NR 546 MIDTERM EXAM ACTUAL EXAM TEST BANK 300 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES

NR 546 MIDTERM EXAM 2023-2025 ACTUAL EXAM
TEST BANK 300 QUESTIONS AND CORRECT
DETAILED ANSWERS WITH RATIONALES |ALREADY
GRADED A+



WHY IS TRAZODONE NOT USED AS A FRONT-LINE
ANTIDEPRESSANT - ANSWER- ITS ANTIDEPRESSANT THAT
HAS A SECONDARY EFFECT OF BLOCKING HISTAMINE AND
ADRENERGIC RECEPTORS
-CAUSES SEDATION AND SOMNOLENCE AND AS A RESULT
*OFTEN USED AS AN ADJUNCT IN THERAPY WHEN A
DEPRESSED PATIENT HAS DIFFICULTY SLEEPING


EFFECT ON NEUROTRANSMITTERS AND SIDE EFFECTS:
SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIS) -
ANSWER- INHIBITS THE REUPTAKE OF SEROTONIN,
WHICH CAN CAUSE NAUSEA, AGITATION, HEADACHE,
AND SEXUAL DYSFUNCTION


EFFECT ON NEUROTRANSMITTERS AND SIDE EFFECTS:
SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITORS
(SNRIS) - ANSWER- INHIBITS THE REUPTAKE OF SEROTONIN
AND NOREPINEPHRINE, WHICH CAN CAUSE NAUSEA,
SWEATING, INSOMNIA, TREMORS, SEXUAL DYSFUNCTION


EFFECT ON NEUROTRANSMITTERS AND SIDE EFFECTS:
TRICYCLIC ANTIDEPRESSANTS - ANSWER- -INHIBITS THE
REUPTAKE OF SEROTONIN AND NOREPINEPHRINE, WHICH
CAN CAUSE SEXUAL DYSFUNCTION
-BLOCKS NOREPINEPHRINE RECEPTORS, WHICH CAN CAUSE
HYPOTENSION AND TACHYCARDIA
-BLOCKS HISTAMINE RECEPTORS, WHICH CAN CAUSE

,SEDATION AND WEIGHT GAIN

,-BLOCKS ACETYLCHOLINE RECEPTORS, WHICH CAN
CAUSE DRY MOUTH, CONSTIPATION, BLURRED VISION,
AND URINARY RETENTION


EFFECT ON NEUROTRANSMITTERS AND SIDE EFFECTS:
MONOAMINE OXIDASE INHIBITORS (MAOIS) - ANSWER-
INCREASES NOREPINEPHRINE AND SEROTONIN BY
INHIBITING THE ENZYME THAT INACTIVATES IT, WHICH CAN
CAUSE SEDATION, DIZZINESS, SEXUAL DYSFUNCTION, AND
HYPERTENSIVE CRISIS


EFFECT ON NEUROTRANSMITTERS AND SIDE EFFECTS:
BENZODIAZEPINES - ANSWER- INCREASES THE RECEPTOR
AFFINITY FOR GABA, WHICH CAN CAUSE DEPENDENCE
AND CONFUSION


EFFECT ON NEUROTRANSMITTERS AND SIDE EFFECTS:
BUPROPION - ANSWER- INHIBITS THE REUPTAKE OF
NOREPINEPHRINE AND DOPAMINE, WHICH CAN CAUSE
INSOMNIA, DRY MOUTH, TREMORS, AND SEIZURES


ANTAGONIST - ANSWER- CAUSES A CONFORMATIONAL
CHANGE THAT STABILIZES THE RECEPTOR IN THE
BASELINE STATE AND THUS IS "SILENT."
-BLOCKS THE ACTION OF A NEUROTRANSMITTER


AGONISTS - ANSWER- FULLY STIMULATE G-PROTEIN-LINKED
RECEPTORS

PARTIAL AGONISTS - ANSWER- STIMULATE RECEPTORS TO
A LESSER DEGREE THAN AN AGONIST OR NATURAL
NEUROTRANSMITTER

, SSRIS, SNRIS, AND TRICYCLIC ANTIDEPRESSANTS INCREASE
LEVELS.
DO NOT IMPACT SEROTONIN LEVELS. -
ANSWER- INCREASE SEROTONIN LEVELS.
BENZODIAZEPINES DO NOT IMPACT SEROTONIN LEVELS.