QUESTIONS AND ANSWERS
Potency is related to - ANS dose. Potency is greater when a dose is smaller
efficacy is - ANS the maximum response of a drug regardless of dose
What is first past effect? - ANS When orally administered drugs pass through the hepatic
portal which reduces the amount effective drug. this requires large doses of a drug
What drug administration route is used to deliver protein products? - ANS Subcutaneous
The TB skin test is an example of what route of drug administration? - ANS Intradermal
The study of how we drug enters the body, circulates in the body and leaves the body -
ANS pharmacokinetics
What organ is involved in absorption of oral drugs? - ANS small intestine
What is the most important site for metabolism of drugs? - ANS the liver
What is the most important organ that is involved in excretion? - ANS kidneys
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, What terminates drug effects? - ANS elimination
What steps do intra-vascular drugs bypass? - ANS absorption and first pass
What drugs are known to move across biological membranes by diffusion? - ANS Lipid
soluble drugs
Metabolism is also known as - ANS Bio transformation
Side effects are - ANS Dose related reaction that is not part of the desired therapeutic action
True or false: an allergic reaction is related to dose - ANS false
An abnormal drug response that is usually genetically determined - ANS Idiosyncrasy
What are the two branches of the autonomic nervous system? - ANS Sympathetic and
parasympathetic
What are some effects of the sympathetic nervous system? - ANS Fight or flight
Increase blood pressure through vasoconstriction
Dilate pupils and bronchioles
Reduce salivary flow
The preganglionic neurotransmitter for the sympathetic nervous system is -
ANS Acetylcholine
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The Post ganglionic neurotransmitter for the sympathetic nervous system is -
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ANS Norepinephrine
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, What drugs mimic the sympathetic nervous system? - ANS Adrenergic drugs
What diseases should avoid adrenergic drugs? - ANS angina, uncontrolled hypertension and
uncontrolled hyperthyroidism
What is dopamine used to treat? And what class of drugs is it? - ANS Shock, Low blood
pressure, parkinson's. adrenergic
Andrenergic blocking drugs are used to treat - ANS High blood pressure, angina, glaucoma
and myocardial infarction
Propanolol is also known as:
And it is a - ANS Inderal
Nonselective beta blocker to treat hypertension
Atenolol is also known as:
And it is a - ANS Tenormin
Selective beta blocker to treat hypertension
Lopressor is also known as
And it is a - ANS Metoprolol
selective beta blocker to treat hypertension
pilocarpine is an example of a:
what two diseases can it treat? - ANS cholinergic drug.
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It increases saliva flow in patients with sjogrens
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