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HESI A2 (Anatomy & Physiology) V1/V2 & Biology 2025

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HESI A2 (Anatomy & Physiology) V1/V2 & Biology 2025 study resource with practice questions, answers, and rationales. Covers cells, genetics, enzymes, macromolecules, tissues, organ systems, ecology, evolution, and physiology concepts. Designed to strengthen biology knowledge and support exam readiness.

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HESI A2 (Anatomy & Physiology)
V1/V2 & Biology
1. What is a characteristic of viral herpes
 Skin Eruption

2. When a boxer gets hit & has a deviated septum?
 Vomer (in nose)

3. Which of the following is a structure found in the upper respiratory?
 Pharynx

4. A person who has damage to their ulnar nerve will have decreased
sensation in?
 Arm, inability to abduct arms and fingers

5. Which bone does not articulate with any other bone?
 Hyoid Bone

6. Which of the following statements best describes endocrine glands?
 They secrete chemicals into the blood, growth, metabolism, sexual
development and function

7. Diet is important because bone are storage places for?
 Calcium & Phosphorus

8. Which organ is part of both the male reproductive system and urinary
system?
 Urethra

9. Ligaments provide which connection?
 Bone to bone

10. Which structure conducts urine from the kidney to the urinary bladder?
 Ureter

11. Anaerobic respiration can lead to a burning sensation cause by which
molecule?
 Lactic Acid
12. As a part of the negative feedback system, which type of cell is
stimulated to re-absorb bone matrix in response to a decrease in
calcium in the blood?

, Osteoclasts (break down bone so it can release Ca+ into interstitial
fluid)

13. Sweat on the skin's surface cools the body through which process?
 Evaporation

14. When assessing a female client who describes herself as a vegetarian
and the nurse notes that she has a unusual skin color. The nurse
should ask the client if she has eaten a large amount of?
 Carrot and squash

15. Which hand position describes an anatomical position of a person
who is standing erect with feet forward?
 Palms facing anterior

16. Which structure is a ball & socket joint?
 Shoulder

17. Which anatomical structure houses the malleus, incus & stapes?
 Skull & Ear

18. What are like cells grouped together called?
 Tissue

19. The pulse point located behind the knee is palpated over which artery?
 Popliteal

20. Ceruminous (aprocrine) glands secrete?
 Earwax

21. What type of synovial joint is the elbow?
 Hinge

22. What occurs when the sympathetic nervous system is stimulated /
increased?
 Cardiac output



23. Where does digestion begin in the digestive system
 Oral cavity

,24. Which cell structure regulates the transport of substances in & out of
a cell?
 Plasma Membrane

25. The mediastinum is located within which cavity?
 Thoracic cavity

26. What is the effect of Serotonin, a neurotransmitter?
 Involved with mood, anxiety, sleep, happiness, appetite

27. What is the response of cells in the collecting tubules in nephrons
when antidiuretic hormone (ADH) is secreted?
 H2O is re-absorbed from urinary filtrate

28. What is the function of thrombocytes (platelets)?
 Blood clotting

29. Which muscle of the quad femoris group lies on the outer side surface
of lower extremity?
 Vastus Lateralis

30. Which structure is located on the sternum
 Xiphoid Process

31. The occipital region is located in which part of the body?
 Head / Skull

32. Which structure carries oxygen to the cells?
 Hemoglobin

33. Which gland is commonly known as the "Master Gland?"
 Pituitary Gland

34. Aspirin occurs when there is a tear in which structures?
 Ligament

35. What epidermal derivative is involved in temperature homeostasis?
 Eccrine gland (Merocrine / Sweat gland)


36. Which statement are true about bone?
 Osteoblasts (build up of bone), Epiphysial (end of bone), Diaphysis
(shaft of bone)

, 37. Aqueous humor is watery fluid in which part of the body?
 Eye (in front of eye, between the lens & cornea)

38. The malleus, incus & stapes are located in which part of the body?
 Ear

39. Dorsiflexion & Plantarflexion are types of joint movement that are
associated with which part of the body
 Foot

40. Within which vessel does blood return from the lungs?
 Pulmonary vein (Remember pulmonary is heart, veins take
deoxygenated blood back to the heart, Arteries carry oxygen &
nutrients away from the heart)

41. Which part of the brain is involved in auditory functioning
 Temporal Lobe

42. What internal structure of the ear is concerned with hearing?
 Cochlea

43. Fertilization of an ovum occurs in which anatomical structure?
 Fallopian tubes (also called uterine tubes)

44. Where is the tibialis anterior muscle located?
 Lower leg

45. An over production of cerumen (earwax) can accumulate in which
area?
 External ear and canals

46. The mitral valve is located between which two structures?
 Left ventricle and left atrium

47. The olfactory nerve is associated in which sense?
 Smell



48. Vessel carries blood from the body to the heart?
 Vena cava

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