WGUC785
Biochemistry
UnitExam
Q&A
LatestVersion
2025/26
,WGU C785 Biochemistry Unit Exam
Questions and Answers 2025/2026
WhichKlevelKofKproteinKstructureKisKdisruptedKthroughKtheKhydrolysisKofKpeptideKbonds?
Quaternary
Tertiary
Primary
SecondaryKAns
wer-KPrimary
TheKprimaryKstructureKofKaKproteinKisKtheKsequenceKofKaminoKacidsKheldKtogetherKbyKpept
ideKbonds.KPeptideKbondsKareKformedKbyKdehydrationKreactionsKandKdisruptedKbyKhydroly
sis.
AKmutationKinKtheKbeta-
hemoglobinKgene,KwhichKresultsKinKtheKreplacementKofKtheKaminoKacidKglutamateKinKposit
ionK6KwithKtheKaminoKacidKvaline,KleadsKtoKtheKdevelopmentKofKsickleKcellKanemia.KTheKst
ructuresKofKglutamateKandKvalineKareKshownKbelow.
IfKtheKbetaKhemoglobinKgeneKinKaKpatientKwithKsickle-
cellKanemiaKwereKtoKbeKeditedKsoKthatKtheKvalineKinKpositionK6KwasKreplacedKwithKaKdiffere
ntKaminoKacid,KwhichKreplacementKforKvalineKwouldKbeKexpectedKtoKhaveKtheKbestKclinicalK
outcome,KinKtheory,KforKtheKpatient?K(AssumeKtheKvalineKcanKpotentiallyKbeKreplacedKwithK
anyKaminoKacidKotherKthanKglutamate.)
Answer-
KTheKoriginalKaminoKacidKinKaKhealthyKpatientKisKglutamate,KwhichKisKnegativelyKcharged.K
TheKmutatedKaminoKacidKisKvaline,KwhichKisKnon-
polar.KValineKisKcausingKsickleKcellKanemia.KTheKbestKaminoKacidKtoKreplaceKvalineKsoKtha
tKtheKpatientKisKhealthyKagainKwouldKbeKtheKoneKmostKlikeKglutamate,KsoKanyKnegativelyKc
hargedKaminoKacid.
Secondary,Ktertiary,KandKquaternaryKlevelsKofKproteinKstructureKcanKallKbeKimpactedKbyKexpo
singKaKproteinKtoKwhichKtreatment?
ChangeKofKaKhydrophobicKaminoKacidKtoKaKdifferentKhydrophobicKaminoKacid
AdditionKofKaKreducingKagent
PlacementKofKtheKproteinKinKaKsolutionKwithKaKlowKpH
IncreaseKinKtheKconcentrationKofKtheKproteinKinKsolution
, Answer-KPlacementKofKtheKproteinKinKaKsolutionKwithKaKlowKpH
ChangesKinKpHKaffectKhydrogenKbondsKandKionicKbonds.KHydrogenKbondsKinKtheKbackbo
neKofKaminoKacidsKoccurKinKsecondaryKstructure,KandKbothKhydrogenKbondsKandKionicKbo
ndsKoccurKinKtheKsideKchainsKofKaminoKacidsKinKtertiaryKstructure.
AnKincreaseKinKbeta-
pleatedKsheetKstructureKinKsomeKbrainKproteinsKcanKleadKtoKanKincreaseKinKamyloidKdepo
sitKformation,KcharacteristicKofKsomeKneurodegenerativeKdiseases.KWhatKisKtheKprimaryKb
iochemicalKprocessKthatKfollowsKtheKincreaseKinKbeta-
KpleatedKsheetKstructureKthatKleadsKtoKtheKdevelopmentKofKtheKamyloidKdeposits?
AnKincreaseKinKglycogenKformationKinKtheKbrainKcells
AggregationKofKtheKproteinsKinKtheKbrain
SecretionKofKglucagon,KleadingKtoKexcessiveKketogenesis
AnKincreaseKinKanaerobicKmetabolismKofKglucoseKinKtheKbrain
KAnswer-KAggregationKofKtheKproteinsKinKtheKbrain
ThisKquestionKisKdescribingKchangesKinKproteinKstructure.KAggregationKoccursKwhenKprot
einsKclumpKtogetherKinappropriately,KcausingKplaquesKlikeKamyloidKdepositsKtoKaccumula
te.
WhichKlevelKofKproteinKstructureKisKdeterminedKbyKtheKsequenceKofKaminoKacids?
SecondaryKstructure
QuaternaryKstructure
TertiaryKstructure
PrimaryKstructure
Answer-KPrimaryKstructure
TheKprimaryKstructureKofKaKproteinKisKsimplyKtheKsequenceKofKaminoKacidsKheldKtogetherK
byKpeptideKbonds.
WhichKforceKisKmostKinfluentialKinKdeterminingKtheKsecondaryKstructureKofKaKprotein?
HydrophobicKeffect
DisulfideKbonding
HydrogenKbonding
Biochemistry
UnitExam
Q&A
LatestVersion
2025/26
,WGU C785 Biochemistry Unit Exam
Questions and Answers 2025/2026
WhichKlevelKofKproteinKstructureKisKdisruptedKthroughKtheKhydrolysisKofKpeptideKbonds?
Quaternary
Tertiary
Primary
SecondaryKAns
wer-KPrimary
TheKprimaryKstructureKofKaKproteinKisKtheKsequenceKofKaminoKacidsKheldKtogetherKbyKpept
ideKbonds.KPeptideKbondsKareKformedKbyKdehydrationKreactionsKandKdisruptedKbyKhydroly
sis.
AKmutationKinKtheKbeta-
hemoglobinKgene,KwhichKresultsKinKtheKreplacementKofKtheKaminoKacidKglutamateKinKposit
ionK6KwithKtheKaminoKacidKvaline,KleadsKtoKtheKdevelopmentKofKsickleKcellKanemia.KTheKst
ructuresKofKglutamateKandKvalineKareKshownKbelow.
IfKtheKbetaKhemoglobinKgeneKinKaKpatientKwithKsickle-
cellKanemiaKwereKtoKbeKeditedKsoKthatKtheKvalineKinKpositionK6KwasKreplacedKwithKaKdiffere
ntKaminoKacid,KwhichKreplacementKforKvalineKwouldKbeKexpectedKtoKhaveKtheKbestKclinicalK
outcome,KinKtheory,KforKtheKpatient?K(AssumeKtheKvalineKcanKpotentiallyKbeKreplacedKwithK
anyKaminoKacidKotherKthanKglutamate.)
Answer-
KTheKoriginalKaminoKacidKinKaKhealthyKpatientKisKglutamate,KwhichKisKnegativelyKcharged.K
TheKmutatedKaminoKacidKisKvaline,KwhichKisKnon-
polar.KValineKisKcausingKsickleKcellKanemia.KTheKbestKaminoKacidKtoKreplaceKvalineKsoKtha
tKtheKpatientKisKhealthyKagainKwouldKbeKtheKoneKmostKlikeKglutamate,KsoKanyKnegativelyKc
hargedKaminoKacid.
Secondary,Ktertiary,KandKquaternaryKlevelsKofKproteinKstructureKcanKallKbeKimpactedKbyKexpo
singKaKproteinKtoKwhichKtreatment?
ChangeKofKaKhydrophobicKaminoKacidKtoKaKdifferentKhydrophobicKaminoKacid
AdditionKofKaKreducingKagent
PlacementKofKtheKproteinKinKaKsolutionKwithKaKlowKpH
IncreaseKinKtheKconcentrationKofKtheKproteinKinKsolution
, Answer-KPlacementKofKtheKproteinKinKaKsolutionKwithKaKlowKpH
ChangesKinKpHKaffectKhydrogenKbondsKandKionicKbonds.KHydrogenKbondsKinKtheKbackbo
neKofKaminoKacidsKoccurKinKsecondaryKstructure,KandKbothKhydrogenKbondsKandKionicKbo
ndsKoccurKinKtheKsideKchainsKofKaminoKacidsKinKtertiaryKstructure.
AnKincreaseKinKbeta-
pleatedKsheetKstructureKinKsomeKbrainKproteinsKcanKleadKtoKanKincreaseKinKamyloidKdepo
sitKformation,KcharacteristicKofKsomeKneurodegenerativeKdiseases.KWhatKisKtheKprimaryKb
iochemicalKprocessKthatKfollowsKtheKincreaseKinKbeta-
KpleatedKsheetKstructureKthatKleadsKtoKtheKdevelopmentKofKtheKamyloidKdeposits?
AnKincreaseKinKglycogenKformationKinKtheKbrainKcells
AggregationKofKtheKproteinsKinKtheKbrain
SecretionKofKglucagon,KleadingKtoKexcessiveKketogenesis
AnKincreaseKinKanaerobicKmetabolismKofKglucoseKinKtheKbrain
KAnswer-KAggregationKofKtheKproteinsKinKtheKbrain
ThisKquestionKisKdescribingKchangesKinKproteinKstructure.KAggregationKoccursKwhenKprot
einsKclumpKtogetherKinappropriately,KcausingKplaquesKlikeKamyloidKdepositsKtoKaccumula
te.
WhichKlevelKofKproteinKstructureKisKdeterminedKbyKtheKsequenceKofKaminoKacids?
SecondaryKstructure
QuaternaryKstructure
TertiaryKstructure
PrimaryKstructure
Answer-KPrimaryKstructure
TheKprimaryKstructureKofKaKproteinKisKsimplyKtheKsequenceKofKaminoKacidsKheldKtogetherK
byKpeptideKbonds.
WhichKforceKisKmostKinfluentialKinKdeterminingKtheKsecondaryKstructureKofKaKprotein?
HydrophobicKeffect
DisulfideKbonding
HydrogenKbonding