Psychopharmacology 552 Exam 3 Questions and Answers Fully Solved Latest Update 2025-
2026
Naloxone (Narcan) - Answers opiate antagonist, reverses opioid induced respiratory depression
Treatment of choice for all patients with opioid use disorder
Very short half-life
What is Methadone also known as? - Answers Dolophine
What type of opioid receptor agonist is Methadone? - Answers Long-acting full agonist at the
mu receptor
How often is Methadone dosed? - Answers Once daily
In what type of programs is Methadone use restricted? - Answers Federally licensed substance
abuse treatment programs
What should be monitored when using Methadone? - Answers QTC prolongation
What is Buprenorphine (Buprenex, Sublocade)? - Answers Partial Opioid receptor agonist
What is the function of Buprenorphine/Naloxone (Suboxone)? - Answers Opioid antagonist
What effect does Buprenorphine have on cravings? - Answers Decreases cravings
What precaution is needed when using Suboxone in outpatient settings? - Answers Waiver
needed to prescribe in outpatient settings
What can happen if Buprenorphine is used too soon after a full opioid agonist? - Answers Can
precipitate withdrawal
How does Suboxone interact with residual opioids from mu receptors? - Answers It will displace
any residual opioids from the mu receptors
What is the route of administration for Suboxone? - Answers Sublingual preparation
In what situation can Suboxone be used in managing pain? - Answers Opioid Use disorder w/
comorbid pain
What type of antagonist is Naltrexone? - Answers Competitive opioid antagonist
What can happen if Naltrexone is used within 7 days of heroin use? - Answers Precipitate
withdrawal
How is Naltrexone available for use? - Answers Orally or monthly depot injection
When is Naltrexone considered the treatment of choice? - Answers For highly motivated
, patients
What is a potential risk associated with Naltrexone use? - Answers Risk for LFT elevation
Naltrexone - Answers Available PO (Revia) Available IM (Vivitrol)
Buprenorphine (Buprenex, Sublocade) Buprenorphine/Naloxone (Suboxone) - Answers
Suboxone= available Buccal film, sublingual film, sublingual tab Buprenorphine= Available
sublingual tab; subdermal implant, SQ injection
What are the common symptoms of opioid overdose? - Answers Miosis, Hypotension,
Bradycardia, Low RR, Unconsciousness
How is opioid overdose managed? - Answers Naloxone
What are the symptoms of opioid withdrawal? - Answers Anxiety, Lacrimation, Muscle aches,
Abdominal cramps, Diarrhea, Seizures
What medications are used for opioid withdrawal management? - Answers
Buprenorphine/naloxone, Clonidine, Bentyl
In opioid detoxification, which medication is more effective at suppressing withdrawal
symptoms towards the end of the taper? - Answers Buprenorphine (compared to methadone)
What are some symptoms of cocaine use? - Answers Auditory hallucinations, agitation, violent
behavior, muscle twitching, hypertension, tachycardia
How is lorazepam used in the treatment of cocaine use disorder? - Answers It is used to treat
agitation and muscle twitching associated with cocaine use
How does Antabuse work in the treatment of cocaine use disorder? - Answers It increases
synaptic dopamine in the brain reward circuit and acts as an agonist treatment
What medications are used for cocaine-induced chest pain and myocardial infarction? -
Answers Nitroglycerin and Aspirin
Why is Metoprolol contraindicated in patients with cocaine-induced chest pain? - Answers It
further lowers coronary blood flow, worsening ischemia
alcohol use disorder - Answers alcohol use marked by tolerance, withdrawal, and a drive to
continue problematic use
What are the symptoms of mild Alcohol Use Disorder? - Answers Insomnia, Irritability, Hand
tremor
What are the symptoms of moderate Alcohol Use Disorder? - Answers Autonomic hyperactivity
(diaphoresis, tachycardia, hypertension), Fever
2026
Naloxone (Narcan) - Answers opiate antagonist, reverses opioid induced respiratory depression
Treatment of choice for all patients with opioid use disorder
Very short half-life
What is Methadone also known as? - Answers Dolophine
What type of opioid receptor agonist is Methadone? - Answers Long-acting full agonist at the
mu receptor
How often is Methadone dosed? - Answers Once daily
In what type of programs is Methadone use restricted? - Answers Federally licensed substance
abuse treatment programs
What should be monitored when using Methadone? - Answers QTC prolongation
What is Buprenorphine (Buprenex, Sublocade)? - Answers Partial Opioid receptor agonist
What is the function of Buprenorphine/Naloxone (Suboxone)? - Answers Opioid antagonist
What effect does Buprenorphine have on cravings? - Answers Decreases cravings
What precaution is needed when using Suboxone in outpatient settings? - Answers Waiver
needed to prescribe in outpatient settings
What can happen if Buprenorphine is used too soon after a full opioid agonist? - Answers Can
precipitate withdrawal
How does Suboxone interact with residual opioids from mu receptors? - Answers It will displace
any residual opioids from the mu receptors
What is the route of administration for Suboxone? - Answers Sublingual preparation
In what situation can Suboxone be used in managing pain? - Answers Opioid Use disorder w/
comorbid pain
What type of antagonist is Naltrexone? - Answers Competitive opioid antagonist
What can happen if Naltrexone is used within 7 days of heroin use? - Answers Precipitate
withdrawal
How is Naltrexone available for use? - Answers Orally or monthly depot injection
When is Naltrexone considered the treatment of choice? - Answers For highly motivated
, patients
What is a potential risk associated with Naltrexone use? - Answers Risk for LFT elevation
Naltrexone - Answers Available PO (Revia) Available IM (Vivitrol)
Buprenorphine (Buprenex, Sublocade) Buprenorphine/Naloxone (Suboxone) - Answers
Suboxone= available Buccal film, sublingual film, sublingual tab Buprenorphine= Available
sublingual tab; subdermal implant, SQ injection
What are the common symptoms of opioid overdose? - Answers Miosis, Hypotension,
Bradycardia, Low RR, Unconsciousness
How is opioid overdose managed? - Answers Naloxone
What are the symptoms of opioid withdrawal? - Answers Anxiety, Lacrimation, Muscle aches,
Abdominal cramps, Diarrhea, Seizures
What medications are used for opioid withdrawal management? - Answers
Buprenorphine/naloxone, Clonidine, Bentyl
In opioid detoxification, which medication is more effective at suppressing withdrawal
symptoms towards the end of the taper? - Answers Buprenorphine (compared to methadone)
What are some symptoms of cocaine use? - Answers Auditory hallucinations, agitation, violent
behavior, muscle twitching, hypertension, tachycardia
How is lorazepam used in the treatment of cocaine use disorder? - Answers It is used to treat
agitation and muscle twitching associated with cocaine use
How does Antabuse work in the treatment of cocaine use disorder? - Answers It increases
synaptic dopamine in the brain reward circuit and acts as an agonist treatment
What medications are used for cocaine-induced chest pain and myocardial infarction? -
Answers Nitroglycerin and Aspirin
Why is Metoprolol contraindicated in patients with cocaine-induced chest pain? - Answers It
further lowers coronary blood flow, worsening ischemia
alcohol use disorder - Answers alcohol use marked by tolerance, withdrawal, and a drive to
continue problematic use
What are the symptoms of mild Alcohol Use Disorder? - Answers Insomnia, Irritability, Hand
tremor
What are the symptoms of moderate Alcohol Use Disorder? - Answers Autonomic hyperactivity
(diaphoresis, tachycardia, hypertension), Fever
