.
Three main classes of opioid receptors - (answer) Mu, Kappa, Delta.
Reversal of effects caused by opioid agonists - (answer) Naloxone.
Medications used to treat OIC - (answer) Naloxegol, Methylinaltrexone, Lubiprostone.
, NURS 5334 PHARM FINAL EXAM LATEST 2024 ACTUAL EXAM 100 QUESTIONS AND CORRECT DETAILED
ANSWERS
Definition of tolerance - (answer) Increased doses of a med needed to obtain the same response.
Medication used for opioid abuse - (answer) Naltrexone.
Euphoria induced by morphine - (answer) An exaggerated sense of well-being caused by the activation
of mu receptors.
Medication given nasally for migraines - (answer) Butorphanol.
Mechanism of NSAIDs - (answer) Inhibition of the cyclo-oxygenase enzyme.
Second generation Cox 2 inhibitors - (answer) Suppress inflammation and cause less risk for gastric
ulceration than Cox 1.
Glucocorticoids - (answer) Medications that should not be given with ASA include Glucocorticoids.
Acetaminophen overdose treatment - (answer) The medication given for acetaminophen overdose is
Acetylcysteine.
Nonendocrine therapeutic uses for glucocorticoids - (answer) Uses include RA, SLE, IBS, Bursitis, OA,
Gout, and Disorders of the eye.
Prolonged use of glucocorticoids - (answer) The danger of prolonged use is adrenal insufficiency.
Methotrexate toxicities - (answer) Methotrexate can cause fatal toxicities of bone marrow, liver,
kidneys, lungs, hemorrhagic enteritis, and GI perforation.
Etanercept monitoring - (answer) Jane should be checked for TB yearly.