Rasmussen College MDC 4 Exam 2
Verified Questions and Answers with
Detailed Rationales |
100% Verified Answers (50 Qs - 6 or 7
SATA; 3 or 4 Dose Calc;-Trinity)
A 35-year-old woman receives her seasonal influenza vaccine. Two weeks later, her laboratory
tests reveal a significant increase in a specific antibody that provides long-term protection and
can cross the placenta to confer fetal immunity.
Question:
Which immunoglobulin is most likely elevated in her serum?
- IgA
- IgM
- IgG
- IgE
C) IgG
Rationale:
IgG is the most abundant immunoglobulin in the serum and plays a critical role in long-term
immunity. It is also the only immunoglobulin that crosses the placenta, providing passive
immune protection to the fetus. During the secondary immune response (such as after
vaccination), IgG levels rise significantly, making it the correct choice in this scenario
A nurse is caring for a patient with recurrent upper respiratory and gastrointestinal infections.
The nurse wants to understand which immunoglobulin is pivotal in protecting the mucosal
surfaces from pathogen exposure.
Question:
Which immunoglobulin is predominantly found in secretions (such as saliva, tears, and
mucus) to provide localized immunity?
- IgG
- IgA
- IgM
- IgD
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B) IgA
Rationale:
IgA is the major immunoglobulin involved in mucosal immunity. It is secreted in areas such as
the respiratory, gastrointestinal, and urogenital tracts, where it binds to pathogens and
prevents their attachment to mucosal surfaces. This localized protection helps reduce the
incidence of infections in these regions.
A 28-year-old patient presents with a sudden onset of fever, chills, and malaise following a
suspected exposure to a bacterial pathogen. Laboratory tests reveal markedly elevated
immunoglobulin levels.
Question:
Which immunoglobulin is most indicative of an early primary immune response in this
patient?
- IgG
- IgA
- IgM
- IgE
C) IgM
Rationale:
IgM is the first antibody produced by the immune system when a new antigen is encountered.
Its pentameric structure makes it highly effective in neutralizing pathogens during the initial
phase of an infection. Therefore, elevated IgM levels indicate an early-stage (primary)
immune response.
A nurse assesses a patient who has been exposed to a known allergen and is now
experiencing symptoms such as wheezing, hives, and difficulty breathing.
Question:
Which immunoglobulin is primarily responsible for mediating this type I hypersensitivity
(allergic) reaction?
- IgA
- IgM
- IgG
- IgE
D) IgE
Rationale:
IgE is the immunoglobulin most closely associated with allergic reactions. It binds to allergens
and subsequently triggers the degranulation of mast cells and basophils, leading to the
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release of histamine and other inflammatory mediators. This cascade of events causes the
classic signs of allergic reactions.
In a routine laboratory evaluation, a technician notes that immature B cells display surface
immunoglobulins that participate in antigen recognition and signal B-cell activation.
Question:
Which immunoglobulin is primarily expressed on the surface of these B cells?
- IgA
- IgG
- IgD
- IgE
C) IgD
Rationale:
IgD is predominantly found on the surface of immature (naïve) B cells. It plays a role in the
activation and regulation of the B cell response. Although its complete function is less
understood than other immunoglobulins, its presence is essential for initiating immune
responses as B cells mature.
Raynaud's phenomenon is best defined as:
o A) An autoimmune disorder primarily affecting the joints
o B) An episodic vasospastic disorder of small cutaneous arteries
o C) A chronic inflammatory skin disorder
o D) A disease of large arteries causing claudication
B) An episodic vasospastic disorder of small cutaneous arteries
Rationale: Raynaud's phenomenon is characterized by episodic vasospasm of small
arteries, typically in the fingers and toes
Common triggers for Raynaud's phenomenon include:
o A) Exposure to high temperatures
o B) Emotional stress
o C) High cholesterol levels
o D) Hypoglycemia
B) Emotional stress
Rationale: Emotional stress, along with exposure to cold, can trigger episodes of
Raynaud's phenomenon.
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When educating a client about managing Raynaud's phenomenon, which statement
by the nurse is most appropriate?
o A) "Use ice packs during an episode to relieve symptoms."
o B) "Avoid exposure to cold and manage stress to reduce episodes."
o C) "Drink plenty of cold fluids to avoid dehydration."
o D) "Taking aspirin daily will prevent episodes."
B) "Avoid exposure to cold and manage stress to reduce episodes."
Rationale: Avoiding cold and managing stress are key in reducing the frequency and
severity of Raynaud's attacks
Which medication may be prescribed to manage Raynaud's phenomenon by
improving blood flow?
o A) Calcium channel blockers
o B) Beta blockers
o C) Diuretics
o D) ACE inhibitors
A) Calcium channel blockers
Rationale: Calcium channel blockers, such as nifedipine, are commonly used to improve
blood flow and reduce the frequency and severity of Raynaud's attack
A key aspect of client education for systemic lupus erythematosus (SLE) includes:
o A) Discontinuing medication when symptoms improve
o B) Limiting exposure to sunlight to reduce flares
o C) Engaging in strenuous exercise to reduce joint pain
o D) Maintaining a high-protein diet
B) Limiting exposure to sunlight to reduce flares
Rationale: Sunlight can trigger flares in SLE, so clients are advised to limit exposure
Which manifestation is commonly seen in clients with systemic lupus
erythematosus?
o A) Erythematous butterfly rash on the face
o B) Persistent dry cough
o C) Joint deformities similar to RA
o D) Hyperglycemia
A) Erythematous butterfly rash on the face
Rationale: A butterfly-shaped rash on the face is a classic manifestation of SLE.
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