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1. Bipolar I disorder - ANSWER ✔ Characterized by one or more
episodes of mania and one or more depression episodes. It is the
most severe type of bipolar disorder and is typically treated with
antipsychotics.
2. Bipolar disorder - ANSWER ✔ Mood disorders with recurrent
episodes of depression and mania. Mania is characterized by
abnormally elevated mood, rapid thoughts, actions, speech, and
spending sprees. Risk factors include genetics, psychological
stress, substance use disorder, and relapse.
3. Mood-stabilizing medications - ANSWER ✔ Include lithium,
antiepileptic medications (valproic acid, carbamazepine), and
antipsychotics. Antidepressants should not be used to treat bipolar
, disorder, and if used, should be prescribed with a mood stabilizer
to prevent rebound mania.
4. Normal lithium range - ANSWER ✔ Therapeutic range is 0.8 - 1.2
mEq/L. Below range may lead to diarrhea, nausea, vomiting, and
muscle weakness, while above range may cause polydipsia, urinary
incontinence, mental confusion, and ECG changes.
5. Interventions for manic patients - ANSWER ✔ Involve decreased
stimulation and promotion of relaxation, focusing on safety and
maintaining physical health, and using therapeutic milieu to
provide a safe environment during an acute phase.
6. Bipolar II disorder - ANSWER ✔ Characterized by one or more
episodes of hypomania and one or more depression episodes. It is
less severe than bipolar I disorder.
7. Antiepileptic medications - ANSWER ✔ Include valproate and
carbamazepine (Tegretol), used to treat bipolar disorder. Valproate
may lead to hepatotoxicity, pancreatitis, thrombocytopenia,
teratogenesis, and weight gain. Carbamazepine may cause blood
dyscrasias, teratogenesis, hyperosmolarity, skin disorders, and
CNS side effects.