GEORGETTE MODULE 1 & 2 EXAM 2025 QUESTIONS AND ANSWERS

GEORGETTE MODULE 1 & 2 EXAM 2025
QUESTIONS AND ANSWERS




Lithium level - ANS 0.6-1.2


Lithium toxicity level - ANS greater than or equal to 1.5


what is the gold standard for treating manic episodes? - ANS Lithium


What drug has evidence of anti-suicidal effects for bipolar disorder? - ANS Lithium


baseline labs to collect in order to R/O medical diagnoses prior to giving Lithium - ANS TSH
(r/o bipolar)
Creatinine (0.6-1.2)
BUN (10-20)
Pregnancy test
ECG if greater than 50 (inverted T-waves)


All psychotropics should have what test prior to giving for child-bearing age? -
ANS pregnancy test


what is considered child-bearing age? - ANS 12-51
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, SE of Lithium? (endocrine) - ANS HYPOthyroidism


SE of Lithium? (CNS) - ANS **course hand tremors w/ toxicity


SE of Lithium? (dermatological) - ANS Maculopapular rash


SE of Lithium? (GI) - ANS diarrhea, vomiting, cramp, anorexia
**imp. because these become severe w/ toxicity


SE of Lithium? (Renal) - ANS diabetes insipidus (polyuria r/t polydipsia)


SE of Lithium? (Cardiac) - ANS T-wave inversions


SE of Lithium? (Hematologic) - ANS leukocytosis (increased WBC)


Hypertensive Crisis occurs when..... - ANS MAOIs are taken in conjunction w/ foods
containing TYRAMINE (dietary precursor of NE)


Hypertensive crisis is _____-__________ and cannot be reversed unless..... - ANS life-
threatening & cannot be reversed unless more MAO is produced by the body


Hypertensive crisis & death can occur when MAOIs are taken in conjunction with which types of
meds?? - ANS ***Meperidine
***Stimulants/other sympathomimetics
Decongestants/TCA/SGA/St. Johns Wort/L-tryptophan


Symptoms of Hypertensive crisis include - ANS sudden explosive-like HA in OCCIPITAL region
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Fever**



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, Treatment of Hypertensive Crisis - ANS 1. d/c offending agent (MAOI)
2. administer PHENTOLAMINE
3. Stabilize fever


medication to reverse hypertensive crisis w/ MAOI? - ANS Phentolamine****


List of common MAOIs (don't need to memorize, just know what it looks like) -
ANS Isocarboxazid (Marplan)
Phenelzine (Nardil)
Selegiline (Emsam)
Tranylcypromine (Parnate)


Teratogenic risks of common psych meds (Benzo, Carbamazepine, Lithium, Depakote) -
ANS Benzo: floppy baby & cleft palate
Carbamazepine: neural tube defect
Lithium: Epstein's anomaly & Congenital heart defects (esp. 1st trimester)
Depakote: Neural tube defects (spec. spina bifida)


Lamicatal main SE - ANS Steven Johnson's Syndrome*** (SE below, KNOW)
- Fever**
- Sore throat (may feel like burning**
- Facial/tongue swelling**
- Skin sloughing***
- Prodromal HA, malaise, Arthralgia, painful mucous membranes may occur BEFORE rash


Valproic Acid/Divalproex Sodium aka Depakote main SE - ANS Hepatotoxicity**
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Pancreatitis**



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, Carbamazepine (Tegretol) main SE - ANS Agranulocytosis***
Aplastic Anemia***
Steven-Johnson's*** (mainly Asians HLAB-1502 allele)


Aplastic Anemia s/s - ANS pallor, fatigue, HA, fever, nose bleeds, bleeding gums, skin rash,
SOB


Carbamazepine when to d/c - ANS WBC 2000-3000
ANC < 1000
Rash/Steven Johnson's
Or s/s of aplastic anemia or agranulocytosis


What to test prior to prescribing Cabamazepine?? - ANS HLA-B 1502 allele in Asians d/t
Steven's Johnson Syndrome


Clozapine main SE - ANS Risk for NEUTROPENIA --> monitor for s/s of infection***


Neutropenia is monitored only by... - ANS ANC


when to d/c Clozapine? - ANS ANC <1000
WBC 2000-3000


Check ____ before starting female of childbearing age (12-51yr) on psychotropic med -
ANS HCG
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