GEORGETTE MODULE 1 & 2 EXAM
QUESTIONS WITH COMPLETE
SOLUTIONS 2025
,Lithium level - ANSWER0.6-1.2
Lithium toxicity level - ANSWERgreater than or equal to 1.5
what is the gold standard for treating manic episodes? - ANSWERLithium
What drug has evidence of anti-suicidal effects for bipolar disorder? - ANSWERLithium
baseline labs to collect in order to R/O medical diagnoses prior to giving Lithium -
ANSWERTSH (r/o bipolar)
Creatinine (0.6-1.2)
BUN (10-20)
Pregnancy test
ECG if greater than 50 (inverted T-waves)
All psychotropics should have what test prior to giving for child-bearing age? -
ANSWERpregnancy test
what is considered child-bearing age? - ANSWER12-51
SE of Lithium? (endocrine) - ANSWERHYPOthyroidism
SE of Lithium? (CNS) - ANSWER**course hand tremors w/ toxicity
SE of Lithium? (dermatological) - ANSWERMaculopapular rash
SE of Lithium? (GI) - ANSWERdiarrhea, vomiting, cramp, anorexia
**imp. because these become severe w/ toxicity
SE of Lithium? (Renal) - ANSWERdiabetes insipidus (polyuria r/t polydipsia)
SE of Lithium? (Cardiac) - ANSWERT-wave inversions
SE of Lithium? (Hematologic) - ANSWERleukocytosis (increased WBC)
Hypertensive Crisis occurs when..... - ANSWERMAOIs are taken in conjunction w/
foods containing TYRAMINE (dietary precursor of NE)
Hypertensive crisis is _____-__________ and cannot be reversed unless..... -
ANSWERlife-threatening & cannot be reversed unless more MAO is produced by the
body
, Hypertensive crisis & death can occur when MAOIs are taken in conjunction with which
types of meds?? - ANSWER***Meperidine
***Stimulants/other sympathomimetics
Decongestants/TCA/SGA/St. Johns Wort/L-tryptophan
Symptoms of Hypertensive crisis include - ANSWERsudden explosive-like HA in
OCCIPITAL region
Fever**
Treatment of Hypertensive Crisis - ANSWER1. d/c offending agent (MAOI)
2. administer PHENTOLAMINE
3. Stabilize fever
medication to reverse hypertensive crisis w/ MAOI? - ANSWERPhentolamine****
List of common MAOIs (don't need to memorize, just know what it looks like) -
ANSWERIsocarboxazid (Marplan)
Phenelzine (Nardil)
Selegiline (Emsam)
Tranylcypromine (Parnate)
Teratogenic risks of common psych meds (Benzo, Carbamazepine, Lithium, Depakote)
- ANSWERBenzo: floppy baby & cleft palate
Carbamazepine: neural tube defect
Lithium: Epstein's anomaly & Congenital heart defects (esp. 1st trimester)
Depakote: Neural tube defects (spec. spina bifida)
Lamicatal main SE - ANSWERSteven Johnson's Syndrome*** (SE below, KNOW)
- Fever**
- Sore throat (may feel like burning**
- Facial/tongue swelling**
- Skin sloughing***
- Prodromal HA, malaise, Arthralgia, painful mucous membranes may occur BEFORE
rash
Valproic Acid/Divalproex Sodium aka Depakote main SE - ANSWERHepatotoxicity**
Pancreatitis**
Carbamazepine (Tegretol) main SE - ANSWERAgranulocytosis***
Aplastic Anemia***
Steven-Johnson's*** (mainly Asians HLAB-1502 allele)
Aplastic Anemia s/s - ANSWERpallor, fatigue, HA, fever, nose bleeds, bleeding gums,
skin rash, SOB
Carbamazepine when to d/c - ANSWERWBC 2000-3000
QUESTIONS WITH COMPLETE
SOLUTIONS 2025
,Lithium level - ANSWER0.6-1.2
Lithium toxicity level - ANSWERgreater than or equal to 1.5
what is the gold standard for treating manic episodes? - ANSWERLithium
What drug has evidence of anti-suicidal effects for bipolar disorder? - ANSWERLithium
baseline labs to collect in order to R/O medical diagnoses prior to giving Lithium -
ANSWERTSH (r/o bipolar)
Creatinine (0.6-1.2)
BUN (10-20)
Pregnancy test
ECG if greater than 50 (inverted T-waves)
All psychotropics should have what test prior to giving for child-bearing age? -
ANSWERpregnancy test
what is considered child-bearing age? - ANSWER12-51
SE of Lithium? (endocrine) - ANSWERHYPOthyroidism
SE of Lithium? (CNS) - ANSWER**course hand tremors w/ toxicity
SE of Lithium? (dermatological) - ANSWERMaculopapular rash
SE of Lithium? (GI) - ANSWERdiarrhea, vomiting, cramp, anorexia
**imp. because these become severe w/ toxicity
SE of Lithium? (Renal) - ANSWERdiabetes insipidus (polyuria r/t polydipsia)
SE of Lithium? (Cardiac) - ANSWERT-wave inversions
SE of Lithium? (Hematologic) - ANSWERleukocytosis (increased WBC)
Hypertensive Crisis occurs when..... - ANSWERMAOIs are taken in conjunction w/
foods containing TYRAMINE (dietary precursor of NE)
Hypertensive crisis is _____-__________ and cannot be reversed unless..... -
ANSWERlife-threatening & cannot be reversed unless more MAO is produced by the
body
, Hypertensive crisis & death can occur when MAOIs are taken in conjunction with which
types of meds?? - ANSWER***Meperidine
***Stimulants/other sympathomimetics
Decongestants/TCA/SGA/St. Johns Wort/L-tryptophan
Symptoms of Hypertensive crisis include - ANSWERsudden explosive-like HA in
OCCIPITAL region
Fever**
Treatment of Hypertensive Crisis - ANSWER1. d/c offending agent (MAOI)
2. administer PHENTOLAMINE
3. Stabilize fever
medication to reverse hypertensive crisis w/ MAOI? - ANSWERPhentolamine****
List of common MAOIs (don't need to memorize, just know what it looks like) -
ANSWERIsocarboxazid (Marplan)
Phenelzine (Nardil)
Selegiline (Emsam)
Tranylcypromine (Parnate)
Teratogenic risks of common psych meds (Benzo, Carbamazepine, Lithium, Depakote)
- ANSWERBenzo: floppy baby & cleft palate
Carbamazepine: neural tube defect
Lithium: Epstein's anomaly & Congenital heart defects (esp. 1st trimester)
Depakote: Neural tube defects (spec. spina bifida)
Lamicatal main SE - ANSWERSteven Johnson's Syndrome*** (SE below, KNOW)
- Fever**
- Sore throat (may feel like burning**
- Facial/tongue swelling**
- Skin sloughing***
- Prodromal HA, malaise, Arthralgia, painful mucous membranes may occur BEFORE
rash
Valproic Acid/Divalproex Sodium aka Depakote main SE - ANSWERHepatotoxicity**
Pancreatitis**
Carbamazepine (Tegretol) main SE - ANSWERAgranulocytosis***
Aplastic Anemia***
Steven-Johnson's*** (mainly Asians HLAB-1502 allele)
Aplastic Anemia s/s - ANSWERpallor, fatigue, HA, fever, nose bleeds, bleeding gums,
skin rash, SOB
Carbamazepine when to d/c - ANSWERWBC 2000-3000
