ASCP MB Exam 2026 Questions and Answers

ASCP MB Exam 2026 Questions and
Answers

Acute Promylocity Leukemia (APL) - Correct Answer -t(15:17)

PML / RARa genes

Chronic Myelogenous Leukemia (CML) - Correct Answer -t(9:22)

a.k.a. Philadelphia chromosome

ABL1 / BCR genes

Burkitt's non-Hodkin's Lymphoma - Correct Answer -t(8:14)

dysregulation of c-myc gene

breakpoints on ch.8 spread over 190kbp region 5' to 3'

Follicular non-Hodkin's Lymphoma - Correct Answer -t(14:18)

IgH / BCL2 genes

Mantle Cell Lymphoma (MCL) - Correct Answer -t(11:14)

CCND1 / IgH genes


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, overexpression of cyclin D1 (cell cycle gene)

MALT Lymphoma

(a.k.a. Marginal Zone) - Correct Answer -t(11:18)

API2 / MLT genes

"mucosa-associated lymphoid tissue"

Haploid Genome - Correct Answer -3.3 billion bp

Carbamazepine Resistance - Correct Answer -HLA B1502

Factor V Leiden - Correct Answer -c.1691G>A / p.R506Q

causes Thrombophilia

Cystic Fibrosis mutation - Correct Answer -delta F508, 3bp deletion

HERceptin Therapy - Correct Answer -HER2+/neu

Overexpression of HER2 receptors causing cancer cells to grow

Vancomycin Resistance (Enterococcus) - Correct Answer -van A

MRSA (resistant staph) - Correct Answer -mec A

Mycobacterium tuberculosis - Correct Answer -katG, inhA

Most cancerous HPV - Correct Answer -Strain 16 - 70% of all cases


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