,Table of Contents
Unit 1: The Cell
Chapter 1: The Cell in Health and Illness
Cell Structure and Function
Chapter 2: Cellular Injury, Adaptations, and Maladaptive Changes
Cellular Adaptations and Maladaptive Changes
• Basic Concepts
Cellular Injury
• Basic Concepts
Cell Degeneration and Death
Clinical Interventions
• Reversing Cell Injury
• Treating Permanent Cell Injury
Chapter 3: Genetic Basis of Disease
Genetics and Disease
• Basic Concepts
• Genetic Assessment
• Gene Therapy: Reversing and Preventing Disease
• Ethical Concerns
Genetic and Chromosomal Disorders
• Pathophysiology of Selected Disorders
Unit 2: Integrated Body Processes
Chapter 4: Stress, Exercise, and Immobility
Stress
• Effects and Treatment
Exercise and Immobility
• Beneficial Effects of Exercise
• Harmful Effects of Physical Inactivity
• Interventions to Counter Immobility
,Chapter 5: Obesity and Nutritional Imbalances
Obesity
• Epidemiology, Etiology, Pathophysiology
• Risk Factors, Clinical Manifestations, Diagnosis, Treatment
Nutritional Imbalances and Eating Disorders
Chapter 6: Pain
Pain Concepts
• Epidemiology
• Basic Physiology and Pathophysiology
Types and Sources of Pain
Pain Management
• Assessment and Treatment
• Selected Clinical Pain Syndromes
Unit 3: Fluid, Electrolyte, and Acid–Base Homeostasis
Chapter 7: Fluid and Electrolyte Imbalances
Fluid and Electrolyte Balance
• Basic Concepts
• Pathophysiology
• Assessment
Electrolyte Imbalances
Chapter 8: Acid–Base Imbalances
Acid–Base Balance
• Basic and Pathophysiological Concepts
Unit 4: Infection and Inflammation
Chapter 9: Inflammation and Dysfunctional Wound Healing
Inflammatory Response
, • Mechanisms and Treatments
Tissue Repair and Wound Healing
Chapter 10: Infectious Diseases
Infection
• Basic Concepts
• Bacterial, Viral, Fungal, and Parasitic Infections
Chapter 11: Immune System Disorders
Immunity and Hypersensitivity
• Basic Concepts and Vaccines
Autoimmune and Immunodeficiency Disorders
• Pathophysiology
HIV Infection
Unit 5: Hematological Disorders
Chapter 12: White Blood Cell Disorders
White Blood Cells
• Function and Pathophysiology
• Selected Disorders
Chapter 13: Red Blood Cell Disorders
Red Blood Cells
• Physiology, Pathophysiology
• Selected Disorders
Chapter 14: Platelet, Hemostasis, and Coagulation Disorders
Bleeding and Clotting
• Basic Physiology and Pathophysiology
• Assessment and Treatment
• Selected Coagulation Disorders
,Unit 6: Cardiovascular Disorders
Chapter 15: Arterial Disorders
Arterial System
• Structure, Function, Pathophysiology
Chapter 16: Ischemic Heart Disease and Conduction Disorders
Heart Structure and Function
• Conduction System
• Selected Disorders
Chapter 17: Heart Failure
Heart Function and Failure
• Basic Physiology and Pathophysiology
Chapter 18: Valvular Heart Disease
Cardiac Valve Dysfunction
• Epidemiology, Function, Assessment, and Selected Disorders
Chapter 19: Venous System Disorders
Venous Dysfunction
• Structure, Function, Pathophysiology
• Selected Disorders
Unit 7: Pulmonary Disorders
Chapter 20: Respiratory Inflammation and Infection
Respiratory Function
• Physiology, Gas Exchange, Pathophysiology
• Assessment
• Upper and Lower Respiratory Tract Disorders
,Chapter 21: Restrictive and Obstructive Pulmonary Disorders
Pulmonary Disorders
• Structure, Function, Pathophysiology
• Assessment and Treatment
• Obstructive, Restrictive, and Vascular Disorders
Unit 8: Renal and Urological Disorders
Chapter 22: Renal Disorders
Renal Function and Disorders
• Epidemiology, Physiology, Pathophysiology
• Assessment, Treatment, and Selected Disorders
Chapter 23: Urological Disorders
Urological Function and Disorders
• Epidemiology, Physiology, Pathophysiology
• Assessment, Treatment, and Selected Disorders
Unit 9: Hormonal and Reproductive Disorders
Chapter 24: Endocrine Disorders
Endocrine System
• Epidemiology, Function, Pathophysiology
• Assessment, Treatment, and Selected Disorders
Chapter 25: Diabetes Mellitus and Metabolic Syndrome
Diabetes
• Epidemiology, Etiology, Metabolism
• Type 1 and Type 2: Mechanism, Manifestations
• Gestational Diabetes
• Diagnosis, Complications, Treatment
,Chapter 26: Female Reproductive System Disorders
Female Reproductive Health
• Epidemiology, Physiology, Pathophysiology
• Assessment, Treatment, Selected Disorders
Chapter 27: Male Reproductive System Disorders
Male Reproductive Health
• Epidemiology, Function, Dysfunction
• Assessment, Treatment, Selected Disorders
Chapter 28: Sexually Transmitted Infections
STIs and Sexual Health
• Epidemiology, Pathophysiology
• LGBTQ+ Health Needs
Unit 10: Gastrointestinal Disorders
Chapter 29: Esophagus, Stomach, and Small Intestine Disorders
Upper GI Function and Disorders
• Epidemiology, Physiology, Pathophysiology
• Selected Disorders
Chapter 30: Large Intestine Disorders
Large Intestine Function
• Pathophysiology, Assessment, Treatment
• Selected Disorders
Chapter 31: Liver Infection, Inflammation, and Cirrhosis
Liver Function and Dysfunction
• Epidemiology, Pathophysiology
• Assessment, Treatment, Selected Disorders
,Chapter 32: Gallbladder, Pancreas, and Biliary Disorders
Biliary System Function and Disorders
• Epidemiology, Pathophysiology
• Assessment, Treatment, Selected Disorders
Unit 11: Neurological Disorders
Chapter 33: Cerebrovascular Disorders
Cerebrovascular System
• Structure, Function, Pathophysiology
• Assessment
Chapter 34: Chronic and Degenerative Neurological Disorders
Neurological Function and Dysfunction
• Neuroanatomy, Pathophysiology
• Assessment
• Chronic and Degenerative Disorders
Chapter 35: Brain and Spinal Cord Injury
Neurotrauma
• Epidemiology, Pathophysiology, Assessment
• TBI and Spinal Cord Injury
Chapter 36: Psychobiology of Behavioral Disorders
Psychobiology and Behavior
• Physiology, Neurotransmitters
• Psychiatric Assessment and Treatment
• Selected Disorders
Unit 12: Musculoskeletal Disorders
Chapter 37: Musculoskeletal Trauma
,Trauma and Bone Injury
• Epidemiology, Pathophysiology, Assessment
• Treatment, Complications, Selected Disorders
Chapter 38: Degenerative Musculoskeletal Disorders
Degenerative Conditions
• Physiology, Pathophysiology
• Assessment, Diagnosis, Treatment
• Selected Disorders
Chapter 39: Infectious and Inflammatory Musculoskeletal Disorders
Infection and Inflammation in Muscles
• Pathophysiology, Assessment, Diagnosis
• Treatment, Selected Disorders
Unit 13: Cancer
Chapter 40: Cancer
Oncology
• Epidemiology, Concepts, Assessment, Diagnosis, Treatment
• Selected Types of Cancer
Unit 14: Integumentary Disorders
Chapter 41: Skin Disorders
Skin Health
• Structure, Assessment, Pathophysiology
• Treatment
• Precancerous, Cancerous, Infectious, Autoimmune, and Inflammatory Skin Conditions
Chapter 42: Burns
Burn Injury
, • Epidemiology, Etiology, Pathophysiology
• Diagnosis, Lab Parameters, Treatment, Pain Management
• Common Complications
Unit 15: Sensory Disorders
Chapter 43: Eye Disorders
Visual System
• Structure, Function, Pathophysiology
• Assessment, Treatment
• Selected Disorders
Chapter 44: Ear Disorders
Auditory System
• Anatomy, Function, Pathophysiology
• Assessment, Diagnosis, Treatment
• Selected Disorders
Unit 16: Aging and Multisystem Disorders
Chapter 45: Physiological Changes of Aging
Aging Process
• Life Span, Functional Changes
• Age-Related Disorders
Chapter 46: SIRS, Sepsis, Shock, MODS, and Death
Critical Conditions
• Epidemiology, Etiology, Pathophysiology
• Systemic Illnesses, Assessment, Treatment
• Organ Dysfunction, Death Concepts
.
Unit 1: The Cell
Chapter 1: The Cell in Health and Illness
Cell Structure and Function
Chapter 2: Cellular Injury, Adaptations, and Maladaptive Changes
Cellular Adaptations and Maladaptive Changes
• Basic Concepts
Cellular Injury
• Basic Concepts
Cell Degeneration and Death
Clinical Interventions
• Reversing Cell Injury
• Treating Permanent Cell Injury
Chapter 3: Genetic Basis of Disease
Genetics and Disease
• Basic Concepts
• Genetic Assessment
• Gene Therapy: Reversing and Preventing Disease
• Ethical Concerns
Genetic and Chromosomal Disorders
• Pathophysiology of Selected Disorders
Unit 2: Integrated Body Processes
Chapter 4: Stress, Exercise, and Immobility
Stress
• Effects and Treatment
Exercise and Immobility
• Beneficial Effects of Exercise
• Harmful Effects of Physical Inactivity
• Interventions to Counter Immobility
,Chapter 5: Obesity and Nutritional Imbalances
Obesity
• Epidemiology, Etiology, Pathophysiology
• Risk Factors, Clinical Manifestations, Diagnosis, Treatment
Nutritional Imbalances and Eating Disorders
Chapter 6: Pain
Pain Concepts
• Epidemiology
• Basic Physiology and Pathophysiology
Types and Sources of Pain
Pain Management
• Assessment and Treatment
• Selected Clinical Pain Syndromes
Unit 3: Fluid, Electrolyte, and Acid–Base Homeostasis
Chapter 7: Fluid and Electrolyte Imbalances
Fluid and Electrolyte Balance
• Basic Concepts
• Pathophysiology
• Assessment
Electrolyte Imbalances
Chapter 8: Acid–Base Imbalances
Acid–Base Balance
• Basic and Pathophysiological Concepts
Unit 4: Infection and Inflammation
Chapter 9: Inflammation and Dysfunctional Wound Healing
Inflammatory Response
, • Mechanisms and Treatments
Tissue Repair and Wound Healing
Chapter 10: Infectious Diseases
Infection
• Basic Concepts
• Bacterial, Viral, Fungal, and Parasitic Infections
Chapter 11: Immune System Disorders
Immunity and Hypersensitivity
• Basic Concepts and Vaccines
Autoimmune and Immunodeficiency Disorders
• Pathophysiology
HIV Infection
Unit 5: Hematological Disorders
Chapter 12: White Blood Cell Disorders
White Blood Cells
• Function and Pathophysiology
• Selected Disorders
Chapter 13: Red Blood Cell Disorders
Red Blood Cells
• Physiology, Pathophysiology
• Selected Disorders
Chapter 14: Platelet, Hemostasis, and Coagulation Disorders
Bleeding and Clotting
• Basic Physiology and Pathophysiology
• Assessment and Treatment
• Selected Coagulation Disorders
,Unit 6: Cardiovascular Disorders
Chapter 15: Arterial Disorders
Arterial System
• Structure, Function, Pathophysiology
Chapter 16: Ischemic Heart Disease and Conduction Disorders
Heart Structure and Function
• Conduction System
• Selected Disorders
Chapter 17: Heart Failure
Heart Function and Failure
• Basic Physiology and Pathophysiology
Chapter 18: Valvular Heart Disease
Cardiac Valve Dysfunction
• Epidemiology, Function, Assessment, and Selected Disorders
Chapter 19: Venous System Disorders
Venous Dysfunction
• Structure, Function, Pathophysiology
• Selected Disorders
Unit 7: Pulmonary Disorders
Chapter 20: Respiratory Inflammation and Infection
Respiratory Function
• Physiology, Gas Exchange, Pathophysiology
• Assessment
• Upper and Lower Respiratory Tract Disorders
,Chapter 21: Restrictive and Obstructive Pulmonary Disorders
Pulmonary Disorders
• Structure, Function, Pathophysiology
• Assessment and Treatment
• Obstructive, Restrictive, and Vascular Disorders
Unit 8: Renal and Urological Disorders
Chapter 22: Renal Disorders
Renal Function and Disorders
• Epidemiology, Physiology, Pathophysiology
• Assessment, Treatment, and Selected Disorders
Chapter 23: Urological Disorders
Urological Function and Disorders
• Epidemiology, Physiology, Pathophysiology
• Assessment, Treatment, and Selected Disorders
Unit 9: Hormonal and Reproductive Disorders
Chapter 24: Endocrine Disorders
Endocrine System
• Epidemiology, Function, Pathophysiology
• Assessment, Treatment, and Selected Disorders
Chapter 25: Diabetes Mellitus and Metabolic Syndrome
Diabetes
• Epidemiology, Etiology, Metabolism
• Type 1 and Type 2: Mechanism, Manifestations
• Gestational Diabetes
• Diagnosis, Complications, Treatment
,Chapter 26: Female Reproductive System Disorders
Female Reproductive Health
• Epidemiology, Physiology, Pathophysiology
• Assessment, Treatment, Selected Disorders
Chapter 27: Male Reproductive System Disorders
Male Reproductive Health
• Epidemiology, Function, Dysfunction
• Assessment, Treatment, Selected Disorders
Chapter 28: Sexually Transmitted Infections
STIs and Sexual Health
• Epidemiology, Pathophysiology
• LGBTQ+ Health Needs
Unit 10: Gastrointestinal Disorders
Chapter 29: Esophagus, Stomach, and Small Intestine Disorders
Upper GI Function and Disorders
• Epidemiology, Physiology, Pathophysiology
• Selected Disorders
Chapter 30: Large Intestine Disorders
Large Intestine Function
• Pathophysiology, Assessment, Treatment
• Selected Disorders
Chapter 31: Liver Infection, Inflammation, and Cirrhosis
Liver Function and Dysfunction
• Epidemiology, Pathophysiology
• Assessment, Treatment, Selected Disorders
,Chapter 32: Gallbladder, Pancreas, and Biliary Disorders
Biliary System Function and Disorders
• Epidemiology, Pathophysiology
• Assessment, Treatment, Selected Disorders
Unit 11: Neurological Disorders
Chapter 33: Cerebrovascular Disorders
Cerebrovascular System
• Structure, Function, Pathophysiology
• Assessment
Chapter 34: Chronic and Degenerative Neurological Disorders
Neurological Function and Dysfunction
• Neuroanatomy, Pathophysiology
• Assessment
• Chronic and Degenerative Disorders
Chapter 35: Brain and Spinal Cord Injury
Neurotrauma
• Epidemiology, Pathophysiology, Assessment
• TBI and Spinal Cord Injury
Chapter 36: Psychobiology of Behavioral Disorders
Psychobiology and Behavior
• Physiology, Neurotransmitters
• Psychiatric Assessment and Treatment
• Selected Disorders
Unit 12: Musculoskeletal Disorders
Chapter 37: Musculoskeletal Trauma
,Trauma and Bone Injury
• Epidemiology, Pathophysiology, Assessment
• Treatment, Complications, Selected Disorders
Chapter 38: Degenerative Musculoskeletal Disorders
Degenerative Conditions
• Physiology, Pathophysiology
• Assessment, Diagnosis, Treatment
• Selected Disorders
Chapter 39: Infectious and Inflammatory Musculoskeletal Disorders
Infection and Inflammation in Muscles
• Pathophysiology, Assessment, Diagnosis
• Treatment, Selected Disorders
Unit 13: Cancer
Chapter 40: Cancer
Oncology
• Epidemiology, Concepts, Assessment, Diagnosis, Treatment
• Selected Types of Cancer
Unit 14: Integumentary Disorders
Chapter 41: Skin Disorders
Skin Health
• Structure, Assessment, Pathophysiology
• Treatment
• Precancerous, Cancerous, Infectious, Autoimmune, and Inflammatory Skin Conditions
Chapter 42: Burns
Burn Injury
, • Epidemiology, Etiology, Pathophysiology
• Diagnosis, Lab Parameters, Treatment, Pain Management
• Common Complications
Unit 15: Sensory Disorders
Chapter 43: Eye Disorders
Visual System
• Structure, Function, Pathophysiology
• Assessment, Treatment
• Selected Disorders
Chapter 44: Ear Disorders
Auditory System
• Anatomy, Function, Pathophysiology
• Assessment, Diagnosis, Treatment
• Selected Disorders
Unit 16: Aging and Multisystem Disorders
Chapter 45: Physiological Changes of Aging
Aging Process
• Life Span, Functional Changes
• Age-Related Disorders
Chapter 46: SIRS, Sepsis, Shock, MODS, and Death
Critical Conditions
• Epidemiology, Etiology, Pathophysiology
• Systemic Illnesses, Assessment, Treatment
• Organ Dysfunction, Death Concepts
.
