ASCP MLT Immunology UPDATED
ACTUAL Exam Questions and CORRECT
Answers
The serum hemolytic complement level (CH50):
A.is a measure of total complement activity
B.provides the same information as a serum factor B level
C.is detectable when any component of the classical system is congenitally absent
D.can be calculated from the serum concentrations of the individual components - CORRECT
ANSWER - A.is a measure of total complement activity
Normal serum constituents that can rapidly increase during infection, injury or trauma are
referred to as:
A.haptens
B.acute phase reactants
C.opsonins
D.chemotaxins - CORRECT ANSWER - B.acute phase reactants
Chronic carriers of HBV:
A.have chronic symptoms of hepatitis
B.continue to carry HBV
C.do not transmit infection
D.carry HBV but are not infectious - CORRECT ANSWER - B.continue to carry HBV
Which of the following cytokines is produced by an activated CD8 cytotoxic T cell?
A.interleukin 13 (IL-13)
B.interleukin 5 (IL-5)
C.stromal cell-derived factor 1 (SDF-1)
,D.interferon gamma (IFNγ) - CORRECT ANSWER - D.interferon gamma (IFNγ)
The IgM molecule is a:
A.dimer
B.trimer
C.tetramer
D.pentamer - CORRECT ANSWER - D.pentamer
Treatment of IgG with papain results in how many fragments from each immunoglobulin
molecule?
A.2
B.3
C.4
D.5 - CORRECT ANSWER - B.3
The process of centering the sample core within the sheath fluid is known as:
A.acoustic focusing
B.hydrodynamic focusing
C.liquid focusing
D.isoelectric focusing - CORRECT ANSWER - B.hydrodynamic focusing
Which immunologic mechanism is usually involved in bronchial asthma?
A.immediate hypersensitivity
B.antibody mediated cytotoxicity
C.immune complex
D.delayed hypersensitivity - CORRECT ANSWER - A.immediate hypersensitivity
The 20 nm spheres and filamentous structures of HBV are:
,A.infectious
B.circulating aggregates of HBcAg
C.circulating aggregates of HBsAg
D.highly infectious when present in great abundance - CORRECT ANSWER -
C.circulating aggregates of HBsAg
Which of the following thyroid antibodies causes hyperthyroidism by binding to the TSH
receptor?
A.anti-thyroglobulin (Tg)
B.anti-thyroperoxidase (TPO)
C.anti-thyroid-stimulating hormone receptor (TRAb)
D.anti-thyroid-stimulating hormone (TSH) - CORRECT ANSWER - C.anti-thyroid-
stimulating hormone receptor (TRAb)
Immunoglobulin idiotypic diversity is best explained by the theory of:
A.somatic mutation
B.germ line recombination
C.antigen induction
D.clonal selection - CORRECT ANSWER - B.germ line recombination
Which of the following mediators is released during T-cell activation?
A.immunoglobulins
B.complement C3
C.histamine
D.cytokines - CORRECT ANSWER - D.cytokines
T lymphocytes that possess the CD8 surface marker mediate which of the following T-cell
functions?
A.delayed-type hypersensitivity
, B.regulatory
C.cytotoxic
D.helper - CORRECT ANSWER - C.cytotoxic
The visible serological reaction between soluble antigen and its specific antibody is:
A.sensitization
B.precipitation
C.agglutination
D.opsonization - CORRECT ANSWER - B.precipitation
In immunofixation electrophoresis:
A.the antibody reacts with the antigen and then the complex is electrophoresed
B.the antigen is electrophoresed into an antibody containing gel
C.the antigen is electrophoresed and then monospecific antisera is reacted with it
D.the antigen is electrophoresed, transferred to nitrocellulose and then antibody reacts with it and
an EIA is performed - CORRECT ANSWER - C.the antigen is electrophoresed and then
monospecific antisera is reacted with it
A normal control for a B lymphocyte enumeration assay should have a value of what percentage
of total lymphocytes counted?
A.21%
B.48%
C.76%
D.89% - CORRECT ANSWER - A.21%
Which of the these substances will not stimulate an immune response unless it is bound to a
larger molecule?
A.antigen
B.adjuvant
ACTUAL Exam Questions and CORRECT
Answers
The serum hemolytic complement level (CH50):
A.is a measure of total complement activity
B.provides the same information as a serum factor B level
C.is detectable when any component of the classical system is congenitally absent
D.can be calculated from the serum concentrations of the individual components - CORRECT
ANSWER - A.is a measure of total complement activity
Normal serum constituents that can rapidly increase during infection, injury or trauma are
referred to as:
A.haptens
B.acute phase reactants
C.opsonins
D.chemotaxins - CORRECT ANSWER - B.acute phase reactants
Chronic carriers of HBV:
A.have chronic symptoms of hepatitis
B.continue to carry HBV
C.do not transmit infection
D.carry HBV but are not infectious - CORRECT ANSWER - B.continue to carry HBV
Which of the following cytokines is produced by an activated CD8 cytotoxic T cell?
A.interleukin 13 (IL-13)
B.interleukin 5 (IL-5)
C.stromal cell-derived factor 1 (SDF-1)
,D.interferon gamma (IFNγ) - CORRECT ANSWER - D.interferon gamma (IFNγ)
The IgM molecule is a:
A.dimer
B.trimer
C.tetramer
D.pentamer - CORRECT ANSWER - D.pentamer
Treatment of IgG with papain results in how many fragments from each immunoglobulin
molecule?
A.2
B.3
C.4
D.5 - CORRECT ANSWER - B.3
The process of centering the sample core within the sheath fluid is known as:
A.acoustic focusing
B.hydrodynamic focusing
C.liquid focusing
D.isoelectric focusing - CORRECT ANSWER - B.hydrodynamic focusing
Which immunologic mechanism is usually involved in bronchial asthma?
A.immediate hypersensitivity
B.antibody mediated cytotoxicity
C.immune complex
D.delayed hypersensitivity - CORRECT ANSWER - A.immediate hypersensitivity
The 20 nm spheres and filamentous structures of HBV are:
,A.infectious
B.circulating aggregates of HBcAg
C.circulating aggregates of HBsAg
D.highly infectious when present in great abundance - CORRECT ANSWER -
C.circulating aggregates of HBsAg
Which of the following thyroid antibodies causes hyperthyroidism by binding to the TSH
receptor?
A.anti-thyroglobulin (Tg)
B.anti-thyroperoxidase (TPO)
C.anti-thyroid-stimulating hormone receptor (TRAb)
D.anti-thyroid-stimulating hormone (TSH) - CORRECT ANSWER - C.anti-thyroid-
stimulating hormone receptor (TRAb)
Immunoglobulin idiotypic diversity is best explained by the theory of:
A.somatic mutation
B.germ line recombination
C.antigen induction
D.clonal selection - CORRECT ANSWER - B.germ line recombination
Which of the following mediators is released during T-cell activation?
A.immunoglobulins
B.complement C3
C.histamine
D.cytokines - CORRECT ANSWER - D.cytokines
T lymphocytes that possess the CD8 surface marker mediate which of the following T-cell
functions?
A.delayed-type hypersensitivity
, B.regulatory
C.cytotoxic
D.helper - CORRECT ANSWER - C.cytotoxic
The visible serological reaction between soluble antigen and its specific antibody is:
A.sensitization
B.precipitation
C.agglutination
D.opsonization - CORRECT ANSWER - B.precipitation
In immunofixation electrophoresis:
A.the antibody reacts with the antigen and then the complex is electrophoresed
B.the antigen is electrophoresed into an antibody containing gel
C.the antigen is electrophoresed and then monospecific antisera is reacted with it
D.the antigen is electrophoresed, transferred to nitrocellulose and then antibody reacts with it and
an EIA is performed - CORRECT ANSWER - C.the antigen is electrophoresed and then
monospecific antisera is reacted with it
A normal control for a B lymphocyte enumeration assay should have a value of what percentage
of total lymphocytes counted?
A.21%
B.48%
C.76%
D.89% - CORRECT ANSWER - A.21%
Which of the these substances will not stimulate an immune response unless it is bound to a
larger molecule?
A.antigen
B.adjuvant
