Clinical Neuroscience Final Exam 2 Questions With
Complete Solutions
4 Laws of Behavioral Genetics Correct Answers 1.) all human
behavioral traits are heritable
2.) the effects of being raised in the same family is smaller than
the effects of genes
3.) a substantial portion of the variations between human
behavioral traits is not accounted for by the effects of genes or
family
4.) a typical behavioral trait is associated with many genetic
variants, each of which accounts for a small percentage of that
behavioral trait
Angelman and Prader-Willi (genetic disorder) Correct Answers
○caused by the deletion of same gene
Angleman:
○maternal origin
Prader-Willi
○paternal origin
Associativity (regarding LTP) Correct Answers transmission
at one synapse can increase the strength of transmission at
another synapse that is activate at the same time
Ca2+ Signal Cascade Correct Answers Binds to Calmodulin:
○activates PKA and PKC which activates CREB synthesis
Binds to Calbindin:
○inhibits Ca2+ effects
Stores Ca2+ in ER and Mitochondria:
○restores original [Ca2+]
, Calculating Heritability Correct Answers ○a^2: additive
genetic effects
○c^2: shared environment effects
○e^2: unshared environment effects
CAMP Cascade Correct Answers activates protein kinase A
(PKA) which increases protein phosphorylation
Capgras Syndrome Correct Answers ○amygdala dysfunction
(part associated with emotional recognition)
○delusion people are replaced by others
Causes of Brain Damage Correct Answers ○brain tumors
○cerebrovascular disorders (strokes)
○closed-head injuries
○neurotoxins
○genetics
Central Pattern Generators Correct Answers ○interneuron
circuits that control order and timing of movements
○controlled by descending input and afferent input
Cognitive Endophenotypes of Depression Correct Answers
○impairment of attention
○depressive dementia
○negative cognitive bias
DAG Signal Cascade Correct Answers activates protein kinase
C (PKC) which increases protein phosphorylation and activates
Ca2+-binding proteins
Complete Solutions
4 Laws of Behavioral Genetics Correct Answers 1.) all human
behavioral traits are heritable
2.) the effects of being raised in the same family is smaller than
the effects of genes
3.) a substantial portion of the variations between human
behavioral traits is not accounted for by the effects of genes or
family
4.) a typical behavioral trait is associated with many genetic
variants, each of which accounts for a small percentage of that
behavioral trait
Angelman and Prader-Willi (genetic disorder) Correct Answers
○caused by the deletion of same gene
Angleman:
○maternal origin
Prader-Willi
○paternal origin
Associativity (regarding LTP) Correct Answers transmission
at one synapse can increase the strength of transmission at
another synapse that is activate at the same time
Ca2+ Signal Cascade Correct Answers Binds to Calmodulin:
○activates PKA and PKC which activates CREB synthesis
Binds to Calbindin:
○inhibits Ca2+ effects
Stores Ca2+ in ER and Mitochondria:
○restores original [Ca2+]
, Calculating Heritability Correct Answers ○a^2: additive
genetic effects
○c^2: shared environment effects
○e^2: unshared environment effects
CAMP Cascade Correct Answers activates protein kinase A
(PKA) which increases protein phosphorylation
Capgras Syndrome Correct Answers ○amygdala dysfunction
(part associated with emotional recognition)
○delusion people are replaced by others
Causes of Brain Damage Correct Answers ○brain tumors
○cerebrovascular disorders (strokes)
○closed-head injuries
○neurotoxins
○genetics
Central Pattern Generators Correct Answers ○interneuron
circuits that control order and timing of movements
○controlled by descending input and afferent input
Cognitive Endophenotypes of Depression Correct Answers
○impairment of attention
○depressive dementia
○negative cognitive bias
DAG Signal Cascade Correct Answers activates protein kinase
C (PKC) which increases protein phosphorylation and activates
Ca2+-binding proteins
