TEST BANK$ri
Modern Blood Banking & Transfusion Practices
$ri $ri $ri $ri $ri
by Denise M. Harmening
$ri $ri $ri
Sixth Edition
$ri
,Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
$ri $ri $ri $ri $ri $ri $ri $ri $ri $ri
Multiple $riChoice
Identify $rithe $richoice $rithat $ribest $ricompletes $rithe $ristatement $rior $rianswers $rithe $riquestion.
1. Which $rimetabolic $ripathway $riis $riresponsible $rifor $rigenerating $ri90% $riof $rithe $riATP$rifor $rithe $riRBC?
a. Pentose $riphosphate $rishunt c. Glycolysis
b. Luebering-Rapoport $ r i shunt d. $ r i $ r i Methemoglobin $rireductase
2. A $riunit $riof $riblood $riwas $rireturned $rito $rithe $riblood $ribank $ribefore $riit $riwas $rispiked. $riApparently $rithe $ripatient’s
$riIV $rifailed. $riThe $riunit $riof $riblood $riwas $rioutside $rithe $riblood $ribank $rifor $ri35 $riminutes. $riWhich $riof $rithe
$ristatements $ribelow $riis $rimost $riaccurate?
a. The $riunit $riof $riblood $rishould $ribe $ridiscarded $riimmediately.
b. The $riunit $riof $riblood $rican $ribe $rireturned $rito $riinventory.
c. The $riunit $riof $riblood $rimust $ribe $ritransfused $riwithin $ri4 $rihours $rior $ribe $ridiscarded $riat $rithe $riend $riof $rithat $ritime.
d. The $riunit $riof $riblood $rimust $ribe $ritransfused $riwith $ri24 $rihours.
3. What $riis $rithe $riaverage $ridiameter $riof $ria $riplatelet?
a. 5 $rito $ri10 $riµm c. 1 $rito $ri2 $riµm
b. 2 $rito $ri4 $riµm d. $ r i $ r i 4 $rito $ri6 $riµm
4. In $rithe $rinormal $rihemoglobin-oxygen $ridissociation $ricurve, $riwhat $ripercentage $riof $rioxygen $riis $rireleased $rito
$rithe $ritissues $riwhen $riPO2 $ r i averages $ri40 $rimm $riHg?
a. 75% c. 100%
b. 25% d. $ r i $ r i 50%
5. What $rifactors $riare $riknown $rito $riinfluence $riplatelet $rimetabolism $riand $rifunction?
a. Storage $ritemperature c. Platelet $ricount
b. Initial $ripH d. $ r i $ r i All $riof $rithe $riabove
6. Which $riof $rithe $rifollowing $rired $riblood $ricell $rimorphologies $rimay $ribe $ripresent $rion $rithe $riperipheral $riblood
$rismear $rias $ria $riresult $riof $riloss $riof $riRBC $rimembrane?
a. Spherocytes c. Burr $ricells
b. Target $ricells d. $ r i $ r i Schistocytes
7. What $ridoes $rithe $riterm $riautologous $ritransfusion $rirefer $rito?
a. A $riparent $ridonating $riblood $rifor $rihis $rior $riher $richild
b. An $riindividual $ridonating $riblood $rifor $ria $rifriend
c. An $riindividual $ridonating $riblood $rifor $ria $rirelative
d. An $riindividual $ridonating $riblood $rifor $rihis $rior $riher $riown $ritransfusion
8. What $riis $rithe $riprimary $rifunction $riof $rihemoglobin?
a. Iron $rimetabolism c. Oxygen $ritransport
b. Porphyrin $risynthesis d. $ r i $ r i Signal $ritransduction
9. All $riof $rithe $rifollowing $riareas $riof $rired $riblood $ricell $ribiology $riare $ricrucial $rifor $rinormal $rierythrocyte $risurvival
$ri except:
a. Cellular $rimetabolism. c. Site $riof $rithe $riABO $riantigen $riattachment.
b. RBC $rimembrane. d. $ r i $ r i Hemoglobin $ristructure.
, $ri 10. $ r i $ r i What $riis $rithe $ricorrect $ribiochemical $ricomposition $riof $rithe $riRBC $rimembrane?
a. 52% $riprotein, $ri40% $rilipid, $ri8% $ricarbohydrate
b. 40% $riprotein, $ri8% $rilipid, $ri52% $ricarbohydrate
c. 8% $riprotein, $ri52% $rilipid, $ri40% $ricarbohydrate
d. 8% $rilipid, $ri40% $ricarbohydrate, $ri52% $riprotein
$ r i 11. $ r i $ r i All $riof $rithe $rifollowing $ribiochemical $richanges $riare $riassociated $riwith $riloss $riof $rired $riblood $ricell $riviability
$ri upon $ristorage
except:
a. Decreased $ripH. c. Increased $riATP $rilevel.
b. Loss $riof $rired $riblood $ricell $rifunction. d. $ r i $ r i Decreased $riglucose $riconsumption.
$ri 12. $ r i $ r i Which $rired $riblood $ricell $ripreservative $rihas $ria $ristorage $ritime $riof $ri35 $ridays?
a. ACD c. AS-1
b. CPDA-1 d. $ r i $ r i CPD
$ri 13. $ r i $ r i The $riRBC $rimembrane $riis $rirelatively $ripermeable $rito $riall $riof $rithe $rifollowing $ r i except:
a. Chloride. c. Bicarbonate.
b. Sodium. d. $ r i $ r i Water.
$ri 14. What $ripercentage $riof $riplatelets $riis $risequestered $riin $rithe $rispleen $rias $rifunctional $rireserve $riafter $ribeing
$ r i
$rireleased $rifrom $rithe $ribone $rimarrow?
a. 30% c. 10%
b. 50% d. $ r i $ r i 25%
$ri 15. $ r i What $riis $rithe $rimajor $ribiochemical $riconsideration $riin $riplatelet $ristorage?
a. Glucose $rimetabolism c. Production $riof $ricarbon $ridioxide
b. Oxygen $risupply d. $ r i $ r i Regulation $riof $ripH
$ri 16. What $riwould $rithe $rihemoglobin-oxygen $ridissociation $ricurve $ridepict $riin $ria $ripatient $riexhibiting
$ r i
clinical $risigns $riof $rialkalosis?
$ri
a. Normal c. Shift $rito $rithe $riright
b. Shift $rito $rithe $rileft d. $ r i $ r i None $riof $rithe $riabove
$ri 17. $ r i $ r i Name $rithe $rimain $rilipid $ricomponents $riof $ria $rired $riblood $ricell $rimembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. $ r i $ r i Glycophorin $riA
$ri 18. $ r i $ r i The $riABO $riblood $rigroups $riwere $ridiscovered $riin $ri1901 $riby $riwhom?
a. Charles $riDrew c. Loutit $riand $riMollison
b. Karl $riLandsteiner d. $ r i $ r i Edward $riLindeman
$ri 19. $ r i A $ristanding $riorder $riof $riplatelets $riwas $rishipped $rito $riyour $rifacility $riby $riyour $risupplier. $riIt $riwas
inadvertently $rileft $riin $rithe $ricorner $riof $rithe $ridepartment $riuntil $ridiscovered $ri36 $rihours $rilater. $riWhat $riwould
$ri
$rithe $riappropriate $riaction $ribe $rifor $rithe $riblood $ribanker?
a. If $rithe $ritemperature $riin $rithe $ribox $riwas $ri22 $ri+/- $ri2°C $riand $rithe $riplatelet $riswirl $riseemed $riOK,
$riit $riwould $ribe $riOK $rito $riaccept $rithe $riunit $riinto $riinventory.
b. The $riplatelets $rihave $rifallen $rioutside $rithe $risupplier’s $riquality $riassurance. $riThe $riunit
$rishould $ribe $ridiscarded $ribecause $rithe $ripH $rihas $riprobably $ridropped $ritoo $rilow $riand
$riplatelet $riactivation $rihas $ribeen $ricompromised.
c. If $rithe $ritemperature $riwas $ri1°C $rito $ri6°C $riand $rithe $riplatelet $riswirl $riseemed $riOK, $riit $riwould $ribe $riOK $rito
, accept $rithe $riunit $riinto $riinventory.
d. If $rithe $riplatelets $riappeared $riOK $riand $ripassed $rithe $riplatelet $riswirl $ritest $riafter $ribeing
$riplaced $rion $rithe $riagitator, $rithey $ricould $ribe $riaccepted $riinto $rithe $riinventory.
$ri 20. $ r i $ r i Which $rimetabolic $ripathway $ripermits $rithe $riaccumulation $riof $ri2,3 $ridiphosphoglycerate $ri(2,3-DPG)?
a. Glycolysis c. Pentose $riphosphate $rishunt
b. Luebering-Rapoport $ r i shunt d. $ r i $ r i Methemoglobin $rireductase
$ r i 21. $ r i $ r i All $riof $rithe $rifollowing $riare $riconsistent $riwith $ria $ri"shift $rito $rithe $riright" $riof $rithe $rihemoglobin-oxygen
dissociation $ricurve
$ri
except:
a. Increased $ri2,3-DPG.
b. 50% $riO2 $ r i saturation $rito $ritissues.
c. Decreased $ri 2,3-DPG.
d. Decreased $rihemoglobin $riaffinity $rifor $riO2.
$ri 22. $ r i $ r i What $riis $rithe $rinormal $riplatelet $ricount $rirange $riper $ricubic $rimillimeter?
a. 100 $rito $ri350 c. 50,000 $rito $ri200,000
b. 150,000 $rito $ri350,000 d. $ r i $ r i 350,000 $rito $ri500,000
$ri 23. $ r i $ r i What $ricryoprotective $riagent $riis $riadded $rito $rired $riblood $ricells $riupon $rifreezing?
a. Dextrose c. Glycerol
b. Adsol d. $ r i $ r i All $riof $rithe $riabove
$ r i 24. $ r i $ r i If $riplatelets $riare $rito $ribe $ristored $rifor $ri5 $ridays $rion $ria $rirotator, $riwhat $riis $rithe $rioptimal $ristorage
$ri temperature?
a. 1°C $rito $ri6°C c. 35°C $rito $ri37°C
b. 20°C $rito $ri24°C d. $ r i $ r i 1°C $rito $ri10°C
$ri 25. $ r i $ r i What $rirole $rido $riplatelets $riplay $riin $rihemostasis?
a. Maintenance $riof $rivascular $riintegrity
b. Initial $riarrest $riof $ribleeding $riby $riplatelet $riplug $riformation
c. Stabilization $riof $rithe $rihemostatic $riplug
d. All $riof $rithe $riabove
$ri 26. $ r i $ r i Which $riof $rithe $rifollowing $ribest $ridescribes $ri"integral" $rimembrane $riproteins?
a. Reside $riat $rithe $ricytoplasmic $risurface $riof $rimembrane
b. Span $rithe $rientire $rimembrane $risurface
c. Form $rithe $rired $riblood $ricell $ricytoskeleton
d. None $riof $rithe $riabove
$ri 27. $ r iHow $riis $ristroma-free $rihemoglobin $risolution $riprepared?
a. Outdated $rired $riblood $ricells $riare $riconcentrated, $riand $ristroma $riis $riremoved.
b. Outdated $rired $riblood $ricells $riare $ridiluted $riwith $risaline, $riand $ristroma $riis $riremoved.
c. Outdated $rired $riblood $ricells $riare $rilysed, $riand $ristroma $riis $riremoved.
d. None $riof $rithe $riabove
$ri 28. $ r i $ r i What $riis $rithe $rinormal $rilife $rispan $riof $rian $riRBC?
a. 100 $ridays c. 120 $rihours
b. 120 $ridays d. $ r i $ r i 2 $ridays
$ri 29. $ r i Regarding $riloss $riof $riRBC $rimembrane $rideformability, $riall $riof $rithe $rifollowing $riare $ritrue $ r i except:
a. Increase $riin$riATP $rilevel.
b. Decrease $riin$riATP $rilevel.
Modern Blood Banking & Transfusion Practices
$ri $ri $ri $ri $ri
by Denise M. Harmening
$ri $ri $ri
Sixth Edition
$ri
,Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
$ri $ri $ri $ri $ri $ri $ri $ri $ri $ri
Multiple $riChoice
Identify $rithe $richoice $rithat $ribest $ricompletes $rithe $ristatement $rior $rianswers $rithe $riquestion.
1. Which $rimetabolic $ripathway $riis $riresponsible $rifor $rigenerating $ri90% $riof $rithe $riATP$rifor $rithe $riRBC?
a. Pentose $riphosphate $rishunt c. Glycolysis
b. Luebering-Rapoport $ r i shunt d. $ r i $ r i Methemoglobin $rireductase
2. A $riunit $riof $riblood $riwas $rireturned $rito $rithe $riblood $ribank $ribefore $riit $riwas $rispiked. $riApparently $rithe $ripatient’s
$riIV $rifailed. $riThe $riunit $riof $riblood $riwas $rioutside $rithe $riblood $ribank $rifor $ri35 $riminutes. $riWhich $riof $rithe
$ristatements $ribelow $riis $rimost $riaccurate?
a. The $riunit $riof $riblood $rishould $ribe $ridiscarded $riimmediately.
b. The $riunit $riof $riblood $rican $ribe $rireturned $rito $riinventory.
c. The $riunit $riof $riblood $rimust $ribe $ritransfused $riwithin $ri4 $rihours $rior $ribe $ridiscarded $riat $rithe $riend $riof $rithat $ritime.
d. The $riunit $riof $riblood $rimust $ribe $ritransfused $riwith $ri24 $rihours.
3. What $riis $rithe $riaverage $ridiameter $riof $ria $riplatelet?
a. 5 $rito $ri10 $riµm c. 1 $rito $ri2 $riµm
b. 2 $rito $ri4 $riµm d. $ r i $ r i 4 $rito $ri6 $riµm
4. In $rithe $rinormal $rihemoglobin-oxygen $ridissociation $ricurve, $riwhat $ripercentage $riof $rioxygen $riis $rireleased $rito
$rithe $ritissues $riwhen $riPO2 $ r i averages $ri40 $rimm $riHg?
a. 75% c. 100%
b. 25% d. $ r i $ r i 50%
5. What $rifactors $riare $riknown $rito $riinfluence $riplatelet $rimetabolism $riand $rifunction?
a. Storage $ritemperature c. Platelet $ricount
b. Initial $ripH d. $ r i $ r i All $riof $rithe $riabove
6. Which $riof $rithe $rifollowing $rired $riblood $ricell $rimorphologies $rimay $ribe $ripresent $rion $rithe $riperipheral $riblood
$rismear $rias $ria $riresult $riof $riloss $riof $riRBC $rimembrane?
a. Spherocytes c. Burr $ricells
b. Target $ricells d. $ r i $ r i Schistocytes
7. What $ridoes $rithe $riterm $riautologous $ritransfusion $rirefer $rito?
a. A $riparent $ridonating $riblood $rifor $rihis $rior $riher $richild
b. An $riindividual $ridonating $riblood $rifor $ria $rifriend
c. An $riindividual $ridonating $riblood $rifor $ria $rirelative
d. An $riindividual $ridonating $riblood $rifor $rihis $rior $riher $riown $ritransfusion
8. What $riis $rithe $riprimary $rifunction $riof $rihemoglobin?
a. Iron $rimetabolism c. Oxygen $ritransport
b. Porphyrin $risynthesis d. $ r i $ r i Signal $ritransduction
9. All $riof $rithe $rifollowing $riareas $riof $rired $riblood $ricell $ribiology $riare $ricrucial $rifor $rinormal $rierythrocyte $risurvival
$ri except:
a. Cellular $rimetabolism. c. Site $riof $rithe $riABO $riantigen $riattachment.
b. RBC $rimembrane. d. $ r i $ r i Hemoglobin $ristructure.
, $ri 10. $ r i $ r i What $riis $rithe $ricorrect $ribiochemical $ricomposition $riof $rithe $riRBC $rimembrane?
a. 52% $riprotein, $ri40% $rilipid, $ri8% $ricarbohydrate
b. 40% $riprotein, $ri8% $rilipid, $ri52% $ricarbohydrate
c. 8% $riprotein, $ri52% $rilipid, $ri40% $ricarbohydrate
d. 8% $rilipid, $ri40% $ricarbohydrate, $ri52% $riprotein
$ r i 11. $ r i $ r i All $riof $rithe $rifollowing $ribiochemical $richanges $riare $riassociated $riwith $riloss $riof $rired $riblood $ricell $riviability
$ri upon $ristorage
except:
a. Decreased $ripH. c. Increased $riATP $rilevel.
b. Loss $riof $rired $riblood $ricell $rifunction. d. $ r i $ r i Decreased $riglucose $riconsumption.
$ri 12. $ r i $ r i Which $rired $riblood $ricell $ripreservative $rihas $ria $ristorage $ritime $riof $ri35 $ridays?
a. ACD c. AS-1
b. CPDA-1 d. $ r i $ r i CPD
$ri 13. $ r i $ r i The $riRBC $rimembrane $riis $rirelatively $ripermeable $rito $riall $riof $rithe $rifollowing $ r i except:
a. Chloride. c. Bicarbonate.
b. Sodium. d. $ r i $ r i Water.
$ri 14. What $ripercentage $riof $riplatelets $riis $risequestered $riin $rithe $rispleen $rias $rifunctional $rireserve $riafter $ribeing
$ r i
$rireleased $rifrom $rithe $ribone $rimarrow?
a. 30% c. 10%
b. 50% d. $ r i $ r i 25%
$ri 15. $ r i What $riis $rithe $rimajor $ribiochemical $riconsideration $riin $riplatelet $ristorage?
a. Glucose $rimetabolism c. Production $riof $ricarbon $ridioxide
b. Oxygen $risupply d. $ r i $ r i Regulation $riof $ripH
$ri 16. What $riwould $rithe $rihemoglobin-oxygen $ridissociation $ricurve $ridepict $riin $ria $ripatient $riexhibiting
$ r i
clinical $risigns $riof $rialkalosis?
$ri
a. Normal c. Shift $rito $rithe $riright
b. Shift $rito $rithe $rileft d. $ r i $ r i None $riof $rithe $riabove
$ri 17. $ r i $ r i Name $rithe $rimain $rilipid $ricomponents $riof $ria $rired $riblood $ricell $rimembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. $ r i $ r i Glycophorin $riA
$ri 18. $ r i $ r i The $riABO $riblood $rigroups $riwere $ridiscovered $riin $ri1901 $riby $riwhom?
a. Charles $riDrew c. Loutit $riand $riMollison
b. Karl $riLandsteiner d. $ r i $ r i Edward $riLindeman
$ri 19. $ r i A $ristanding $riorder $riof $riplatelets $riwas $rishipped $rito $riyour $rifacility $riby $riyour $risupplier. $riIt $riwas
inadvertently $rileft $riin $rithe $ricorner $riof $rithe $ridepartment $riuntil $ridiscovered $ri36 $rihours $rilater. $riWhat $riwould
$ri
$rithe $riappropriate $riaction $ribe $rifor $rithe $riblood $ribanker?
a. If $rithe $ritemperature $riin $rithe $ribox $riwas $ri22 $ri+/- $ri2°C $riand $rithe $riplatelet $riswirl $riseemed $riOK,
$riit $riwould $ribe $riOK $rito $riaccept $rithe $riunit $riinto $riinventory.
b. The $riplatelets $rihave $rifallen $rioutside $rithe $risupplier’s $riquality $riassurance. $riThe $riunit
$rishould $ribe $ridiscarded $ribecause $rithe $ripH $rihas $riprobably $ridropped $ritoo $rilow $riand
$riplatelet $riactivation $rihas $ribeen $ricompromised.
c. If $rithe $ritemperature $riwas $ri1°C $rito $ri6°C $riand $rithe $riplatelet $riswirl $riseemed $riOK, $riit $riwould $ribe $riOK $rito
, accept $rithe $riunit $riinto $riinventory.
d. If $rithe $riplatelets $riappeared $riOK $riand $ripassed $rithe $riplatelet $riswirl $ritest $riafter $ribeing
$riplaced $rion $rithe $riagitator, $rithey $ricould $ribe $riaccepted $riinto $rithe $riinventory.
$ri 20. $ r i $ r i Which $rimetabolic $ripathway $ripermits $rithe $riaccumulation $riof $ri2,3 $ridiphosphoglycerate $ri(2,3-DPG)?
a. Glycolysis c. Pentose $riphosphate $rishunt
b. Luebering-Rapoport $ r i shunt d. $ r i $ r i Methemoglobin $rireductase
$ r i 21. $ r i $ r i All $riof $rithe $rifollowing $riare $riconsistent $riwith $ria $ri"shift $rito $rithe $riright" $riof $rithe $rihemoglobin-oxygen
dissociation $ricurve
$ri
except:
a. Increased $ri2,3-DPG.
b. 50% $riO2 $ r i saturation $rito $ritissues.
c. Decreased $ri 2,3-DPG.
d. Decreased $rihemoglobin $riaffinity $rifor $riO2.
$ri 22. $ r i $ r i What $riis $rithe $rinormal $riplatelet $ricount $rirange $riper $ricubic $rimillimeter?
a. 100 $rito $ri350 c. 50,000 $rito $ri200,000
b. 150,000 $rito $ri350,000 d. $ r i $ r i 350,000 $rito $ri500,000
$ri 23. $ r i $ r i What $ricryoprotective $riagent $riis $riadded $rito $rired $riblood $ricells $riupon $rifreezing?
a. Dextrose c. Glycerol
b. Adsol d. $ r i $ r i All $riof $rithe $riabove
$ r i 24. $ r i $ r i If $riplatelets $riare $rito $ribe $ristored $rifor $ri5 $ridays $rion $ria $rirotator, $riwhat $riis $rithe $rioptimal $ristorage
$ri temperature?
a. 1°C $rito $ri6°C c. 35°C $rito $ri37°C
b. 20°C $rito $ri24°C d. $ r i $ r i 1°C $rito $ri10°C
$ri 25. $ r i $ r i What $rirole $rido $riplatelets $riplay $riin $rihemostasis?
a. Maintenance $riof $rivascular $riintegrity
b. Initial $riarrest $riof $ribleeding $riby $riplatelet $riplug $riformation
c. Stabilization $riof $rithe $rihemostatic $riplug
d. All $riof $rithe $riabove
$ri 26. $ r i $ r i Which $riof $rithe $rifollowing $ribest $ridescribes $ri"integral" $rimembrane $riproteins?
a. Reside $riat $rithe $ricytoplasmic $risurface $riof $rimembrane
b. Span $rithe $rientire $rimembrane $risurface
c. Form $rithe $rired $riblood $ricell $ricytoskeleton
d. None $riof $rithe $riabove
$ri 27. $ r iHow $riis $ristroma-free $rihemoglobin $risolution $riprepared?
a. Outdated $rired $riblood $ricells $riare $riconcentrated, $riand $ristroma $riis $riremoved.
b. Outdated $rired $riblood $ricells $riare $ridiluted $riwith $risaline, $riand $ristroma $riis $riremoved.
c. Outdated $rired $riblood $ricells $riare $rilysed, $riand $ristroma $riis $riremoved.
d. None $riof $rithe $riabove
$ri 28. $ r i $ r i What $riis $rithe $rinormal $rilife $rispan $riof $rian $riRBC?
a. 100 $ridays c. 120 $rihours
b. 120 $ridays d. $ r i $ r i 2 $ridays
$ri 29. $ r i Regarding $riloss $riof $riRBC $rimembrane $rideformability, $riall $riof $rithe $rifollowing $riare $ritrue $ r i except:
a. Increase $riin$riATP $rilevel.
b. Decrease $riin$riATP $rilevel.
