, SSRI - CORRECT ANSWERS -Common side effects = headache, GI upset, sleep
disturbance, sexual dysfunction (aorgasmia), agitation, SIADH (esp. in elderly),
discontinuation syndrome, serotonin syndrome (when combined with MAO-I)
Indications: depressive/anxiety symptoms (higher dose for OCD)
Paroxetine (PAXEL) - CORRECT ANSWERS -SSRI
Short T1/2 --> increased risk of discontinuation syndrome and withdrawal
Teratogenic --> contraindicated in pregnancy
Fluoxetine (PROZAC) - CORRECT ANSWERS -SSRI
Long T1/2 --> longer washout period (5 weeks)
Indication: non-compliant patients
Sertraline (ZOLOFT) - CORRECT ANSWERS -SSRI
Indication: patients with cardiac dysfunction (s/p MI, CHF)
Escitalopram (LEXAPRO) - CORRECT ANSWERS -SSRI
Very few side effects
Very few drug-drug interactions
Stronger than Citalopram
Indication: patients with multiple diseases taking multiple medications
Citalopram - CORRECT ANSWERS -SSRI
Very few side effects
Very few drug-drug interactions
Weaker than Escitalopram
Indication: patients with multiple diseases taking multiple medications
Fluvoxamine (LUVOX) - CORRECT ANSWERS -Indication: OCD
Venlefaxine (EFFEXOR) - CORRECT ANSWERS -SNRI
Side effects: HTN --> monitor BP
Short T1/2 --> increased risk of withdrawal
Indication: Anxiety and Depression
Duloxetine (CYMBALTA) - CORRECT ANSWERS -SNRI
Indication: patients with pain symptoms (i.e. Neuropathic pain, Fibromyalgia)
Mirtazepine (REMERON) - CORRECT ANSWERS -Tetracyclic Antidepressant (blocks
the alpha-2 receptor to increase NE and 5-HT transmission)
disturbance, sexual dysfunction (aorgasmia), agitation, SIADH (esp. in elderly),
discontinuation syndrome, serotonin syndrome (when combined with MAO-I)
Indications: depressive/anxiety symptoms (higher dose for OCD)
Paroxetine (PAXEL) - CORRECT ANSWERS -SSRI
Short T1/2 --> increased risk of discontinuation syndrome and withdrawal
Teratogenic --> contraindicated in pregnancy
Fluoxetine (PROZAC) - CORRECT ANSWERS -SSRI
Long T1/2 --> longer washout period (5 weeks)
Indication: non-compliant patients
Sertraline (ZOLOFT) - CORRECT ANSWERS -SSRI
Indication: patients with cardiac dysfunction (s/p MI, CHF)
Escitalopram (LEXAPRO) - CORRECT ANSWERS -SSRI
Very few side effects
Very few drug-drug interactions
Stronger than Citalopram
Indication: patients with multiple diseases taking multiple medications
Citalopram - CORRECT ANSWERS -SSRI
Very few side effects
Very few drug-drug interactions
Weaker than Escitalopram
Indication: patients with multiple diseases taking multiple medications
Fluvoxamine (LUVOX) - CORRECT ANSWERS -Indication: OCD
Venlefaxine (EFFEXOR) - CORRECT ANSWERS -SNRI
Side effects: HTN --> monitor BP
Short T1/2 --> increased risk of withdrawal
Indication: Anxiety and Depression
Duloxetine (CYMBALTA) - CORRECT ANSWERS -SNRI
Indication: patients with pain symptoms (i.e. Neuropathic pain, Fibromyalgia)
Mirtazepine (REMERON) - CORRECT ANSWERS -Tetracyclic Antidepressant (blocks
the alpha-2 receptor to increase NE and 5-HT transmission)
