Pharm Chapter 21 musculoskeletal and anti-inflammatory drugs (repost).

Pharm Chapter 21 musculoskeletal and anti-
inflammatory drugs (repost).
Skeletal Muscle Relaxants (uses)

For treatment of acute musculoskeletal conditions associated with pain, spasm, contraction, or
impaired motility on a short-term basis.

Diazepam/Valium)

Skeletal muscle relaxant for acute, painful musculoskeletal conditions

Methocarbamol/Robaxin

Skeletal muscle relaxant for acute, painful musculoskeletal conditions

Baclofen/Lioresal

Skeletal muscle relaxant for spasticity with spinal cord injury/disease

Carisoprodol/Soma

Skeletal muscle relaxant. Caution w/ asthma and abuse.

Cyclobenzaprine/Flexeril

Skeletal muscle relaxant w/ strong anticholinergic side effects

Dantrolene/Dantrium

Skeletal muscle relaxant for multiple sclerosis and cerebral palsy.
Not for trauma, ALS, or rheumatic disorders.

Tiazanidine/Zanaflex

Skeletal muscle relaxant for increased muscle tone associated with spasticity.

Skeletal Muscle Relaxants (side effects)

Drowsiness/Dizziness
Dry mouth/GI symptoms
Weakness/tremor/ataxia
Confusion/Nervousness
Blurred vision
Hypotension

, Hypersensitivity
Respiratory depression

Skeletal Muscle Relaxants (contraindications)

Hypersensitivity
Pregnancy/Lactation

Skeletal Muscle Relaxants (caution)

Drug abuse
Renal/Hepatic dysfunction
Blood/cardiac disorders
Older adults
Abrupt discontinuation
Closed-angle glaucoma

Skeletal Muscle Relaxants (potentation interactions)

Alcohol
Analgesics
Psychotropics
Antihistamines

Skeletal Muscle Relaxants (patient education)

Side effects
Care with driving
Avoidance of other CNS depressants
Care with analgesics
RICE (rest, ice, compression, elevation)
Only as long as necessary/avoid prolonged use
Dependence/withdrawal

Anti-inflammatory Drugs

Treat arthritis, bursitis, spondylitis, gout, muscle strains and sprains. GI and blood related side
effects common. NSAIDs and gout meds.

NSAIDs

Treat rheumatic conditions, sprains, cramps.

NSAIDs (side effects)