53. What are the factors that increase the risk for statin myopathy?
Give this one a try later!
, - Advanced age especially > 80 years
- Female gender
- Small body frame, frailty
- Multisystem disease (CKD)
- Postoperative period
- Alcohol abuse
- Concomitant medication use (especially cytochrome interactions)
36. What is the problem when LDL particles are found to be increased and small by
advanced lipid profile measurements?
Give this one a try later!
There is an increased risk of atherogenesis with small particles
Have fibric acid derivatives been shown to reduce morbidity and mortality like
statins?
Give this one a try later!
No.
When possible, use a statin which will also lower triglyceride levels, unless
the triglycerides are greater than 500 mg/dL.
What happens when gemfibrozil and warfarin are used together?
Give this one a try later!
, Gemfibrozil displaces warfarin from albumin increasing the anticoagulant
effect
18. Age, tobacco abuse, diabetes, metabolic syndrome, HTN, obesity, history of MI,
low HDL, sedentary lifestyle, and positive family history of CAD are all risk factors for
____________?
Give this one a try later!
Coronary heart disease
59. A patient complains of myalgias after starting a statin. What are the treatment
options?
Give this one a try later!
- Try stopping the statin to see if the pain improves.
- Try changing to another statin in the same class or try lowering the dose
of the statin. Co-Q 10 has been shown to be helpful in some individuals
with statin induced myopathy Every other day dosing is a possibility
What medication taken thirty (30) minutes before taking nicotinic acid (niacin) will
prevent the synthesis of prostaglandins which mediate the flushing response?
Give this one a try later!
, 325 mg of aspirin
58. What is the treatment of severe myalgias?
Give this one a try later!
If severe muscle symptoms or fatigue of unknown cause develop, hold the
statin and check creatinine and urinalysis to rule-out rhabdomyolysis. Make
sure the patient maintains hydration
55. When should ALT (alanine aminotransferase) be checked in a patient on a statin?
Give this one a try later!
Check at baseline and repeat only if symptoms of hepatotoxicity occur
75. What is the problem with red yeast rice?
Give this one a try later!
It is not regulated and has the same adverse effect profile as statins
1. What are the 4 high risk groups identified in the ACC/AHA Guidelines on the
Treatment of Blood Cholesterol to Reduce ASCVD in Adults that should be treated
with statins?
Give this one a try later!
, - Advanced age especially > 80 years
- Female gender
- Small body frame, frailty
- Multisystem disease (CKD)
- Postoperative period
- Alcohol abuse
- Concomitant medication use (especially cytochrome interactions)
36. What is the problem when LDL particles are found to be increased and small by
advanced lipid profile measurements?
Give this one a try later!
There is an increased risk of atherogenesis with small particles
Have fibric acid derivatives been shown to reduce morbidity and mortality like
statins?
Give this one a try later!
No.
When possible, use a statin which will also lower triglyceride levels, unless
the triglycerides are greater than 500 mg/dL.
What happens when gemfibrozil and warfarin are used together?
Give this one a try later!
, Gemfibrozil displaces warfarin from albumin increasing the anticoagulant
effect
18. Age, tobacco abuse, diabetes, metabolic syndrome, HTN, obesity, history of MI,
low HDL, sedentary lifestyle, and positive family history of CAD are all risk factors for
____________?
Give this one a try later!
Coronary heart disease
59. A patient complains of myalgias after starting a statin. What are the treatment
options?
Give this one a try later!
- Try stopping the statin to see if the pain improves.
- Try changing to another statin in the same class or try lowering the dose
of the statin. Co-Q 10 has been shown to be helpful in some individuals
with statin induced myopathy Every other day dosing is a possibility
What medication taken thirty (30) minutes before taking nicotinic acid (niacin) will
prevent the synthesis of prostaglandins which mediate the flushing response?
Give this one a try later!
, 325 mg of aspirin
58. What is the treatment of severe myalgias?
Give this one a try later!
If severe muscle symptoms or fatigue of unknown cause develop, hold the
statin and check creatinine and urinalysis to rule-out rhabdomyolysis. Make
sure the patient maintains hydration
55. When should ALT (alanine aminotransferase) be checked in a patient on a statin?
Give this one a try later!
Check at baseline and repeat only if symptoms of hepatotoxicity occur
75. What is the problem with red yeast rice?
Give this one a try later!
It is not regulated and has the same adverse effect profile as statins
1. What are the 4 high risk groups identified in the ACC/AHA Guidelines on the
Treatment of Blood Cholesterol to Reduce ASCVD in Adults that should be treated
with statins?
