Test Bank –
Immunology And Serology In Laboratory Medicine
By Turgeon
8th edition
,Table of content
Part i: basic immunologic mechanisms
1. Foundations of innate and adaptive immune systems
2. Soluble mediators of the immune system
3. Antigens and antibodies
4. Cellular activities and clinical disorders of innate and adaptive immunity
part ii: the theory of immunologic and serologic procedures
5. Basic safety in the immunology-serology laboratory
6. Basic quality control and quality assurance practices
7. Basic serologic laboratory: techniques and clinical applications
8. Precipitation and particle agglutination methods
9. Electrophoresis techniques and chromatography
10. Labeling techniques in immunoassay
11. Flow cytometry
12. Molecular laboratory techniques
part iii: immunologic manifestations of infectious diseases
13. Infectious diseases: overview and torch diseases
14. Streptococcal infections
15. Syphilis
16. Vector-borne diseases
17. Infectious mononucleosis
18. Viral hepatitis
part iv: immune disorders
19. Primary and acquired immunodeficiency syndromes
20. Hypersensitivity reactions
21. Plasma cell neoplasms and other diseases with paraproteins
22. Tolerance, autoimmunity, and autoimmune disorders
23. Systemic lupus erythematosus
24. Rheumatoid arthritis
part v: transplantation and tumor immunology
25. Transplantation: human leukocyte antigens, solid organ, tissues, and hematopoietic stem
cells
26. Tumor immunology and applications of massive parallel sequencing/next-generation
sequencing
part vi: vaccines
27. Vaccines: development and applications
,Test bank for
immunology and serology in laboratory medicine, 8th edition by mary louise turgeon
Chapter 1-27
Chapter 01: highlights of the innate and adaptive immune systems
Multiple choice
1. The ―father‖ of immunology is generally considered to be
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS; b
Louis pasteur is generally considered to be the ―father of immunology.‖
Dif: cognitive level: i
2. An early form of immunization was practiced by the
a. Romans.
b. Greeks.
c. Chinese.
d. Native americans.
ANS; c
Beginning about 1000 ad, the chinese practiced a form of immunization by inhaling dried
powders derived from the crusts of smallpox lesions.
Dif: cognitive level: i
3. A specific function of the immune system is to
a. Recognize self from nonself.
b. Defend the body against nonself.
c. Amplify specific functions.
d. Both a and b.
ANS; d
The function of the immune system is to recognize self from nonself and defend the body
against nonself. Such a system is necessary for survival. The immune system also has
nonspecific effector mechanisms that usually amplify the specific functions. Nonspecific
components of the immune system include mononuclear phagocytes, polymorphonuclear
leukocytes, and soluble factors (e.g., complement).
Dif: cognitive level: i
4. An undesirable consequence of immunity is
a. Natural resistance.
b. Acquired resistance to infectious diseases.
, c. An autoimmune disorder.
d. Recovery from infectious disease.
ANS; c
The desirable consequences of immunity include natural resistance, recovery, and acquired
resistance to infectious diseases. A deficiency or dysfunction of the immune system can cause
many disorders. Undesirable consequences of immunity include allergy, rejection of a
transplanted organ, or an autoimmune disorder.
Dif: cognitive level: i
5. The immune system has various distinctive characteristics except;
a. Specificity.
b. Memory.
c. Mobility.
d. Noncooperation among different cells.
ANS; d
The immune system is composed of a large, complex set of widely distributed elements, with
the distinctive characteristics of specificity, memory, mobility, replicability, and cooperation
among different cells or cellular products. Specificity and memory are characteristics of
lymphocytes in the immune system. Nonspecific elements of the immune system demonstrate
mobility. In addition, specific and nonspecific cellular components of the immune system can
replicate. Cooperation is required for optimal functioning, and interaction involves specific
cellular elements, cell products, and nonlymphoid elements.
Dif: cognitive level: i
6. Hematopoiesis occurs in the yolk sac during the
a. Immediate hours after conception
b. Second month of gestation.
c. Second trimester of gestation.
d. Periods of severe anemia in children.
ANS; a
The sites of blood cell development, or hematopoiesis, follow a definite sequence in the
embryo and fetus. Hematopoiesis occurs in the yolk sac during the second month of gestation.
Dif: cognitive level: ii
7. The sequence of blood cell development in the embryo and fetus is
a. Yolk sac, liver-spleen, bone marrow.
b. Yolk sac, bone marrow, liver/spleen.
c. Liver-spleen, yolk sac, bone marrow.
d. Bone marrow, liver-spleen, yolk sac.
ANS; a
Immunology And Serology In Laboratory Medicine
By Turgeon
8th edition
,Table of content
Part i: basic immunologic mechanisms
1. Foundations of innate and adaptive immune systems
2. Soluble mediators of the immune system
3. Antigens and antibodies
4. Cellular activities and clinical disorders of innate and adaptive immunity
part ii: the theory of immunologic and serologic procedures
5. Basic safety in the immunology-serology laboratory
6. Basic quality control and quality assurance practices
7. Basic serologic laboratory: techniques and clinical applications
8. Precipitation and particle agglutination methods
9. Electrophoresis techniques and chromatography
10. Labeling techniques in immunoassay
11. Flow cytometry
12. Molecular laboratory techniques
part iii: immunologic manifestations of infectious diseases
13. Infectious diseases: overview and torch diseases
14. Streptococcal infections
15. Syphilis
16. Vector-borne diseases
17. Infectious mononucleosis
18. Viral hepatitis
part iv: immune disorders
19. Primary and acquired immunodeficiency syndromes
20. Hypersensitivity reactions
21. Plasma cell neoplasms and other diseases with paraproteins
22. Tolerance, autoimmunity, and autoimmune disorders
23. Systemic lupus erythematosus
24. Rheumatoid arthritis
part v: transplantation and tumor immunology
25. Transplantation: human leukocyte antigens, solid organ, tissues, and hematopoietic stem
cells
26. Tumor immunology and applications of massive parallel sequencing/next-generation
sequencing
part vi: vaccines
27. Vaccines: development and applications
,Test bank for
immunology and serology in laboratory medicine, 8th edition by mary louise turgeon
Chapter 1-27
Chapter 01: highlights of the innate and adaptive immune systems
Multiple choice
1. The ―father‖ of immunology is generally considered to be
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS; b
Louis pasteur is generally considered to be the ―father of immunology.‖
Dif: cognitive level: i
2. An early form of immunization was practiced by the
a. Romans.
b. Greeks.
c. Chinese.
d. Native americans.
ANS; c
Beginning about 1000 ad, the chinese practiced a form of immunization by inhaling dried
powders derived from the crusts of smallpox lesions.
Dif: cognitive level: i
3. A specific function of the immune system is to
a. Recognize self from nonself.
b. Defend the body against nonself.
c. Amplify specific functions.
d. Both a and b.
ANS; d
The function of the immune system is to recognize self from nonself and defend the body
against nonself. Such a system is necessary for survival. The immune system also has
nonspecific effector mechanisms that usually amplify the specific functions. Nonspecific
components of the immune system include mononuclear phagocytes, polymorphonuclear
leukocytes, and soluble factors (e.g., complement).
Dif: cognitive level: i
4. An undesirable consequence of immunity is
a. Natural resistance.
b. Acquired resistance to infectious diseases.
, c. An autoimmune disorder.
d. Recovery from infectious disease.
ANS; c
The desirable consequences of immunity include natural resistance, recovery, and acquired
resistance to infectious diseases. A deficiency or dysfunction of the immune system can cause
many disorders. Undesirable consequences of immunity include allergy, rejection of a
transplanted organ, or an autoimmune disorder.
Dif: cognitive level: i
5. The immune system has various distinctive characteristics except;
a. Specificity.
b. Memory.
c. Mobility.
d. Noncooperation among different cells.
ANS; d
The immune system is composed of a large, complex set of widely distributed elements, with
the distinctive characteristics of specificity, memory, mobility, replicability, and cooperation
among different cells or cellular products. Specificity and memory are characteristics of
lymphocytes in the immune system. Nonspecific elements of the immune system demonstrate
mobility. In addition, specific and nonspecific cellular components of the immune system can
replicate. Cooperation is required for optimal functioning, and interaction involves specific
cellular elements, cell products, and nonlymphoid elements.
Dif: cognitive level: i
6. Hematopoiesis occurs in the yolk sac during the
a. Immediate hours after conception
b. Second month of gestation.
c. Second trimester of gestation.
d. Periods of severe anemia in children.
ANS; a
The sites of blood cell development, or hematopoiesis, follow a definite sequence in the
embryo and fetus. Hematopoiesis occurs in the yolk sac during the second month of gestation.
Dif: cognitive level: ii
7. The sequence of blood cell development in the embryo and fetus is
a. Yolk sac, liver-spleen, bone marrow.
b. Yolk sac, bone marrow, liver/spleen.
c. Liver-spleen, yolk sac, bone marrow.
d. Bone marrow, liver-spleen, yolk sac.
ANS; a
