IUPUI Biophysical Processes Exam 3: Complete Q&A with Verified Solutions-2025/2026

Define GERD: - Mucosal damage caused by reflux (backflow) of stomach acid into the esophagus, causing irritation/esophagitis Define GER: - The transfer of gastric contents into the esophagus. - Peak incidence is in infants 4 months of age and generally resolves spontaneously around 12 months of age. - GER Becomes GERD when complications develop. True or False: GER may resolve itself - True! In some children, may resolve spontaneously as their esophageal sphincter grows stronger, over the first year of life. What are some predisposing factors to GERD/GER? - - Incompetent lower esophageal sphincter (certain medications & foods exacerbate this) - Decreased esophageal clearance - Decreased gastric emptying - Increased intraabdominal pressure (obesity, hiatal hernia)